Articles tagged "Obesity"

2016 American Transplant Congress
Gut Dysbiosis and Metabolic Disorders in Kidney Transplant Recipients.
M. Lecronier,¹ P. Tashk,¹ J. Aron-Wisnewsky,^2,3,4 E. Denamur,¹ O. Tenaillon,¹ B. Barrou,^4,5 J. Tourret.^1,4,5
¹IAME, UMR 1137, INSERM, Paris, France; ²Institute of Cardiometabolism and Nutrition, ICAN, Service de Nutrition, GH Pitié-Salpêtrière Charles Foix, AP-HP, Paris, France; ³UMR_S U1166, équipe NutriOmics, INSERM, Paris, France; ⁴Sorbonne Universités, Université Pierre et Marie Curie, Paris, France; ⁵AP-HP, Département d'Urologie, Néphrologie et Transplantation, GH Pitié-Salpêtrière Charles Foix, Paris, France.
IntroductionGut microbiota modifications (dysbiosis) have been observed in obese and/or diabetic patients. Kidney transplant recipients (KTR) are particularly exposed to the development of metabolic disorders,…
2016 American Transplant Congress
Visceral Adiposity Is Associated with Increased Recurrence of Hepatocellular Carcinoma Following Liver Transplantation.
A. Mathur, L. Boyangzi, M. Prince, J. Guarrera, B. Samstein, A. Griesemer, K. Halazun, T. Kato, J. Emond.
Abdominal Transplant, Columbia University, Ny, NY.
IntroductionObesity has become a worldwide epidemic. The number of patients with HCC undergoing Orthotopic liver transplant (OLT) is rising. Epidemiologic evidence suggests a link between…
2016 American Transplant Congress
Diabetes Mellitus Predicts Outcome in Obesity After Kidney Transplantation.
T. Schachtner,^1,2 M. Stein,² P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany.
Obesity has been associated with an increased risk of allograft loss and death from infection in kidney transplant recipients (KTRs). Therefore, previous studies suggested bariatric…
2016 American Transplant Congress
Muscle Function, Mass, and Quality in Obese Liver Transplant Candidates: Results from the Functional Assessment in Liver Transplantation (FrAILT) Study.
C. Wang, I. Lobach, J. Lai.
UCSF, San Francisco, CA.
Background: Sarcopenia, or severe loss of muscle mass, is common in cirrhotics and adversely affects quality of life and transplant outcomes. Obese liver transplant(LT) candidates…
2016 American Transplant Congress
Bile Acid Signaling Affects Metabolism and Prolongs Allograft Survival in Obese Recipients.
M. Quante, A. ElKhal, M. Seyda, J. Schuitenmaker, H. Uehara, S. Tullius.
Division of Transplant Surgery & Transplant Surgery Research Laboratory, Brigham and Women's Hospital / Harvard Medical School, Boston, MA.
Although obesity has been linked to impaired transplant outcomes, underlying mechanisms and consequences of obesity on alloimmunity are only poorly understood.Allogenic skin transplantations were performed…
2016 American Transplant Congress
Pre-Transplant Bariatric Surgery and One-Year Graft Loss Risk in Kidney Transplants.
G. Mour, J. Zhang, Z. Su, D. Taber, P. Mauldin, T. Srinivas.
MUSC, Charleston.
Background: Several centers recommend bariatric surgery (BS) pre-transplantation (pre-Tx) with arbitrary BMI cutoffs. The effects of BS on Tx outcome are unclear. We studied the…
2016 American Transplant Congress
Renal Transplant in Obese Recipients: Consideration of Donor and Recipient Factors Can Improve Outcomes.
P. Stahler, J. Mezrich, G. Leverson, D. Kaufman, H. Sollinger.
Division of Transplantation, University of Wisconsin-Madison, Madison, WI.
Background: Obesity rates in the transplant population are increasing. Previous studies are limited by small sample sizes, short-term follow up, and conflicting results. Factors including…
2016 American Transplant Congress
The Impact of Body Mass Index > 35 on Kidney Transplant Outcomes: A Systematic Review.
D. Walczak, E. Benedetti.
Organ Transplant, University of Illinois Hospital and Health Sciences System, Chicago, IL.
Background: The increased prevalence of obesity (BMI > 30) among adults in the United States over the last two decades is reflected in the number…
2016 American Transplant Congress
The Role of Obesity in Survival Outcomes of Liver Transplant Recipients with High MELD Score.
S.-H. Chang,¹ N. Carlsson,¹ X. Liu,² J. Wellen,³ J. Hagopian,⁴ T. Horwedel,⁴ T. Alhamad.⁵
¹Division of Public Health Sciences, Department of Surgery, Washington University in St. Louis, St. Louis; ²Division of Biostatistics, Washington University in St. Louis, St. Louis; ³Department of Surgery, Washington University in St. Louis, St. Louis; ⁴Department of Pharmacy, Barnes Jewish Hospital, St. Louis; ⁵Renal Division, Washington University, St. Louis.
Background:Obesity has become an epidemic in the United States. More than one third of adults are obese, defined as having body mass index (BMI) greater…
2016 American Transplant Congress
Resolution of Donor Non-Alcoholic Fatty Liver Disease Following Liver Transplantation.
A. Posner,¹ W. Twaddell,² S. Hanish,² D. Bruno,² W. Hutson,² L. Hebert,² R. Barth,² J. LaMattina.²
¹University of Maryland School of Medicine, Baltimore, MD; ²Division of Transplantation, University of Maryland School of Medicine, Baltimore, MD.
Purpose: Severe and moderate degrees of donor liver steatosis have traditionally limited the transplantation of these organs. The natural history of successfully transplanted livers with…