2022 American Transplant Congress
Why and How We Do Native Nephrectomy in Low Weight Pediatric Kidney Transplantation Patients
*Purpose: There is no consensus about optimal timing for native nephrectomy according to the primary indication of kidney transplantation (KTx) especially in pediatric population and…2022 American Transplant Congress
Disruption of B Cell Population is Associated with Increased Infections in Pediatric Transplant Recipients
Pediatrics, UCSD Rady Children's, San Diego, CA
*Purpose: Solid-organ transplant recipients are placed on long-term immunosuppression, preventing graft rejection but increasing the risk of infection. Pediatric transplant recipients are at increased risk…2022 American Transplant Congress
Surveillance of Donor-Derived Cell-Free DNA Throughout Treatment of Acute Rejection in Pediatric Renal Transplant Recipients
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a dynamic plasma biomarker for allograft rejection with limited data in pediatric renal transplant recipients and few reports describing…2022 American Transplant Congress
Pediatric Acute Liver Failure: Patient Factors Associated with Higher Mortality
*Purpose: Pediatric acute liver failure (PALF) is characterized by sudden onset deteriorating liver function, progressive coagulopathy, and hepatic encephalopathy in previously healthy children. The clinical…2022 American Transplant Congress
Single-Cell CyTOF Profiling of Pediatric Immune Responses to Organ Transplantation Reveals a Novel Subpopulation of T Cells Significantly Correlating with Graft Health
1Stanford University, Palo Alto, CA, 2Rho, Durham, NC, 3National Institutes of Health, Bethesda, MD
*Purpose: Solid organ transplant is lifesaving for children with end-stage heart, liver, or kidney disease. Protection of the transplanted organ from rejection requires long-standing immunosuppression.…2022 American Transplant Congress
Utility of Four-Point Mycophenolate Mofetil Testing in a Pediatric Kidney Transplant Population
Pediatric Nephrology, UCSF, San Francisco, CA
*Purpose: While there is randomized, multicenter data in adults that area under the time concentration curve (AUC) measurements for Mycophenolate Mofetil (MMF) can direct dosing…2022 American Transplant Congress
Abnormal B Cell Profile Associated with Inadequate Antibody Response to MRNA SARS-COV-2 Vaccine Can Be Overcome with a Third Vaccine Dose in Adolescent Kidney Transplant Recipients
Pediatrics, UCSD Rady Children's, San Diego, CA
*Purpose: mRNA SARS-CoV-2 vaccines are highly efficacious in the general population but have shown a diminished response in immunosuppressed adolescent kidney allograft recipients. We investigated…2022 American Transplant Congress
Impact of Arterial Reconstruction Technique on Hepatic Arterial Thrombosis in a Decade of Pediatric Liver Transplantation
*Purpose: Hepatic artery thrombosis (HAT) is a morbid and potentially fatal complication following pediatric liver transplantation (PLT). Previous registry studies have identified preoperative characteristics associated…2022 American Transplant Congress
A Cost Effectiveness Analysis of Adherence Promotion Strategies to Improve Rejection Rates in Adolescent Kidney Transplant Patients
*Purpose: In adolescents with a kidney transplant, non-adherence increases the risk of graft loss. Adherence promotion interventions improve adherence and rejection rates, but perceived cost…2022 American Transplant Congress
Utility of Urinary CTGF as a Biomarker of Progressive Allograft Dysfunction in Pediatric Renal Transplant Recipients
*Purpose: Previous reports from a number of studies indicate that renal allograft recipients who have inflammatory infiltrates within areas of interstitial fibrosis with tubular atrophy…
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