Date: Monday, May 1, 2017
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
Introduction: Kidneys transplantations (KT) from uDCD have higher ischemia injury. It develops in higher primary non-function and delayed graft function, lower graft survival and worst renal function than ideal donors. However a optimal use of kidney from uDCD help us to reduce the otherwise, large renal transplant waiting list.
Aim: To identify donor and procurement factors of uDCD and their influence with one-year graft survival.
Material and Methods: We included all patients that received a KT form uDCD with at least one year of follow-up. We reviewed variables of uDCD and their influence in one-year death censored graft survival .
Results: We included 264 KT from uDCD. Donor characteristics were: age 44±9.7 years old, 87% (231) males, weight 80.5±11.5 kilograms, body mass index 26.8±3.2 kg/m2 and serum creatinine 1.3±0,4 mg/dl. 79.2% (209) of KT had delayed graft function. One-year graft survival was 90%. 27 grafts were lost in the first year, 67% of them (18) were non-primary function. Multivariable study is shown in the table.
|Donor > 50 years old||2.3 (1.1-5) P=0.02||2.4 (1.1-5.3) p=0.03|
|Body mass index > 30 kg/m2||2.2 (0.6-8.3) p=0.22||–|
|Cold ischemia time > 18 hours||2.7 (1.1-6.5) p=0.02||2.8 (1.2-6.7) p=0.02|
Conclusion: Kidney transplantations from uDCD have a good 1-year survival. A good choice of the donor avoiding older donors and a reduction of cold isquemia time to prevent additional ischemic damage could improve the one year graft survival in this KT from DCDD programs.
CITATION INFORMATION: Molina M, Gutierrez E, Gonzalez E, Morales E, Cabrera J, Andres A. Donor Age > 50 Years and CIT Longer Than 18 Hour Are Independent Risk Factors for One Year Graft Survival in Renal Transplant Form Uncontrolled Donors After Circulatory Death (uDCD). Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:Molina M, Gutierrez E, Gonzalez E, Morales E, Cabrera J, Andres A. Donor Age > 50 Years and CIT Longer Than 18 Hour Are Independent Risk Factors for One Year Graft Survival in Renal Transplant Form Uncontrolled Donors After Circulatory Death (uDCD). [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/donor-age-50-years-and-cit-longer-than-18-hour-are-independent-risk-factors-for-one-year-graft-survival-in-renal-transplant-form-uncontrolled-donors-after-circulatory-death-udcd/. Accessed December 5, 2019.
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