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Articles tagged "Obesity"

  • 2021 American Transplant Congress

    Nutrition, Body Habitus, and Food Insecurity, in Pediatric Kidney Transplant Recipients

    A. Wilkerson1, J. Figueroa1, C. Kang1, R. Garro2, M. Kamel1, R. P. George2

    1Emory University, Atlanta, GA, 2Emory University and Children's Healthcare of Atlanta, Atlanta, GA

    *Purpose: Appropriate nutrition and physical activity are critical for optimal post-transplant recovery and long term outcomes, especially in pediatric populations. Both malnutrition and obesity are…
  • 2021 American Transplant Congress

    Obesity is a Risk Factor for Progression to Kidney Transplant Waitlisting After Liver Transplantation

    B. Shelton1, B. Orandi1, K. Olthoff2, E. Pomfret3, K. Forde2, D. Sawinski2, M. Gray1, N. Ascher4, J. Locke1

    1University of Alabama at Birmingham, Birmingham, AL, 2University of Pennsylvania, Philadelphia, PA, 3University of Colorado School of Medicine, Aurora, CO, 4University of California San Francisco, San Francisco, CA

    *Purpose: Non-alcoholic steatohepatitis (NASH) has emerged as a leading cause of cirrhosis, and obesity-associated comorbid conditions, including renal disease have become more prevalent. Obesity predisposes…
  • 2021 American Transplant Congress

    Identification of Molecular Markers for Liver Cirrhosis by Single-nucleus Rna Sequencing

    C. Kuscu1, C. Kuscu1, M. Akram2, A. Shetty3, D. G. Maluf4, J. Eason1, V. Mas5

    1Surgery, James D Eason Transplat Institute, Memphis, TN, 2Surgery, Center for Biomedical Informatics, Memphis, TN, 3Surgery, Institute for Genome Sciences, School of Medicine, Baltimore, MD, 4Surgery, Program in Transplantation University of Maryland, Baltimore, MD, 5Surgery, Division of Surgical Science University of Maryland, Baltimore, MD

    *Purpose: Non-alcoholic fatty liver disease (NAFLD) is characterized by metabolic syndrome and the accumulation of fat in the liver cells (hepatocytes) leading to inflammation and…
  • 2021 American Transplant Congress

    State-level Trend in the Prevalence of Non-alcoholic Steatohepatitis for Liver Transplant Candidates in the United States, 2001-2017

    S. Chang1, M. Wang1, M. Pozo2, D. Ladner2, D. Borja-Cacho2

    1Washington University School of Medicine, Saint Louis, MO, 2Northwestern University, Chicago, IL

    *Purpose: As variation in the prevalence of obesity across states continues to grow, the prevalence of nonalcoholic steatohepatitis (NASH) is also rising. However, little is…
  • 2021 American Transplant Congress

    Recent Trends and Outcomes of Liver Transplantation for Non-alcoholic Steatohepatitis versus Alcohol Liver Disease in the United States: Obesity Might be Protective

    K. Okumura, I. Lee, H. Sogawa, G. Veillette, D. John, T. Diflo, R. Bodin, D. Wolf, S. Nishida

    Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY

    *Purpose: Nonalcoholic steatohepatitis (NASH) and alcohol liver disease (ALD) are rapidly growing indications for liver transplantation (LT). The recent trends and outcomes in NASH and…
  • 2021 American Transplant Congress

    Outcomes After Liver Transplantation With Steatotic Grafts: Redefining Acceptable Cutoffs for Moderately Steatotic Grafts

    B. L. Da1, J. Satiya2, R. P. Heda3, Y. Jiang4, L. Lau5, A. Fahmy1, A. Winnick1, N. Roth1, E. Grodstein1, P. J. Thuluvath6, A. K. Singal7, T. D. Schiano8, L. W. Teperman1, S. K. Satapathy1

    1Liver Disease, Northwell Health, Manhasset, NY, 2Beth Israel Deaconess Medical Center, Boston, MA, 3Tulane Medical Center, Memphis, TN, 4The University of Memphis, Memphis, TN, 5Northwell Health, Manhasset, NY, 6University of Maryland School of Medicine, Baltimore, MD, 7Liver Disease, Avera McKenna University Health Center and Transplant Institute, Manhasset, NY, 8Icahn School of Medicine at Mount Sinai, New York City, NY

    *Purpose: Graft macro-steatosis can predispose to worse graft survival. Our objective was to redefine acceptable cutoffs for graft steatosis using the national database.*Methods: Data of…
  • 2021 American Transplant Congress

    The Role of Histone Acetylation/methylation Mediated Epigenetic Modifications in the Pathogenesis of Non-alcoholic Steatohepatitis-associated Liver Carcinogenesis

    P. K. Rajan1, U. Utibe-Abasi1, J. D. Sanabria1, M. Banerjee2, G. Smith1, M. S. Schade1, J. Sanabria1, K. Sodhi1, S. Pierre2, Z. Xie2, J. I. Shapiro2, J. Sanabria1

    1Department of Surgery, Marshall University, Huntington, WV, 2Marshall Institute for Interdisciplinary Research (MIIR), Marshall University, Huntington, WV

    *Purpose: Hepatocellular carcinoma (HCC) is one of the most aggressive human cancers and is characterized by an acquisition of multiple abnormal phenotypes driven by epigenetic…
  • 2021 American Transplant Congress

    Obesity is Associated with Greater Gender Disparity in Access to Kidney Transplantation

    S. S. Sheikh, B. Orandi, P. MacLennan, H. Qu, R. M. Cannon, D. Anderson, M. Hanaway, S. Mehta, V. Kumar, R. Reed, J. Locke

    Surgery, University of Alabama at Birmingham, Birmingham, AL

    *Purpose: Obesity and female gender have been associated with decreased access to kidney transplant. We sought to use contemporary data to examine the likelihood of…
  • 2021 American Transplant Congress

    Utilization of Pre-Procurement Donor Liver Biopsy in Donation-after-circulatory-Death Liver Transplantation

    A. C. Bolognese1, N. Neidlinger1, C. Sparks2, A. Schneider2, A. M. D'Alessandro1, D. P. Foley1

    1Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2UW Organ and Tissue Donation, Madison, WI

    *Purpose: Careful selection of suitable DCD donor livers is critical to obtain optimal transplant outcomes. In order to identify potentially suitable livers prior to DCD…
  • 2021 American Transplant Congress

    Multistep Algorithm to Achieve Weight Loss Goal in Advanced Stage Obesity Kidney Transplant Candidates: A Single Center Preliminary Report

    A. Shah, J. Galpern, L. Castaldo, P. Touhy, M. Thomas, A. Aaron, M. Fruscione, L. Dageforde, N. Elias

    Transplant Surgery, Massachusetts General Hospital, Boston, MA

    *Purpose: Obesity causes and complicates glomerulonephritis and chronic kidney disease (CKD) leading to end stage renal disease (ESRD). Kidney Transplantation (KT) improves ESRD patients’ survival…
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