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Articles tagged "Pancreas"

  • 2018 American Transplant Congress

    Isolated Pancreas Transplantation: Does Rank List Position Matter for Imported Grafts?

    J. Adler, R. Redfield, D. Kaufman, J. Odorico.

    Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.

    INTRODUCTION: Pancreata are frequently not recovered or are discarded, resulting in a very low national utilization (~15%). There are many reasons why a transplant center…
  • 2018 American Transplant Congress

    Addressing the “Crisis” in Pancreas Transplant Volume Using a Multidisciplinary Approach

    J. Scalea, S. Bartlett, R. Barth.

    Surgery, University of Maryland, Baltimore, MD.

    Background: Due in part to the recently revised pancreas allocation system, patients who are listed for simultaneous pancreas and kidney (SPK) transplantation can be transplanted…
  • 2018 American Transplant Congress

    Insulin Use on Intensive Care Units as a Marker of beta-Cell Death in Brain Dead Pancreas Donors

    M. Shapey,1,2 A. Summers,2 J. O'Sullivan,2 P. Yianoullou,1,2 T. Augustine,2 M. Rutter,1 D. van Dellen.2

    1Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom; 2Department of Renal and Pancreatic Transplantation, Manchester University NHS Foundation Trust, Manchester, United Kingdom.

    IntroductionObjective methods for assessing the quality of pancreata for transplantation are urgently required. Donors after brain death (DBD) experience a catecholamine storm and systemic inflammation,…
  • 2018 American Transplant Congress

    Peri-Transplant Glycaemic Control as a Predictor of Pancreas Transplant Survival

    M. Shapey,1,2 R. Tan,1 H. Khambalia,2 C. Fullwood,2 P. Yianoullou,1,2 A. Summers,2 T. Augustine,2 M. Rutter,1 D. van Dellen.2

    1Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom; 2Department of Renal and Pancreatic Transplantaion, Manchester University NHS Foundation Trust, Manchester, United Kingdom.

    Introduction: The impact of peri-transplant glycaemic control on outcomes after pancreas transplantation is unknown. Our aims were to relate peri-transplant glycaemic control to survival and…
  • 2017 American Transplant Congress

    Optimization of Pancreatic Islet-Like Clusters from hiPSCs for Cell Therapy in Type 1 Diabetes.

    G. Pettinato, P. Kyriazis, M. Thompson, M. Koulmanda, R. Fisher.

    Surgery, Beth Israel Deaconess Medical Center, Boston, MA

    IntroductionTreatment for Type 1 Diabetes (T1D) includes pancreas or islets of Langerhans transplantation. Pancreatic beta-like cells from differentiated human induced pluripotent stem cells (hiPSCs) offer…
  • 2017 American Transplant Congress

    Impact of Intensive Dosing of Mycophenolate on Pancreas Allograft Survival.

    J. Fose,1 K. Rolling,1 N. Menninga,1 G. Leverson,2 M. Jorgenson,1 J. Odorico,2 R. Robert.2

    1Pharmacy, UW Health, Madison, WI; 2Transplant Surgery, UW Health, Madison, WI

    Purpose: The primary objective was to evaluate the effect of mycophenolate (MPA) dicharge (DC) dose on pancreas allograft (PTX) survival. Secondary endpoints included patient survival…
  • 2017 American Transplant Congress

    Insulin Therapy in Pancreas Donors as a Predictor of Subsequent Transplant Outcome.

    I. Shapey,1 H. Khambalia,2 A. Summers,2 T. Augustine,2 M. Rutter,1 D. van Dellen.1

    1Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom; 2Department of Renal and Pancreas Transplantation, Central Manchester University Hospitals, Manchester, United Kingdom

    Introduction: Brain stem death causes high levels of systemic catecholamines and inflammation affecting all organs. These changes, and the routine use of high-dose corticosteroids in…
  • 2017 American Transplant Congress

    Kidney Re-Transplant Rate in Simultaneous Kidney Pancreas Transplant Recipients.

    M. McCormick, J. Luo, A. Hoffman.

    Transplant, University of Nebraska Medical Center, Omaha, NE

    Bladder drainage, although no longer the most commonly performed method for exocrine drainage of the pancreas, remains an option for patients undergoing simultaneous pancreas- kidney…
  • 2017 American Transplant Congress

    Send Diabetes on a Long Trip: The Pancreas Travels Well.

    J. Graham, M. Lubetzky, A. Chokechanachaisakul, M. Kinkhabwala, J. Rocca.

    Surgery, Montefiore Medical Center, Bronx, NY

    Pancreas transplantation (PTx) has been on a dramatic decline in the last decade. Numerous factors have contributed to the waning momentum seen in the early…
  • 2017 American Transplant Congress

    The Association of Donor Vasoactive Drugs with Pancreas Transplant Graft Survival.

    I. Shapey,1 P. Yianoullou,2 A. Summers,2 T. Augustine,2 M. Rutter,1 D. van Dellen.2

    1Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom; 2Department of Renal and Pancreas Transplantation, Central Manchester University Hospitals, Manchester, United Kingdom

    Introduction: Vasoactive drugs (VaD) are commonly used to correct abnormal haemodynamics of organ donors in Intensive Care Units (ICU). VaDs can differentially affect insulin secretion…
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