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Articles tagged "Obesity"

  • 2017 American Transplant Congress

    Can We Successfully Overcome Obesity as a Barrier for Kidney Transplantation?

    K. Zorbas,1 S. Karhadkar,1 S. Rao,2 K. Lau,1 I. Lee,2 A. Gillespie,2 S. Constantinescu,2 A. Karachristos,1 A. Di Carlo.1

    1Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, PA; 2Nephrology, Temple University, Philadelphia, PA

    Obesity is a significant barrier for kidney transplantation (KT) with higher rates of denial for listing and longer listing to transplantation interval. We examined the…
  • 2017 American Transplant Congress

    An Analysis of Tacrolimus XL Dosing in Obese Kidney Transplant Recipients.

    N. Jasiak, J. Thielke, K. Progar, J. Chen, C. Adams, E. Benedetti, P. West-Thielke.

    Univ of Ill, Chicago

    Background:Tacrolimus extended-release (XL) is utilized in many immunosuppressive regimens post-kidney transplantation. Current dosing recommendation for the XL formulation in renal transplant (txp) is 0.15 mg/kg/day…
  • 2017 American Transplant Congress

    Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Dosing.

    D. Hesselink,1 L. Andrews,2 B. de Winter,2 J. Tang,3 N. Shuker,2 R. Bouamar,2 R. van Schaik,4 B. Koch,2 T. Van Gelder.1

    1Internal Medicine, Erasmus MC, Rotterdam, Netherlands; 2Hospital Pharmacy, Erasmus MC, Rotterdam, Netherlands; 3Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China; 4Clinical Chemistry, Erasmus MC, Rotterdam, Netherlands

    Bodyweight-based dosing of tacrolimus (Tac) is considered standard care, even though the available evidence is thin. An increasing proportion of transplant recipients is overweight, prompting…
  • 2017 American Transplant Congress

    Access to Simultaneous Pancreas and Kidney Transplant (SPK) Should Not Be Restricted to BMI > 28.

    M. Laftavi, A. Gruessner, V. Whittaker, Z. Acun, O. Pankowycz, R. Gruessner.

    SUNY Upstate Medical University, Syracuse, NY

    Background: Currently, UNOS guidelines require that uremic, insulin-dependent type 1 diabetic patients have a body mass index (BMI) < 28m/kg2 in order to be eligible…
  • 2017 American Transplant Congress

    Impact of Body Mass Index and Waist Circumference in Kidney Transplant Recipients.

    J.-E. Serre, M. Huet, I. Scwarc, V. Pernin, M. Le Quintrec, G. Mourad.

    Department of Nephrology, University Hospital of Montpellier, Montpellier, France, Metropolitan

    Introduction: The impact of obesity defined by a body mass index [BMI] > 30 kg/m[sup2] on kidney allograft outcomes remains controversial. The use of BMI…
  • 2017 American Transplant Congress

    Impact of Bariatric Surgery on Risk of Organ Rejection Among Solid Organ Transplant Recipients.

    M. Soghikian, D. Gregory, J. Wilcox, A. Shetty, D. Ladner, L. VanWagner.

    Medicine, Northwestern University, Chicago, IL; Surgery, Northwestern University, Chicago, IL

    Background: Obesity is a common condition that contributes to organ failure. Bariatric surgery is an effective surgical therapy for obesity and has been performed both…
  • 2017 American Transplant Congress

    Muscle Mass Is Predictive of Mortality in Obese Renal Transplant Patients.

    J. Souweine,1,3 M. Le Quintrec,1 I. Szwarc,1 V. Pernin,1 G. Mourad,1 J. Cristol,2,3 J. Serre.1

    1Nephrology, University Hospital of Montpellier, Montpellier, France; 2Biochemistry, University Hospital of Montpellier, Montpellier, France; 3PhyMedExp, UMR CNRS 9214, INSERM U1046, University Hospital of Montpellier, Montpellier, France

    Introduction: The impact of obesity (body mass index [BMI] > 30 kg/m[sup2]) on kidney allograft outcomes is controversial. Recent studies found that obesity does not…
  • 2016 American Transplant Congress

    The Effect of Body Mass Index on Lung Transplant Outcomes.

    M. Kashem,1 A. Shiose,1 J. Abraham,1 N. Dean,1 S. Breves,1 F. Cordova,2 N. Patel,2 T. Yoshizumi,1 G. Criner,2 Y. Toyoda.1

    1Division of Cardiovascular Surgery, Temple University, Philadelphia, PA; 2Department of Thoracic Medicine and Surgery, Temple University, Philadelphia, PA.

    Background: Lung transplant (LTx) has the potential to effectively extend the life expectancy for patients with end-stage lung disease. Both high and low body mass…
  • 2016 American Transplant Congress

    Outcomes of Donor Nephrectomy (DN) in the Obese.

    O. Serrano,1 A. Bangdiwala,2 D. Vock,3 E. Minja,1 W. Payne,1 T. Dunn,1 S. Chinnakotla,1 E. Finger,1 T. Pruett,1 A. Matas,1 R. Kandaswamy.1

    1Surgery, Univ. of Minnesota, Minneapolis, MN; 2Biostatistics and Bioinformatics Core, Masonic Cancer Center, Minneapolis, MN; 3Biostatistics, Univ. of Minnesota, Minneapolis, MN.

    PURPOSE: In an effort to address the critical organ shortage and rising obesity rates, the criteria for live kidney donation (LKD) have been expanded to…
  • 2016 American Transplant Congress

    Outcomes in Obese Renal Transplant Recipients Using High versus Low-Dose Thymoglobulin.

    N. Jasiak,1 C. Stromayer,1 J. Thielke,1 J. Chen,2 J. Chen,1 B. Talon,1 R. Rubin-Tobar,1 E. Benedetti,2 P. West-Thielke.1,2

    1Pharmacy, University of Illinois, Chicago; 2Transplant Surgery, University of Illinois, Chicago, IL.

    Background: Dosing of rabbit anti-thymocyte globulin (rATG) induction in renal transplant recipients is highly variable by transplant center. Optimizing rATG dose becomes extremely important for…
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