Articles tagged "Outcome"

2021 American Transplant Congress
Intravenous Immunoglobulin Protects Liver Allograft from Ischemia Reperfusion Injury in Human Liver Transplantation
S. Yokota, J. C. Alonso-Escalante, R. P. Tindall, K. R. Tabar, L. Machado, T. Uemura, N. L. Thai
Department of Surgery, Allegheny General Hospital, Pittsburgh, PA
*Purpose: Ischemia/reperfusion (I/R) injury following prolonged cold storage has a significant impact on early and late human liver transplantation (LTx) outcomes. Prevention of I/R injury…
2021 American Transplant Congress
Liver and Kidney Transplantation During the Covid-19 Pandemic Period: A Single Center Experience
M. Haberal¹, E. Karakaya¹, A. Akdur¹, E. Ayvazoglu Soy¹, F. Ozcay², E. Baskin³, S. Boyacioglu⁴, A. Torgay⁵, S. Yildirim¹, G. Moray¹, F. Yarbug Karakayali¹
¹Division of Transplantation, Department of General Surgery, Baskent University, Ankara, Turkey, ²Department of Pediatric Gastroenterology, Baskent University, Ankara, Turkey, ³Department of Pediatric Nephrology, Baskent University, Ankara, Turkey, ⁴Department of Gastroenterology, Baskent University, Ankara, Turkey, ⁵Department of Anaesthesiology, Baskent University, Ankara, Turkey
*Purpose: Introduction: Beginning of this year, when the Covid-19 pandemic has first started, it had the immediate effect of severely reducing living and deceased organ…
2021 American Transplant Congress
Allograft Discard Risk Index for Lung Transplantation
R. M. Reul, G. Loor, P. S. Garcha, A. A. Rana
Baylor College of Medicine, Houston, TX
*Purpose: The demand for donor lungs continues to outpace the supply, yet nearly 80% of donor lungs consented for lung transplantation (LTx) are discarded.*Methods: We…
2021 American Transplant Congress
Impact of Cypa5 Status on the Clinical and Financial Outcomes of Kidney Transplant
J. Obayemi¹, B. Keating², K. Lentine³, M. Schnitzler³, H. Xiao³, V. Dharnidharka⁴, D. Axelrod⁵
¹Univ of Michigan, Ann Arbor, MI, ²Univ of Pennsylvania, Philadelphia, PA, ³Saint Louis Univ, Saint Louis, MO, ⁴Washington Univ, Seattle, WA, ⁵Univ of Iowa, Iowa City, IA
*Purpose: Pharmacogenetic profiling of transplant recipients has demonstrated marked variation in the metabolism of immunosuppressive medications, particularly tacrolimus. Patients of African ancestry have been found…
2021 American Transplant Congress
Outcomes After Liver Transplantation With Steatotic Grafts: Redefining Acceptable Cutoffs for Moderately Steatotic Grafts
B. L. Da¹, J. Satiya², R. P. Heda³, Y. Jiang⁴, L. Lau⁵, A. Fahmy¹, A. Winnick¹, N. Roth¹, E. Grodstein¹, P. J. Thuluvath⁶, A. K. Singal⁷, T. D. Schiano⁸, L. W. Teperman¹, S. K. Satapathy¹
¹Liver Disease, Northwell Health, Manhasset, NY, ²Beth Israel Deaconess Medical Center, Boston, MA, ³Tulane Medical Center, Memphis, TN, ⁴The University of Memphis, Memphis, TN, ⁵Northwell Health, Manhasset, NY, ⁶University of Maryland School of Medicine, Baltimore, MD, ⁷Liver Disease, Avera McKenna University Health Center and Transplant Institute, Manhasset, NY, ⁸Icahn School of Medicine at Mount Sinai, New York City, NY
*Purpose: Graft macro-steatosis can predispose to worse graft survival. Our objective was to redefine acceptable cutoffs for graft steatosis using the national database.*Methods: Data of…
2021 American Transplant Congress
Pig Orthotopic Heart Transplantation (ohtx) in Baboons: Is an Acute Pulmonary Inflammatory Response the Key Problem?
