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Articles tagged "Obesity"

  • 2017 American Transplant Congress

    An Analysis of Tacrolimus XL Dosing in Obese Kidney Transplant Recipients.

    N. Jasiak, J. Thielke, K. Progar, J. Chen, C. Adams, E. Benedetti, P. West-Thielke.

    Univ of Ill, Chicago

    Background:Tacrolimus extended-release (XL) is utilized in many immunosuppressive regimens post-kidney transplantation. Current dosing recommendation for the XL formulation in renal transplant (txp) is 0.15 mg/kg/day…
  • 2017 American Transplant Congress

    Overweight Kidney Transplant Recipients Are at Risk of Being Overdosed Following Standard Bodyweight-Based Tacrolimus Dosing.

    D. Hesselink,1 L. Andrews,2 B. de Winter,2 J. Tang,3 N. Shuker,2 R. Bouamar,2 R. van Schaik,4 B. Koch,2 T. Van Gelder.1

    1Internal Medicine, Erasmus MC, Rotterdam, Netherlands; 2Hospital Pharmacy, Erasmus MC, Rotterdam, Netherlands; 3Laboratory Medicine, West China Hospital of Sichuan University, Chengdu, China; 4Clinical Chemistry, Erasmus MC, Rotterdam, Netherlands

    Bodyweight-based dosing of tacrolimus (Tac) is considered standard care, even though the available evidence is thin. An increasing proportion of transplant recipients is overweight, prompting…
  • 2017 American Transplant Congress

    Access to Simultaneous Pancreas and Kidney Transplant (SPK) Should Not Be Restricted to BMI > 28.

    M. Laftavi, A. Gruessner, V. Whittaker, Z. Acun, O. Pankowycz, R. Gruessner.

    SUNY Upstate Medical University, Syracuse, NY

    Background: Currently, UNOS guidelines require that uremic, insulin-dependent type 1 diabetic patients have a body mass index (BMI) < 28m/kg2 in order to be eligible…
  • 2017 American Transplant Congress

    Impact of Body Mass Index and Waist Circumference in Kidney Transplant Recipients.

    J.-E. Serre, M. Huet, I. Scwarc, V. Pernin, M. Le Quintrec, G. Mourad.

    Department of Nephrology, University Hospital of Montpellier, Montpellier, France, Metropolitan

    Introduction: The impact of obesity defined by a body mass index [BMI] > 30 kg/m[sup2] on kidney allograft outcomes remains controversial. The use of BMI…
  • 2017 American Transplant Congress

    Impact of Bariatric Surgery on Risk of Organ Rejection Among Solid Organ Transplant Recipients.

    M. Soghikian, D. Gregory, J. Wilcox, A. Shetty, D. Ladner, L. VanWagner.

    Medicine, Northwestern University, Chicago, IL; Surgery, Northwestern University, Chicago, IL

    Background: Obesity is a common condition that contributes to organ failure. Bariatric surgery is an effective surgical therapy for obesity and has been performed both…
  • 2017 American Transplant Congress

    Muscle Mass Is Predictive of Mortality in Obese Renal Transplant Patients.

    J. Souweine,1,3 M. Le Quintrec,1 I. Szwarc,1 V. Pernin,1 G. Mourad,1 J. Cristol,2,3 J. Serre.1

    1Nephrology, University Hospital of Montpellier, Montpellier, France; 2Biochemistry, University Hospital of Montpellier, Montpellier, France; 3PhyMedExp, UMR CNRS 9214, INSERM U1046, University Hospital of Montpellier, Montpellier, France

    Introduction: The impact of obesity (body mass index [BMI] > 30 kg/m[sup2]) on kidney allograft outcomes is controversial. Recent studies found that obesity does not…
  • 2017 American Transplant Congress

    Training for Transplant: Frailty Assessment and Optimization in Kidney Transplant Candidates.

    M. Mrdutt, D. Doherty, S. Tanner, J. Lappin.

    Surgery, Scott & White Medical Center, Temple, TX

    Purpose: To design and implement a frailty assessment and optimization program addressing potential modifiable risk factors that would ordinarily disqualify patients from kidney and/or pancreas…
  • 2017 American Transplant Congress

    Obesity Is an Important Factor in Deceased but Not Living Donor Kidney Transplants.

    A. Asderakis, A. Ilham, U. Khalid, R. Chavez.

    Cardiff Transplant Unit, University Hospital of Wales, Cardiff, United Kingdom

    Introduction There is an increasing obesity among potential kidney transplant recipients. We had in the past shown that obesity did increase the wound infection rate,…
  • 2017 American Transplant Congress

    The Associations Between Body Mass Index and Kidney Transplant Outcomes Are Mediated by Weight-Adjusted Immunosuppression Dosing.

    K. Flabouris,1,2 S. Chadban,1,3,4 M. Ladhani,1,3,5 M. Cervelli,6 P. Clayton.1,2,6

    1Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry, Adelaide, Australia; 2School of Medicine, University of Adelaide, Adelaide, Australia; 3Sydney Medical School, University of Sydney, Sydney, Australia; 4Department of Renal Medicine, Royal Prince Alfred Hospital, Sydney, Australia; 5Department of Renal Medicine, Lyell McEwin Hospital, Adelaide, Australia; 6Central Northern Adelaide Renal and Transplantation Service, Royal Adelaide Hospital, Adelaide, Australia

    Purpose: High body mass index (BMI) is associated with acute rejection after kidney transplantation. We hypothesised that weight-adjusted immunosuppression dosing is a contributing factor. We…
  • 2017 American Transplant Congress

    Carotid Intima-Media Thickness and Myocardial Strain in Pediatric Kidney Transplant Recipients.

    K. Sgambat, S. Clauss, M. Lasota, A. Moudgil.

    Children's National, Washington DC

    A prospective controlled longitudinal study was conducted to investigate determinants of carotid intima-media thickness (CIMT) and myocardial strain in children after kidney transplant (Tx).Methods: 42…
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