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Articles tagged "Pancreas"

  • 2016 American Transplant Congress

    Risk Factors for Early Readmission After Total Pancreatectomy with Islet Auto Transplantation.

    R. Shahbazov,1 N. Bashoo,2 G. Yoshimatsu,2 G. Saracino,2 F. Azari,1 N. Onaca,2 P. Kim,2 M. Levy.3

    1Charles O.Strikler Transplant Center, Department of Surgery, University of Virginia, Charlottesville, VA; 2Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX; 3Transplant Division, Virginia Commonwealth University, Richmond, VA.

    Introduction: Readmission after Total Pancreatectomy with Islet Auto Transplantation (TPIAT) is common, but no data is available on reasons for readmission and islet graft function.Aims:…
  • 2016 American Transplant Congress

    Surgical Techniques in Modified Multiorgan Transplantation.

    W. Ju, J. Lin, J. Zhou, M. Chen, A. Yang, D. Wang, Y. Ma, Z. Guo, M. Han, X. Wang, X. Zhu, X. He.

    Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Objective: Investigate the clinical efficacy of combined en-bloc liver-pancreas transplantation in patients with end stage liver disease and diabetes.Method: The clinical data of 19 cases…
  • 2016 American Transplant Congress

    FGF and Wnt Signaling in Pancreatic Progenitor and Beta-Cell Growth.

    S. Afelik,1 N. Yonan,1 B. Pool,2 J. Jensen,2 J. Oberholzer.1

    1Surgery, Division of Transplantation, University of Illinois, Chicago, IL; 2Stem Cell Biology and Regenerative Medicine, Cleveland Clinic Foundation, Cleveland, OH.

    Beta-cell replacement therapy offersa cure for diabetes, but this is limited by the lack of readilyavailable supply of cells. Our goal is generate enough beta-cells…
  • 2016 American Transplant Congress

    A Novel Microfluidic Device for Purification of Pancreatic Islet Preparations.

    W. Varhue,1 L. Langman,2 D. Bowers,3 S. Peirce-Cottler,3 N. Swami,1 K. Brayman.2

    1Electrical and Computer Engineering, University of Virginia, Charlottesville, VA; 2Surgery, University of Virginia, Charlottesville, VA; 3Biomedical Engineering, University of Virginia, Charlottesville, VA.

    Purpose: Demonstrate that novel continuous flow microfluidic designs can be utilized to remove contaminating acinar tissue and sort the purified islets, based on size and…
  • 2016 American Transplant Congress

    High Resolution Detection of Human Pancreatic Islet Damage During and After Isolation Procedure Using MicroRNAs.

    S. Prathab Balaji,1 M. Kanak,2 G. Yoshimatsu,1 C. Chang,1 M. Levy,2 M. Lawrence,1 P. Kim,3 N. Onaca,3 B. Naziruddin.3

    1Islet Cell Laboratory, Baylor Research Institute, Dallas, TX; 2Transplant Division, Department of Surgery, VCU Medical Center, Richmond, VA; 3Baylor Simmons Transplant Institute, Dallas, TX.

    Background: Pancreatic islets are subjected to stresses throughout isolation procedures that account for considerable variation in quality and yield. Multiparameter methods are needed to monitor…
  • 2016 American Transplant Congress

    IgM Treatment Successfully Prevents Type 1 Diabetes by Dysregulation of Pancreatic MicroRNAs with Immunomodulatory Roles.

    P. Chhabra, R. Gehrau, V. Mas, D. Bower, D. Maluf, K. Brayman.

    UVA, Charlottesville.

    Type 1 Diabetes (T1D) is hallmarked by beta-cells destruction. We aimed to identify specific pancreatic microRNAs (miRNA) as potential biomarkers for T1D prediction and diagnosis,…
  • 2015 American Transplant Congress

    Is BMI of 28 an Appropriate Cutoff for Simultaneous Pancreas Kidney Transplant in Type II Diabetes?

    E. Ahmed, D. Bruce, I. Carmody, A. Cohen, G. Loss, T. Reichman, J. Seal, H. Bohorquez.

    Multi-Organ Transplant Institute, Ochsner Clinic Foundation, New Orleans, LA.

    In simultaneous pancreas and kidney (SPK) transplantation, obesity has been reported to be associated with inferior survival and increased post-transplant complications. With implementation of the…
  • 2015 American Transplant Congress

    Reconsideration of Age Limits for Pancreas Transplantation

    J. Scalea, H. Sollinger, R. Redfield, M. Rizzari, D. Kaufman, J. Odorico.

    Div. of Transplantation, Dept. of Surgery, University of Wisconsin, Madison, WI.

    Introduction: Pancreas transplantation (PTx) remains the only strategy for reinstitution of long-term insulin production and outcomes have progressively improved. Yet, historically, centers have employed age-limits…
  • 2015 American Transplant Congress

    Increased Use of Donors After Cardiac Death (DCD) in Pancreas Transplantation: A Safe and Effective Way to Increase a Single Center Program Activity

    M. Marquez, G. Sapisochin, J. Laurence, A. Barbas, M. Dib, A. Norgate, M. Selzner, P. Greig, I. McGilvray, M. Cattral.

    Multi-Organ Transplant, University Health Network, Toronto, ON, Canada.

    The SRTR database shows that DCD donors are rarely used for pancreas transplantation in the USA (< 3% in 2010 -2012). This low rate likely…
  • 2015 American Transplant Congress

    Sirolimus Based Maintenance Immunosuppression in Pancreas Transplant Recipients

    A. Rajab, R. Pelletier, E. Elkhammas, G. Bumgardner, A. El-Hinnawi, M. Henry.

    Surgery, The Ohio State University, Columbus, OH.

    The present study evaluated the outcome of a Sirolimus based maintenance immunosuppressive protocol in pancreas transplant recipients. Between August 2003 and December 2013, a total…
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