Articles tagged "Obesity"

2021 American Transplant Congress
Obesity Impacts Acute Rejection but Not Allograft Function Improvement in the Setting of Belatacept Conversion
D. Pierce, J. Benken, P. West-Thielke, I. Tzvetanov, E. Benedetti, A. Lichvar
University of Illinois at Chicago, Chicago, IL
*Purpose: There is limited data regarding belatacept conversion in obese patients as an alternative to calcineurin inhibitor (CNI) immunosuppression. Pharmacokinetic (PK) data suggests increasing clearance…
2020 American Transplant Congress
Optimal Recipient Selection and Surgical Complications in Dual Kidney Transplantation
S. Patel¹, S. Chang², R. Sussman³, R. Plews¹, R. Lopez-Soler⁴, D. Conti¹
¹Kidney and Pancreas Transplantation, Albany Medical Center, Albany, NY, ²Nephrology and Transplantation, University at Buffalo, Buffalo, NY, ³Center for Donation and Transplantation, Albany Medical Center, Albany, NY, ⁴Renal Transplant Program, Hines VA Medical Center, Chicago, IL
*Purpose: Kidney allocation has recently been modified to allow enhanced utilization of dual kidney transplants (DKT) to reduce organ discards. This study evaluates surgical complications…
2020 American Transplant Congress
Bariatric Surgery for Congestive Heart Failure Patients Improves Access to Transplantation and Long-Term Survival
R. A. Choudhury¹, G. Hoeltzel², H. B. Moore¹, H. Yaffe¹, D. Yoeli¹, K. R. Dumon³, K. D. Conzen¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA, ³Department of Surgery, University of Colorado Hospital, Philadelphia, PA
*Purpose: Obese patients with congestive heart failure (CHF) are often denied access to heart transplantation until they obtain significant weight loss to achieve a certain…
2020 American Transplant Congress
Lose Weight to Donate Program: Preliminary Results of a Program Intended to Optimize Obese Living Donor Liver Candidates
J. Rose¹, T. Seay², A. Pesch³, P. Vargas⁴, S. Pelletier⁴, J. Oberholzer⁴, C. Argo⁵, N. Goldaracena⁴
¹School of Medicine, University of Virginia Health System, Charlottesville, VA, ²Division of Transplantation, University of Virginia Health System, Charlottesville, VA, ³Radiology Department, University of Virginia Health System, Charlottesville, VA, ⁴Department of Surgery, Division of Transplantation, University of Virginia Health System, Charlottesville, VA, ⁵Department of Medicine-Gastroenterology, University of Virginia Health System, Charlottesville, VA
*Purpose: Living donation (LD) can alleviate organ shortage, but is limited by obesity compromising organ quality and donor safety. This study intends to assess the…
2020 American Transplant Congress
Pre-Transplant Bariatric Surgery is Associated with Increased Fungal Infection after Liver Transplant
M. Jorgenson¹, A. Gracon², B. Hanlon², G. Leverson², D. Al-Adra¹
¹UWHC, Madison, WI, ²UWMF, Madison, WI
*Purpose: The impact of pre-transplant (pre-TXP) bariatric surgery (BS) on outcomes after liver transplant (LTX) has not been completely elucidated. Roux-en Y gastric bypass (RYGB)…
2020 American Transplant Congress
Robot-Assisted versus Open Kidney Transplantation for Morbidly Obese Patients
S. D. Lee¹, B. Rawashdeh², E. K. McCracken², L. A. Cantrell³, A. Demirag², A. Agarwal², K. L. Brayman², S. J. Pelletier², J. Oberholzer²
¹Surgery, VCU Health, Richmond, VA, ²Surgery, University of Virginia, Charlottesville, VA, ³Obstetrics and Gynecology, University of Virginia, Charlottesville, VA
*Purpose: Obesity significantly impacts intraoperative and postoperative complications following kidney transplantation. Consequently, many centers deny access to transplantation in patients with a body mass index…
2020 American Transplant Congress
Transplant Outcomes, Risk Factors, and Regional Variation in Selection of Morbidly Obese Liver Transplant Candidates in the US
T. Lian¹, N. Kaur², J. Emamaullee², M. Lo³, P. Ender⁴, J. Kahn⁵, L. Sher²
¹Keck School of Medicine at USC, Los Angeles, CA, ²Department of Surgery, Keck School of Medicine at USC, Los Angeles, CA, ³Department of Preventative Medicine, Keck School of Medicine at USC, Los Angeles, CA, ⁴Statistical Consulting Group, University of California Los Angeles, Los Angeles, CA, ⁵Department of Medicine, Keck School of Medicine at USC, Los Angeles, CA
*Purpose: Body Mass Index (BMI) limits for liver transplant (LT) candidacy are controversial. We evaluated waitlist and post-LT outcomes, prognostic factors, and regional patterns of…
2020 American Transplant Congress
Comparing Weight-Based Dosing of Envarsus XR in Obese and Non-Obese Renal Transplant Recipients
N. Breslin, N. Jandovitz, V. Nair, M. Abate, L. Teperman
North Shore University Hospital, Manhasset, NY
*Purpose: Tacrolimus has a narrow therapeutic window and significant inter- and intra-patient variability leading to variations in drug concentration. The recommended initial weight-based dose of…
2020 American Transplant Congress
Basiliximab Induction in the Obese: One Size Does Fit All
A. D. Reticker¹, D. Choi¹, A. B. Lichvar¹, C. Kane², I. Tzvetanov³, E. Benedetti³, J. J. Benken¹
¹Pharmacy Practice, University of Illinois Hospital and Health Sciences System, Chicago, IL, ²Pharmacy, Northwestern Memorial Hospital, Chicago, IL, ³Surgery, University of Illinois Hospital and Health Sciences System, Chicago, IL
*Purpose: Surgical advancements allow more obese (BMI> 30 kg/m2) patients to receive a renal transplant. The original clinical and pharmacokinetic (PK) trials in transplantation immunosuppression…
2020 American Transplant Congress
Liver Transplant Recipients with BMI 40 to <50 kg/m² Have Excellent Patient and Graft Survival
K. Daniel, J. Hause, F. Osman, J. Mezrich, E. Spengler
University of Wisconsin School of Medicine and Public Health, Madison, WI
*Purpose: Obesity rates in the United States (US) have reached nearly 40%, which has led to an increasing proportion of liver transplant (LT) candidates with…

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