2018 American Transplant Congress
Pancreatic Graft Loss after Simultaneous Pancreas Kidney (SPK) Transplant within First 90 Days. Predictors beyond the Surgical Cause. A UNOS/OPTN Data Analysis
Multi-Organ Transplantation Unit, University of Western Ontario, London, ON, Canada.
Background: Data on causal effects of variables to predict the early pancreatic graft loss in first 90 days is limited.Aim: To predict the early pancreatic…2018 American Transplant Congress
Increased Risk of Early Graft Loss in Pancreas Transplant: A Retrospective Review of the UNOS Database
Introduction: Pancreas transplant is an established cure for Type 1 diabetes. Nonetheless, early graft loss is not infrequent. We sought to analyze all of the…2018 American Transplant Congress
To Score a Pancreas, Stars Must Be Aligned
Excellent medical care and readily accessible insulin preparations serve to require a very high quality of deceased donor pancreas organs accepted for transplantation. Improving, prevailing…2018 American Transplant Congress
Hypoxia Results in Endoplasmic Reticulum Stress and Activation of the Unfolded Protein Response in Isolated Human Islets and Human Donor Pancreases
Imperial College London, London, United Kingdom.
Background: The Unfolded Protein Response (UPR) is activated as an adaptive response to endoplasmic reticulum (ER) stress, however if ER stress is not resolved, UPR…2018 American Transplant Congress
Pancreas Decellularization Protocol – Comparison of Methods
Foundation of Research and Science Development, Otwock, Poland.
Background: Whole organ decellularization is gaining a lot of popularity since its development in tissue engineering. It is a process which allows to create complex…2018 American Transplant Congress
An Economic Analysis of the UK Pancreas Allocation Scheme
Introduction: Economics provides input to decisions concerning the best use of available resources. In transplantation, limitations include organ availability and competing organ demands. This is…2018 American Transplant Congress
Human Pancreatic ECM Scaffolds for Islet Culture and Transplantation
Extracellular matrix (ECM) plays an important role through structural and biochemical interaction with cells. Tissue-specific ECM, attained through decellularization (decel), has been proposed in many…2018 American Transplant Congress
Consequences of Being Listed at a Small Pancreas Program
How pancreas transplant center (PTC) volume affects patient outcomes after listing is unclear. Low volumes may lengthen waiting times or limit access to transplantation. We…2018 American Transplant Congress
Enteric Conversion after Bladder-Drained Pancreas Transplantation: The Wisconsin Experience
Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
INTRODUCTION: In the early experience of pancreas transplantation, bladder drainage was favored. However, this often caused metabolic and infectious complications that necessitated conversion to enteric…2018 American Transplant Congress
Stress-Related Exosomal MicroRNA Biomarkers Released by Human Islets during Transplantation
1Baylor Scott & White Research Institute, Dallas; 2Baylor Simmons Transplant Institute, Dallas.
Purpose: Pancreatic islets release noncoding microRNAs (miRNAs) upon damage and stress during islet transplant procedures. In this study, we sought to identify miRNAs released by…
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