Articles tagged "Pediatric"

2020 American Transplant Congress
Impact of Immunosuppression Protocol on the Incidence of EBV Viremia and PTLD in Pediatric Kidney Transplant Recipients: A Single Center Experience
K. Bowers¹, V. M. Panzarino¹, A. Campos¹, J. Buggs², V. D. Bowers²
¹Pediatrics, USF, Tampa, FL, ²Transplant Surgery, TGH, Tampa, FL
*Purpose: The purpose of this study was to evaluate the efficacy of an immunosuppression protocol change, which included avoidance of anti-thymocyte globulin for induction and…
2020 American Transplant Congress
Brincidofovir for Treatment of Disseminated Human Adenovirus Infection in Pediatric Solid Organ Transplant Recipients
J. Londeree¹, R. Garro¹, R. Romero², R. George¹, P. Winterberg¹, R. Liverman³, A. Serluco³, S. Shin¹, I. Yildirim⁴
¹Pediatric Nephrology, Emory, Atlanta, GA, ²Pediatric Hepatology and Gastroenterology, Emory, Atlanta, GA, ³Pharmacy, Children's Healthcare of Atlanta, Atlanta, GA, ⁴Pediatric Infectious Disease, Emory, Atlanta, GA
*Purpose: Brincidofovir (BCV) is an investigational antiviral drug with potency against Human Adenovirus (HAdV). We describe four cases of disseminated HAdV infection treated with (BCV)…
2020 American Transplant Congress
High Intra-Patient Variability of Tacrolimus in Pediatric and Adolescent Renal Transplant Recipients is Associated with Worse Graft Outcomes
K. Piburn¹, L. Maestretti², R. Shetty², M. V. Patton², A. McGrath², W. Concepcion¹, A. Chaudhuri¹, P. C. Grimm¹, V. K. Sigurjonsdottir³
¹Stanford University, Palo Alto, CA, ²Lucile Packard Children's Hospital Stanford, Palo Alto, CA, ³Landspitali - The National University Hospital of Iceland, Reykjavik, Iceland
*Purpose: High intra-patient variability (IPV) in tacrolimus (TAC) levels is associated with de novo donor-specific antibodies (dnDSA) and graft loss. We examined the natural history…
2020 American Transplant Congress
Domino Transplantation – Expanding the Liver Donor Pool to the Pediatric Recipient
U. Ekong¹, N. Yazigi¹, K. Khan¹, S. Kaufman¹, K. Chapman², E. Leon², N. Ah Mew², A. Kroemer¹, R. Girlanda¹, J. Hawksworth¹, C. Matsumoto¹, T. Fishbein¹
¹MedStar Georgetown Transplant Institute, Washington, DC, ²Genetics, Children's National Hospital, Washington, DC
*Purpose: Background: Maple syrup urine disease (MSUD) is an inherited autosomal recessive metabolic disorder of amino acid metabolism, caused by a defect of the branched-chain…
2020 American Transplant Congress
Medication Knowledge Improves in Adolescent Kidney Transplant Patients with in Clinic Pharmacy Education
C. G. Peterson¹, E. Benefield², C. Heyrend²
¹Pediatric Nephrology, University of Utah, Salt Lake City, UT, ²Transplant Pharmacy, Primary Children's Hospital, Salt Lake City, UT
*Purpose: Successful transition of adolescent and young adult transplant recipients to adult-centered care remains challenging for transplant centers. This transition is associated with graft loss…
2020 American Transplant Congress
Pre-Transplant Detection of Anti-at1r Antibodies and Pediatric Kidney Transplantation Outcomes
K. Hitchman¹, C. Usenko², R. Hinojosa¹, D. Ranch¹
¹UT Health San Antonio, San Antonio, TX, ²University Health System, San Antonio, TX
*Purpose: Describe correlations between pre-transplant (PreTXP) presence of anti-angiotensin II receptor type 1 antibodies (AT1R Ab) and post-transplant (PostTXP) outcomes in a pediatric kidney transplant…
2020 American Transplant Congress
Current Status of Pre-Transplant Mortality in Pediatric Organ Transplantation
G. Mazariegos¹, E. Hsu², .. OPTN Pediatric Committee³
¹UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, ²Seattle Children's, Seattle, WA, ³UNOS, Richmond, VA
*Purpose: Although NOTA states that organ allocation policy must recognize differences between children and adults, and adopt criteria, policies, and procedures that address the unique…
2020 American Transplant Congress
Kidneys from Pediatric Donors Are Preferentially Allocated to Adult Highly Sensitized and Not to Pediatrics Under the New Kidney Allocation System (KAS)
D. Puliyanda¹, H. Pizzo¹, J. Garrison¹, S. Williamson², I. Kim², E. Huang²
¹Pediatric Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: In 12/2014, the new Kidney Allocation System (KAS) assigned allocation priority to highly sensitized (HS) recipients while maintaining access to donors for pediatric patients…
2020 American Transplant Congress
Influenza-Associated Hospitalizations in Pediatric Solid Organ Transplant Recipients
Z. Haddadin¹, V. Probst¹, H. Rahman¹, M. Hall², C. Thurm², N. Halasa¹, J. Godown³, D. E. Dulek¹
¹Pediatric Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, ²Children's Hospital Association, Lenexa, KS, ³Pediatric Cardiology, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Pediatric solid organ transplant (pSOT) recipients are at high risk for severe influenza virus infection. Data regarding the incidence, morbidity, mortality, and economic burden…
2020 American Transplant Congress
Outcome Disparities of Primary Pediatric Kidney Transplant Recipients by Payor, Ethnicity and Gender in the United States
S. M. Riad¹, S. Jackson², A. Matas³, S. Chinnakotla³, P. Verghese⁴
¹Medicine, University of Minnesota, Minneapolis, MN, ²Complex Care Analytics, Fairview Health Services, Minneapolis, MN, ³Surgery, University of Minnesota, Minneapolis, MN, ⁴Pediatric, University of Minnesota, Minneapolis, MN
*Purpose: Racial disparity outcome in pediatric kidney recipients has been reported. We sought to assess other predictors of outcomes disparities.*Methods: Using the SRTR database, between…