2016 American Transplant Congress
Unexpected Early Calcineurin Inhibitor Nephrotoxicity in Pediatric Kidney Transplant Recipients.
Background: Calcineurin inhibitors effectively suppress the recipient immune response and facilitate early success in kidney transplantation. However, these drugs are potent nephrotoxins and contribute to…2016 American Transplant Congress
Early Proteomic Predictors of Late Chronic Kidney Disease in Liver Transplant Recipients.
1Northwestern, Chicago; 2Baylor, Dallas.
Background: A high proportion of patients develop chronic kidney disease (CKD) after liver transplantation (LT). However, the ability to better select patients for nephroprotective interventions…2015 American Transplant Congress
microRNA-494 Promotes Cyclosporine-Induced Nephrotoxicity and Epithelial to Mesenchymal Transition By Inhibiting PTEN
Purpose: A major complication associated with cyclosporine (CsA) treatment is nephrotoxicity. MicroRNAs (miRs) have been shown to play an important role in various pathological conditions,…2015 American Transplant Congress
Spironolactone Prevents Calcineurin Inhibitors Toxicity in Renal Allografts. Preliminary Report
Nephrology, Hospital General "Dr Miguel Silva", Morelia, Michoacan, Mexico.
Introduction: Calcineurin inhibitors (CI) introduction was a transcendental event in the transplant medicine history. Actually, CI are considered the cornerstone in the immunosuppression treatment because…2015 American Transplant Congress
Renal Function Difference Between Anti-Hepatitis B Immunoglobulin(HBIG) Monotherapy and HBIG Combined With Entecavir in Liver Recipients
Background: To reduce the HBV reinfection after liver transplantation, anti-hepatitis B immunoglobulin (HBIG) alone or combination with antiviral nucleotide analogues are usually used regimen. However,…2015 American Transplant Congress
Pharmacogenetic Variation in Renal Calcineurin Inhibitor (CNI) Metabolism and the Response of Allograft-Derived Proximal Tubule Cells
Background: Multiple studies have demonstrated the importance of genetic variation in CYP3A5 and ABCB1 for calcineurin inhibitor (CNI) disposition and CNI-related nephrotoxicity. Renal CNI metabolism…2015 American Transplant Congress
Moderate Rejection Episode of Face Transplant After mTOR Conversion to Preserve Renal Function
1University of Maryland School of Medicine, Baltimore; 2New York Medical University, New York City.
Face and hand vascularized composite allografts (VCA) have demonstrated durable graft survivals with conventional immunosuppression but with the appearance of renal dysfunction. Management strategies that…
American Transplant Congress abstracts