2018 American Transplant Congress
Human Pancreatic ECM Scaffolds for Islet Culture and Transplantation
Extracellular matrix (ECM) plays an important role through structural and biochemical interaction with cells. Tissue-specific ECM, attained through decellularization (decel), has been proposed in many…2018 American Transplant Congress
Consequences of Being Listed at a Small Pancreas Program
How pancreas transplant center (PTC) volume affects patient outcomes after listing is unclear. Low volumes may lengthen waiting times or limit access to transplantation. We…2018 American Transplant Congress
Enteric Conversion after Bladder-Drained Pancreas Transplantation: The Wisconsin Experience
Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
INTRODUCTION: In the early experience of pancreas transplantation, bladder drainage was favored. However, this often caused metabolic and infectious complications that necessitated conversion to enteric…2018 American Transplant Congress
Stress-Related Exosomal MicroRNA Biomarkers Released by Human Islets during Transplantation
1Baylor Scott & White Research Institute, Dallas; 2Baylor Simmons Transplant Institute, Dallas.
Purpose: Pancreatic islets release noncoding microRNAs (miRNAs) upon damage and stress during islet transplant procedures. In this study, we sought to identify miRNAs released by…2017 American Transplant Congress
Lessons Learned from Simultaneous Biopsies of Both Kidney and Pancreas Grafts in Recipients of Simultaneous Kidney-Pancreas Transplants.
University of Wisconsin, Madison
It is commonly assumed that in simultaneous kidney and pancreas (SPK) recipients the rejection of the two organs will be concordant. As a result, simultaneous…2017 American Transplant Congress
Optimization of Pancreatic Islet-Like Clusters from hiPSCs for Cell Therapy in Type 1 Diabetes.
Surgery, Beth Israel Deaconess Medical Center, Boston, MA
IntroductionTreatment for Type 1 Diabetes (T1D) includes pancreas or islets of Langerhans transplantation. Pancreatic beta-like cells from differentiated human induced pluripotent stem cells (hiPSCs) offer…2017 American Transplant Congress
Impact of Intensive Dosing of Mycophenolate on Pancreas Allograft Survival.
1Pharmacy, UW Health, Madison, WI; 2Transplant Surgery, UW Health, Madison, WI
Purpose: The primary objective was to evaluate the effect of mycophenolate (MPA) dicharge (DC) dose on pancreas allograft (PTX) survival. Secondary endpoints included patient survival…2017 American Transplant Congress
Insulin Therapy in Pancreas Donors as a Predictor of Subsequent Transplant Outcome.
Introduction: Brain stem death causes high levels of systemic catecholamines and inflammation affecting all organs. These changes, and the routine use of high-dose corticosteroids in…2017 American Transplant Congress
Kidney Re-Transplant Rate in Simultaneous Kidney Pancreas Transplant Recipients.
Transplant, University of Nebraska Medical Center, Omaha, NE
Bladder drainage, although no longer the most commonly performed method for exocrine drainage of the pancreas, remains an option for patients undergoing simultaneous pancreas- kidney…2017 American Transplant Congress
Send Diabetes on a Long Trip: The Pancreas Travels Well.
Surgery, Montefiore Medical Center, Bronx, NY
Pancreas transplantation (PTx) has been on a dramatic decline in the last decade. Numerous factors have contributed to the waning momentum seen in the early…
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