ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "non-heart-beating"

  • 2017 American Transplant Congress

    Objective Assessment of Graft Metabolism and Function During Ex Vivo Liver Perfusion.

    J. Echeverri,1 S. Cleland,2 M. Kaths,1 I. Linares,1 R. Roizales,1 N. Goldaracena,1 D. Kollmann,1 M. Hamar,1 P. Urbanellis,1 S. Ganesh,1 O. Adeyi,3 D. Grant,1 N. Selzner,4 M. Wasowicz,2 M. Selzner.1

    1Multi-Organ Transplant Program, Department of Surgery, University of Toronto - Toronto General Hospital, Toronto, ON, Canada; 2Multi-Organ Transplant Program, Department of Anesthesia, University of Toronto - Toronto General Hospital, Toronto, ON, Canada; 3Multi-Organ Transplant Program, Department of Pathology, University of Toronto - Toronto General Hospital, Toronto, ON, Canada; 4Multi-Organ Transplant Program, Department of Medicine, University of Toronto - Toronto General Hospital, Toronto, ON, Canada

    During EVLP no objective perfusion parameters have been found to predict outcome after transplantation.Methods: Livers with 4grades of injury were perfused for 4 hours and…
  • 2017 American Transplant Congress

    Donor Age > 50 Years and CIT Longer Than 18 Hour Are Independent Risk Factors for One Year Graft Survival in Renal Transplant Form Uncontrolled Donors After Circulatory Death (uDCD).

    M. Molina, E. Gutierrez, E. Gonzalez, E. Morales, J. Cabrera, A. Andres.

    Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain; Nephrology Department, Hospital Evangelico y Hospital Militar, Montevideo, Uruguay

    Introduction: Kidneys transplantations (KT) from uDCD have higher ischemia injury. It develops in higher primary non-function and delayed graft function, lower graft survival and worst…
  • 2017 American Transplant Congress

    Simultaneous Liver-Kidney Transplants Using Donation After Cardiac Death Donors Long Term Outcomes Not Inferior to Brain Dead Donors.

    J. Alvarez-Casas, S. Sultan, J. Scalea, K. McClure, J. LaMattina, D. Bruno, S. Hanish, R. Barth.

    University of Maryland School of Medicine, Baltimore, MD

    Background:The Simultaneous use of both Liver and Kidney from the same DCD donor has become controversial with some authors advocating that DCD organs should not…
  • 2017 American Transplant Congress

    Warm Ischemic Time as an Additive Predictor of Graft Survival in KDPI/KDRI Era of Kidneys from Donors After Cardiac Death: A Single-Center Experience Over Three Decades.

    M. Kusaka,1 Y. Kubota,1 H. Takahashi,2 H. Sasaki,1 M. Takenaka,1 N. Fukami,1 T. Kenmochi,3 R. Shiroki,1 K. Hoshinaga.1

    1Urology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan; 2Division of Medical Statistics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan; 3Organ Transplant Surgery, Fujita Health University School of Medicine, Toyoake, Aichi, Japan

    It is important to predict the outcome of grafts prior to kidney transplantation and establish an appropriate allocation system, particularly to consider expanded criteria donors…
  • 2017 American Transplant Congress

    Kidney Re-Transplantation (KRTx) from Donation After Cardiocirculatory Death (DCD)-Standard Criteria Donors (SCD).

    M. Khan, B. Alradawna, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, A. Palanisamy, M. Gautreaux, W. Doares, S. Kaczmorsky, R. Stratta.

    Transplant, Wake Forest Baptist Medical Center, Winston Salem, NC

    Donation after cardiac death (DCD) donor kidneys increase the organ pool but use in kidney retransplantation (KRTx) has been questioned due to higher rates of…
  • 2017 American Transplant Congress

    Prophylactic Therapy Against Multidrug-Resistant Acinetobacter baumannii Contamination of Preservation Solution in Renal Transplantation: A Single Center Experience.

    R. Wang, J. Zhou, J. Wu.

    Kidney Disease Center, the First Affiliated Hospital, Zhejiang University, Hangzhou, China

    Objectives: Rapidly increased multiple drug resistant (MDR) gram negative bacilli like Acinetobacter baumannii (AB) become the main pathogen in ICU nowdays. Our study is intended…
  • 2017 American Transplant Congress

    Normothermic Regional Perfusion of Donors Following Circulatory Death Improves Outcomes in Liver Transplantation.

    E. Mowlem,1 L. Randle,2 C. Fear,1 K. Crick,1 S. Messer,4 S. Large,4 A. Butler,3 C. Watson.3

    1Cambridge Transplant Unit, Addenbrookes Hospital, Cambridge, United Kingdom; 2OrganOx Ltd, Oxford, United Kingdom; 3Dept of Surgery, University of Cambridge, Cambridge, United Kingdom; 4Papworth Hospital, Cambridge, United Kingdom

    Introduction: Donation after Circulatory Death (DCD) provides 23% of UK livers for transplantation, but such transplants are associated with more primary graft function and early…
  • 2017 American Transplant Congress

    The Performance of Four Tools for the Prediction of Potential for Organ Donation After Cardiac Death in Neurocritical Patients: A Prospective, Multicenter, Observational Study.

    Z. Guo,1 G. Xu,1 P. Schroder,2 M. Manyalich,3 X. He,1 G. Chen.1

    1Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; 2Department of Surgery, Duke University Medical Center, Durham; 3Transplant Procurement Management-Donation & Transplantation institute Foundation, Barcelona, Spain

    Background Successful donation after circulatory death (DCD) requires identification of patients dieing within limited time after withdrawal of life-sustaining treatment (WLST). We aimed to compare…
  • 2017 American Transplant Congress

    A Humanized Anti-CD47 Monoclonal Antibody Therapy Alleviates Ischemia-Reperfusion Injury of Porcine Renal Allografts Donated After Cardiac Death.

    M. Xu,1 B. Banan,1 X. Wang,1 D. Chirumbole,1 B. Rabe,1 S. Garcia-Aroz,1 D. Nayak,1 Z. Zhang,1 J. Jia,1 G. Upadhya,1 J. Gaut,2 P. Manning,3 Y. Lin,1 W. Chapman.1

    1Department of Surgery, Washington University School of Medicine, St. Louis; 2Department of Pathology and Immunology, Washington University School of Medicine, St. Louis; 3Tioma Therapeutics, Inc, St. Louis

    PURPOSE: This study investigated whether the blockade of the CD47 signaling pathway, which is involved in vascular endothelial nitric oxide regulation, reduces ischemia-reperfusion injury (IRI)…
  • 2017 American Transplant Congress

    A Novel Technique to Increase Donor Utilization: Our Experience Using High-Dose Tissue Plasminogen Activator Flush in Donation-After-Cardiac-Death Donors for Liver Transplantation.

    J. Graham, K. Lorenzen, S. Bellemare, M. Kinkhabwala, J. Rocca.

    Surgery, Montefiore Medical Center, Bronx, NY

    The utilization of donation-after-cardiac-death (DCD) livers remains generally low. Strategies to address the perceived liabilities associated with DCD organs could influence their utilization in a…
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