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Articles tagged "Pancreas"

  • 2018 American Transplant Congress

    To Score a Pancreas, Stars Must Be Aligned

    A. Friedman, P. Bagavan, K. Delli Carpini.

    LiveOnNY, NY.

    Excellent medical care and readily accessible insulin preparations serve to require a very high quality of deceased donor pancreas organs accepted for transplantation. Improving, prevailing…
  • 2018 American Transplant Congress

    Hypoxia Results in Endoplasmic Reticulum Stress and Activation of the Unfolded Protein Response in Isolated Human Islets and Human Donor Pancreases

    B. Sandhu, M. Prendecki, N. Vallant, G. Rutter, C. Pusey, V. Papalois.

    Imperial College London, London, United Kingdom.

    Background: The Unfolded Protein Response (UPR) is activated as an adaptive response to endoplasmic reticulum (ER) stress, however if ER stress is not resolved, UPR…
  • 2018 American Transplant Congress

    Pancreas Decellularization Protocol – Comparison of Methods

    A. Berman, K. Karzynski, M. Serwanska-Swientek, N. Pilka, M. Klak, K. Kosowska, J. Cichon, F. Ambrozkiewicz, M. Wszola.

    Foundation of Research and Science Development, Otwock, Poland.

    Background: Whole organ decellularization is gaining a lot of popularity since its development in tissue engineering. It is a process which allows to create complex…
  • 2018 American Transplant Congress

    An Economic Analysis of the UK Pancreas Allocation Scheme

    K. Burke,1 S. Birch,2,3 T. Augustine.1

    1The Renal and Pancreas Transplantation Unit, Manchester Royal Infirmary, Manchester, United Kingdom; 2Centre for Health Economics, University of Manchester, Manchester, United Kingdom; 3Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada.

    Introduction: Economics provides input to decisions concerning the best use of available resources. In transplantation, limitations include organ availability and competing organ demands. This is…
  • 2017 American Transplant Congress

    Lessons Learned from Simultaneous Biopsies of Both Kidney and Pancreas Grafts in Recipients of Simultaneous Kidney-Pancreas Transplants.

    S. Parajuli, B. Astor, A. Djamali, R. Redfield, E. Arpali, D. Kaufman, J. Odorico, D. Mandelbrot.

    University of Wisconsin, Madison

    It is commonly assumed that in simultaneous kidney and pancreas (SPK) recipients the rejection of the two organs will be concordant. As a result, simultaneous…
  • 2017 American Transplant Congress

    Optimization of Pancreatic Islet-Like Clusters from hiPSCs for Cell Therapy in Type 1 Diabetes.

    G. Pettinato, P. Kyriazis, M. Thompson, M. Koulmanda, R. Fisher.

    Surgery, Beth Israel Deaconess Medical Center, Boston, MA

    IntroductionTreatment for Type 1 Diabetes (T1D) includes pancreas or islets of Langerhans transplantation. Pancreatic beta-like cells from differentiated human induced pluripotent stem cells (hiPSCs) offer…
  • 2017 American Transplant Congress

    Impact of Intensive Dosing of Mycophenolate on Pancreas Allograft Survival.

    J. Fose,1 K. Rolling,1 N. Menninga,1 G. Leverson,2 M. Jorgenson,1 J. Odorico,2 R. Robert.2

    1Pharmacy, UW Health, Madison, WI; 2Transplant Surgery, UW Health, Madison, WI

    Purpose: The primary objective was to evaluate the effect of mycophenolate (MPA) dicharge (DC) dose on pancreas allograft (PTX) survival. Secondary endpoints included patient survival…
  • 2017 American Transplant Congress

    Insulin Therapy in Pancreas Donors as a Predictor of Subsequent Transplant Outcome.

    I. Shapey,1 H. Khambalia,2 A. Summers,2 T. Augustine,2 M. Rutter,1 D. van Dellen.1

    1Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom; 2Department of Renal and Pancreas Transplantation, Central Manchester University Hospitals, Manchester, United Kingdom

    Introduction: Brain stem death causes high levels of systemic catecholamines and inflammation affecting all organs. These changes, and the routine use of high-dose corticosteroids in…
  • 2017 American Transplant Congress

    Kidney Re-Transplant Rate in Simultaneous Kidney Pancreas Transplant Recipients.

    M. McCormick, J. Luo, A. Hoffman.

    Transplant, University of Nebraska Medical Center, Omaha, NE

    Bladder drainage, although no longer the most commonly performed method for exocrine drainage of the pancreas, remains an option for patients undergoing simultaneous pancreas- kidney…
  • 2017 American Transplant Congress

    Send Diabetes on a Long Trip: The Pancreas Travels Well.

    J. Graham, M. Lubetzky, A. Chokechanachaisakul, M. Kinkhabwala, J. Rocca.

    Surgery, Montefiore Medical Center, Bronx, NY

    Pancreas transplantation (PTx) has been on a dramatic decline in the last decade. Numerous factors have contributed to the waning momentum seen in the early…
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