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Articles tagged "Pediatric"

  • 2021 American Transplant Congress

    A Comparison of Pediatric Intestine Transplant Between the Current Era (2015-2019) and the Peak Period (2002-2006)

    S. Horslen1, T. Weaver2, M. Skeans2

    1Seattle Children's Hospital, Seattle, WA, 2SRTR, Minneapolis, MN

    *Purpose: Demand for intestine transplants in children grew from its clinical inception in the late 1980s to a peak in 2007 of 111 small bowel-containing…
  • 2021 American Transplant Congress

    Impact of Once-Daily Extended-Release Tacrolimus Intrapatient Variability in Stable Adolescent and Young Adult Renal Transplant Recipients – 3 Year Results

    M. M. Chandran1, E. Blanchette1, J. Goebel2, M. Bock1

    1Children's Hospital Colorado, Denver, CO, 2Helen DeVos Children’s Hospital, Grand Rapids, MI

    *Purpose: Successful renal transplantation requires complex medication regimens that rely heavily on strict adherence to be effective. Variability in immunosuppression exposure, specifically tacrolimus, is associated…
  • 2021 American Transplant Congress

    Native Nephrectomy in Pediatric Kidney Transplant Recipients

    D. Yoeli1, A. Sater1, A. Peace1, M. E. Wachs1, M. Bock2, M. A. Adams1

    1Transplant Surgery, Children’s Hospital Colorado, Aurora, CO, 2Pediatric Nephrology, Children’s Hospital Colorado, Aurora, CO

    *Purpose: Data on native nephrectomy in children with renal disease requiring kidney transplantation is scarce. The aim of this study was to characterize demographics and…
  • 2021 American Transplant Congress

    Racial and Ethnic Disparities in Pediatric Kidney Transplantation – Has KAS Made a Difference?

    O. Charnaya1, S. Yu2, A. Goldberg3, J. Garonzik-Wang2, D. Segev2, P. Verghese4

    1Pediatrics, Johns Hopkins University, Baltimore, MD, 2Transplant Surgery, Johns Hopkins University, Baltimore, MD, 3University of Manitoba, Winninpeg, MB, Canada, 4Northwestern University Feinberg School of Medicine, Chicago, IL

    *Purpose: Racial and ethnic minority pediatric transplant candidates have known disparities in access to kidney transplantation. The Kidney Allocation System (KAS), implemented in 2014, was…
  • 2021 American Transplant Congress

    Adenovirus-Specific T Cells for Steering of Immunosuppression After Pediatric Kidney Transplantation in the Randomized Controlled Ivist Trial

    T. Ahlenstiel-Grunow1, X. Liu2, R. Schild3, J. Oh3, C. Taylan4, L. T. Weber4, H. Staude5, M. Verboom6, C. Schröder7, R. Sabau7, A. Großhennig2, L. Pape1

    1Pediatrics II, University Hospital of Essen, Essen, Germany, 2Institute of Biostatistics, Hannover Medical School, Hannover, Germany, 3Pediatric Nephrology, University Hospital Hamburg-Eppendorf, Hamburg, Germany, 4Pediatric Nephrology, University of Colgne, Köln, Germany, 5Pediatric Nephrology, University Hospital of Rostock, Rostock, Germany, 6Institute of Transfusion Medicine and Transplant Engineering, Hannover Medical School, Hannover, Germany, 7Institute for Clinical Pharmacology, Hannover Medical School, Hannover, Germany

    *Purpose: Pharmacokinetic monitoring alone is insufficient to estimate the intensity of immunosuppression after pediatric kidney transplantation (Tx). Levels of virus-specific T cells (Tvis) have been…
  • 2021 American Transplant Congress

    Longitudinal Studies of Blood Donor-derived Cell Free DNA (dd-cfDNA) Show Predictable Rise at Time of BK Viremia or Viruria in Pediatric Kidney Transplant Recipients (PKTx)

    R. Dandamudi1, H. Gu1, C. Goss1, S. Federman2, R. Woodward2, S. Dholakia2, L. Walther1, V. Dharnidharka1

    1Washington University in St Louis, St. Louis, MO, 2CareDx, Brisbane, CA

    *Purpose: Blood levels of dd-cfDNA elevate in various forms of kidney transplant injury, most notably used for detecting potential acute rejection. A few adult studies,…
  • 2021 American Transplant Congress

    Food Insecurity and Impact on Transplant Outcomes in Pediatric Kidney Transplant Recipients

    A. Moin, P. Verghese, R. Engen, D. Matossian

    Pediatric Nephrology, Lurie Children's Hospital, chicago, IL

    *Purpose: Food insecurity (FI), defined as inconsistent access to food or worry over shortage of food that prevents an active and healthy life, has not…
  • 2021 American Transplant Congress

    Kidney Paired Donation in Pediatrics: An Underused Opportunity?

    J. Smith1, M. Skeans2, R. Engen3, S. Bartosh4

    1Seattle Children's Hospital, Seattle, WA, 2SRTR, Minneapolis, MN, 3Lurie Children's Hospital, Chicago, IL, 4Univ of Wisconsin, Madison, WI

    *Purpose: Kidney paired donation (KPD) provides the opportunity for ABO-mismatched or HLA-incompatible pairs to receive a living donor kidney transplant. The superior graft survival among…
  • 2021 American Transplant Congress

    Mhealth Family Self-Management Intervention for Families of Transplanted Children

    S. M. Lerret1, R. White-Traut2, B. Medoff-Cooper3, S. I. Ahamed4, P. Simpson5, R. Schiffman6

    1Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, 2Children's Wisconsin, Milwaukee, WI, 3University of Pennsylvania, Philadelphia, PA, 4Department of Computer Science, Marquette University, Milwaukee, WI, 5Department of Biostatistics, Medical College of Wisconsin, Milwaukee, WI, 6University of Wisconsin Milwaukee, Milwaukee, WI

    *Purpose: Nearly 2,000 children undergo solid organ transplant in the US annually. In our previous research with transplant families, parents reported difficulty coping with the…
  • 2021 American Transplant Congress

    Longitudinal Studies of Blood Anellovirus DNA Prior to Acute Rejection or Major Infection Events in Pediatric Kidney Transplant Recipients (PKTx)

    R. Dandamudi, H. Gu, C. Goss, H. Gula, K. Wylie, V. Dharnidharka

    Washington University in St Louis, St. Louis, MO

    *Purpose: Blood levels of the ubiquitous but non-pathogenic anellovirus (AnV) taxa have been postulated to represent a biomarker of the overall state of immunosuppression after…
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