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Articles tagged "Pancreas"

  • 2018 American Transplant Congress

    Human Pancreatic ECM Scaffolds for Islet Culture and Transplantation

    D. Tremmel, S. Sackett, A. Feeney, R. Maguire, J. Odorico.

    Univ of Wisconsin, Madison.

    Extracellular matrix (ECM) plays an important role through structural and biochemical interaction with cells. Tissue-specific ECM, attained through decellularization (decel), has been proposed in many…
  • 2018 American Transplant Congress

    Consequences of Being Listed at a Small Pancreas Program

    S. Niederhaus,1 M. Curry,2 A. Fox,2 J. Fridell,3 J. Odorico.4

    1Surgery, University of Maryland, Baltimore, MD; 2UNOS, Richmond, VA; 3Surgery, Indiana University, Indianapolis, IN; 4Surgery, University of Wisconsin, Madison, WI.

    How pancreas transplant center (PTC) volume affects patient outcomes after listing is unclear. Low volumes may lengthen waiting times or limit access to transplantation. We…
  • 2018 American Transplant Congress

    Enteric Conversion after Bladder-Drained Pancreas Transplantation: The Wisconsin Experience

    J. Adler, R. Redfield, D. Kaufman, J. Odorico, H. Sollinger.

    Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.

    INTRODUCTION: In the early experience of pancreas transplantation, bladder drainage was favored. However, this often caused metabolic and infectious complications that necessitated conversion to enteric…
  • 2018 American Transplant Congress

    Stress-Related Exosomal MicroRNA Biomarkers Released by Human Islets during Transplantation

    P. Saravanan,1 P. Nguyen,1 G. Yoshimatsu,1 C. Chang,1 C. Darden,1 R. Bhattacharjee,1 X. Wang,1 J. Gu,1 M. Lawrence,1 B. Naziruddin.2

    1Baylor Scott & White Research Institute, Dallas; 2Baylor Simmons Transplant Institute, Dallas.

    Purpose: Pancreatic islets release noncoding microRNAs (miRNAs) upon damage and stress during islet transplant procedures. In this study, we sought to identify miRNAs released by…
  • 2018 American Transplant Congress

    Isolated Pancreas Transplantation: Does Rank List Position Matter for Imported Grafts?

    J. Adler, R. Redfield, D. Kaufman, J. Odorico.

    Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.

    INTRODUCTION: Pancreata are frequently not recovered or are discarded, resulting in a very low national utilization (~15%). There are many reasons why a transplant center…
  • 2018 American Transplant Congress

    Addressing the “Crisis” in Pancreas Transplant Volume Using a Multidisciplinary Approach

    J. Scalea, S. Bartlett, R. Barth.

    Surgery, University of Maryland, Baltimore, MD.

    Background: Due in part to the recently revised pancreas allocation system, patients who are listed for simultaneous pancreas and kidney (SPK) transplantation can be transplanted…
  • 2018 American Transplant Congress

    Insulin Use on Intensive Care Units as a Marker of beta-Cell Death in Brain Dead Pancreas Donors

    M. Shapey,1,2 A. Summers,2 J. O'Sullivan,2 P. Yianoullou,1,2 T. Augustine,2 M. Rutter,1 D. van Dellen.2

    1Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom; 2Department of Renal and Pancreatic Transplantation, Manchester University NHS Foundation Trust, Manchester, United Kingdom.

    IntroductionObjective methods for assessing the quality of pancreata for transplantation are urgently required. Donors after brain death (DBD) experience a catecholamine storm and systemic inflammation,…
  • 2018 American Transplant Congress

    Peri-Transplant Glycaemic Control as a Predictor of Pancreas Transplant Survival

    M. Shapey,1,2 R. Tan,1 H. Khambalia,2 C. Fullwood,2 P. Yianoullou,1,2 A. Summers,2 T. Augustine,2 M. Rutter,1 D. van Dellen.2

    1Division of Diabetes, Endocrinology and Gastroenterology, University of Manchester, Manchester, United Kingdom; 2Department of Renal and Pancreatic Transplantaion, Manchester University NHS Foundation Trust, Manchester, United Kingdom.

    Introduction: The impact of peri-transplant glycaemic control on outcomes after pancreas transplantation is unknown. Our aims were to relate peri-transplant glycaemic control to survival and…
  • 2018 American Transplant Congress

    Pancreatic Graft Loss after Simultaneous Pancreas Kidney (SPK) Transplant within First 90 Days. Predictors beyond the Surgical Cause. A UNOS/OPTN Data Analysis

    H. Sharma, M. Abraham, J. Chen, D. Mikhail, S. Aquil, S. Patel, A. Skaro, V. McAlister, A. Sener, P. Luke.

    Multi-Organ Transplantation Unit, University of Western Ontario, London, ON, Canada.

    Background: Data on causal effects of variables to predict the early pancreatic graft loss in first 90 days is limited.Aim: To predict the early pancreatic…
  • 2018 American Transplant Congress

    Increased Risk of Early Graft Loss in Pancreas Transplant: A Retrospective Review of the UNOS Database

    E. Steen,1 C. Liu,2 E. Siskind,2 J. Ortiz.1

    1Surgery, University of Toledo Medical Center, Toledo, OH; 2Surgery, Inova Fairfax Hospital, Annandale, VA.

    Introduction: Pancreas transplant is an established cure for Type 1 diabetes. Nonetheless, early graft loss is not infrequent. We sought to analyze all of the…
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