2021 American Transplant Congress
Obesity Impacts Acute Rejection but Not Allograft Function Improvement in the Setting of Belatacept Conversion
University of Illinois at Chicago, Chicago, IL
*Purpose: There is limited data regarding belatacept conversion in obese patients as an alternative to calcineurin inhibitor (CNI) immunosuppression. Pharmacokinetic (PK) data suggests increasing clearance…2021 American Transplant Congress
Application of Incisional Wound Vac to Decrease Wound Complications and Surgical Site Infections: A Single Center Pilot Project
University of Rochester Medical Center, Rochester, NY
*Purpose: Wound complications and surgical site infections (SSIs) are common but morbid complications of transplant in immunosuppressed patients. Kidney transplant patients who are obese, highly…2021 American Transplant Congress
Nutrition, Body Habitus, and Food Insecurity, in Pediatric Kidney Transplant Recipients
1Emory University, Atlanta, GA, 2Emory University and Children's Healthcare of Atlanta, Atlanta, GA
*Purpose: Appropriate nutrition and physical activity are critical for optimal post-transplant recovery and long term outcomes, especially in pediatric populations. Both malnutrition and obesity are…2021 American Transplant Congress
Obesity is a Risk Factor for Progression to Kidney Transplant Waitlisting After Liver Transplantation
*Purpose: Non-alcoholic steatohepatitis (NASH) has emerged as a leading cause of cirrhosis, and obesity-associated comorbid conditions, including renal disease have become more prevalent. Obesity predisposes…2021 American Transplant Congress
Identification of Molecular Markers for Liver Cirrhosis by Single-nucleus Rna Sequencing
*Purpose: Non-alcoholic fatty liver disease (NAFLD) is characterized by metabolic syndrome and the accumulation of fat in the liver cells (hepatocytes) leading to inflammation and…2021 American Transplant Congress
State-level Trend in the Prevalence of Non-alcoholic Steatohepatitis for Liver Transplant Candidates in the United States, 2001-2017
1Washington University School of Medicine, Saint Louis, MO, 2Northwestern University, Chicago, IL
*Purpose: As variation in the prevalence of obesity across states continues to grow, the prevalence of nonalcoholic steatohepatitis (NASH) is also rising. However, little is…2021 American Transplant Congress
Recent Trends and Outcomes of Liver Transplantation for Non-alcoholic Steatohepatitis versus Alcohol Liver Disease in the United States: Obesity Might be Protective
Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY
*Purpose: Nonalcoholic steatohepatitis (NASH) and alcohol liver disease (ALD) are rapidly growing indications for liver transplantation (LT). The recent trends and outcomes in NASH and…2021 American Transplant Congress
Outcomes After Liver Transplantation With Steatotic Grafts: Redefining Acceptable Cutoffs for Moderately Steatotic Grafts
*Purpose: Graft macro-steatosis can predispose to worse graft survival. Our objective was to redefine acceptable cutoffs for graft steatosis using the national database.*Methods: Data of…2021 American Transplant Congress
The Role of Histone Acetylation/methylation Mediated Epigenetic Modifications in the Pathogenesis of Non-alcoholic Steatohepatitis-associated Liver Carcinogenesis
*Purpose: Hepatocellular carcinoma (HCC) is one of the most aggressive human cancers and is characterized by an acquisition of multiple abnormal phenotypes driven by epigenetic…2021 American Transplant Congress
Obesity is Associated with Greater Gender Disparity in Access to Kidney Transplantation
Surgery, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Obesity and female gender have been associated with decreased access to kidney transplant. We sought to use contemporary data to examine the likelihood of…
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