A. Jagdale¹, D. Cleveland², M. Bikhet¹, J. Foote³, G. Walcott⁴, H. Iwase¹, T. Yamamoto¹, H. Hara¹, C. Hansens-Estruch¹, D. Ayares⁵, S. Litovsky⁶, L. Rhodes², W. Carlo⁷, J. Crawford², R. Dabal², S. Borasino², D. Cooper¹
¹Surgery, University of Alabama at Birmingham, Birmingham, AL, ²Cardiothoracic Surgery, Children's of Alabama, Birmingham, AL, ³Medicine and Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, AL, ⁴Medicine, University of Alabama at Birmingham, Birmingham, AL, ⁵Surgery, Revivicor, Blacksburg, VA, ⁶Pathology, University of Alabama at Birmingham, Birmingham, AL, ⁷Division of Pediatric Cardiology, Department of Pediatrics, University of Alabama at Birmingham, Children's of Alabama, Birmingham, AL
*Purpose: To investigate the mechanism of early cardio-pulmonary dysfunction after genetically engineered pig OHTx in baboons.*Methods: OHTx from pigs expressing different genetic modifications, α‐galactosyltransferase knockout…
2021 American Transplant Congress
The Co-Occurrence of Newly Developed HLA Donor Specific Antibody and Positive C3d/C4d Profiles Along with Immune Therapy Non-Compliance in Pediatric Heart Transplant Recipients is a High Risk Indicator for Patient Mortality
A. Zhang, C. Nasman, J. Allen, Y. Sun, D. Thomas, R. Rodriguez, C. Tan, G. Boyle
Cleveland Clinic Foundation Transplant Center, Cleveland, OH
*Purpose: Increasing evidence has implicated the deleterious effect of HLA donor specific antibody (DSA) in pediatric heart transplantation (PHTx). However, there are still insufficient research…
2021 American Transplant Congress
Covid vs Non Covid Pneumonia in Kidney Transplant Recipients
R. Prashar, N. Khoury, P. Shrivastava, S. Yeddula, T. Kitajima, E. Ulrich, M. Ramesh, A. Patel, S. Nagai, M. Samaniego-Picota
Henry Ford Hospital, Detroit, MI
*Purpose: Compare clinical characteristics and outcomes in kidney transplant recipients (KTRs) hospitalized with COVID vs Non COVID Pneumonia.*Methods: This is a retrospective case‐control study examining…
2021 American Transplant Congress
The Seattle Heart Failure Model is a Predictor of Mortality After Kidney Transplant in Patients with End Stage Renal Disease and Heart Impairment
A. Perez-Gutierrez¹, P. J. Bachul², D. N. Danz³, B. Juengel², M. Josephson², J. Fung², P. Witkowski², B. Chung⁴, Y. Becker²
¹Surgery, University of Chicago, Chicago, IL, IL, ²Surgery, University of Chicago, Chicago, IL, ³Economics, University of Pittsburgh, Pittsburgh, IL, ⁴Cardiology, University of Chicago, Chicago, IL
*Purpose: Cardiovascular disease is the main cause of mortality after kidney transplantation. Many patients with ESRD have heart failure that is attributed to fluid overload.…
2021 American Transplant Congress
Is There a Role for Pre-Operative Angiographic Kidney Embolization Prior to Allograft Nephrectomy?
M. Jacobs¹, R. Stratta¹, D. Harriman², A. Farney¹, J. Rogers¹, G. Orlando¹, A. Reeves-Daniel¹, C. Jay¹
¹Wake Forest Baptist Health, Winston Salem, NC, ²University of British Columbia, Vancouver, BC, Canada
*Purpose: To determine if morbidity associated with allograft nephrectomy (AN) of a failed or diseased kidney transplant (KT) is improved by pre-operative angiographic kidney embolization…