ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Multicenter studies"

  • 2017 American Transplant Congress

    Extraction Time During Liver Retrieval Impairs Survival After Transplantation.

    I. Jochmans,1 S. Fieuws,2 I. Tieken,3 U. Samuel,3 J. Pirenne.1

    1Abdominal Transplantation, UZ Leuven, Leuven, Belgium; 2ICBSB, UZ Leuven, Leuven, Belgium; 3Eurotransplant, Leiden, Netherlands

    During donor hepatectomy, despite topic cooling to 10-20[deg]C, the liver still sustains warm ischemia that might be harmful.We investigated the relationship between extraction time (ET)…
  • 2017 American Transplant Congress

    Desensitization versus Deceased Donor Kidney Transplantation: What to Choose When Both Become Available?

    B. Orandi,1 X. Luo,2 J. Garonzik-Wang,2 R. Montgomery,3 D. Segev.2

    1UCSF, San Francisco; 2Johns Hopkins, Baltimore; 3NYU, New York

    Kidney allocation system changes have improved deceased donor kidney transplant (DDKT) access for highly sensitized patients. For patients with a willing live donor but requiring…
  • 2017 American Transplant Congress

    Detection of Shared and Distinct Gene Expression Signatures in Tissue and Urine During Acute Rejection of Kidney Grafts.

    K. Keslar,1 A. Zmijewska,2 J. Chen,2 K. Newell,3 P. Heeger,4 R. Mannon,2 R. Fairchild.1

    1Department of Immunology, Cleveland Clinic, Cleveland, OH; 2Department of Medicine, Division of Nephrology, University of Alabama at Birmingham, Birmingham, AL; 3Department of Surgery, Emory University, Atlanta, GA; 4Department of Medicine, Translational Transplant Research Center, Icahn School of Medicine at Mount Sinai, New York, NY

    A major goal of the Clinical Trials in Organ Transplantation (CTOT) studies is the identification of biomarkers that predict or diagnose acute graft rejection in…
  • 2017 American Transplant Congress

    Immunosuppression and Graft Rejection in Living-Related HLA-Identical Renal Transplantation.

    R. Ossman,1 M. Jamme,1 P. Galichon,1 A. Hertig,1 B. Moulin,2 C. Legendre,3 E. Morelon,4 J.-L. Taupin,5 L. Rostaing,6 E. Rondeau.1

    1Urgences Néphrologiques et Transplantation, Hôpital Tenon, RADOVFULL Study Group, Université Pierre et Marie Curie, Paris, France; 2Néphrologie et Transplantation, Hôpital Civil, Strasbourg, France; 3Néphrologie et Transplantation, Hôpital Necker-Enfants Malades, Université Paris Descartes, Paris, France; 4Néphrologie et Transplantation, Hôpital Edouard Herriot, Université de Lyon, Lyon, France; 5Laboratoire d'Histocompatibilité, Hôpital Saint-Louis, Université Paris Diderot, Paris, France; 6Néphrologie et Transplantation d'Organes, Université Paul Sabatier, Toulouse, France

    Purpose: We aimed to describe the immunosuppressive regimens and graft rejection rates in living-related HLA-identical (LR HLAid) renal transplantation.Methods: We performed a retrospective multicenter analysis…
  • 2017 American Transplant Congress

    Transplantation of Organs from Donors with Hepatitis C: The Potential to Substantially Increase Transplant Activity.

    P. Trotter,1,2 M. Robb,2 I. Ushiro-Lumb,2 J. Powell,3 C. Watson,1 J. Bradley,1 J. Neuberger.2,4

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom; 2Organ Donation and Transplantation, National Health Service Blood and Transplant, Bristol, United Kingdom; 3Hepatic-Pancreatico-Biliary Surgical Services and Edinburgh Transplant Unit, Royal Infirmary Edinburgh, Edinburgh, United Kingdom; 4The Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom

    Introduction. Organs from hepatitis C virus positive (HCV+ve) donors are commonly declined for transplantation because of the risk of disease transmission, but new direct acting…
  • 2017 American Transplant Congress

    Mutations in Influenza A Virus and Clinical Implications in Transplant Recipients.

    V. Ferreira,1 A. Humar,1 E. Cordero,2 E. Blumberg,3 S. Husain,1 J. Kalpoe,4 M. Multicenter Influenza Group, D. Kumar.1

    1UHN, Toronto, Canada; 2REIPI, Seville, Spain; 3UPenn, Philadelphia; 4LUMC, Leiden, Netherlands

    Background: Organ and hematopoietic stem cell transplant (HSCT) recipients are predisposed to complications of influenza infection and as such may constitute an important source of…
  • 2017 American Transplant Congress

    Clinical Risk Factors for Bronchiolitis Obliterans Syndrome (BOS) in Lung Transplant Recipients (LTRs): Results of an International Cohort Study.

    N. Law,1 B. Hamandi,1 C. Fegbeutel,2 F. Silveira,3 E. Verschuuren,4 P. Ussetti,5 P. Chin-Hong,6 A. Solé,7 C.-L. Holmes-Liew,8 E. Billaud,9 P. Grossi,10 O. Manuel,11 D. Levine,12 R. Barbers,13 D. Hadjiliadis,14 L. Singer,1 S. Husain.1

    1University Health Network, Toronto, ON, Canada; 2Hannover Medical School, Hannover, Germany; 3University of Pittsburgh, Pittsburgh, PA; 4University Medical Center Groningen, University of Groningen, Groningen, Netherlands; 5Hospital Puerta de Hierro, Madrid, Spain; 6University of California, San Francisco, CA; 7University and Polytechnic Hospital La Fe, Universidad de Valencia, Valencia, Spain; 8Royal Adelaide Hospital, Adelaide, Australia; 9APHP Hopital Européen G Pompidou, Paris, France; 10University of Insubria, Varese, Italy; 11University Hospital of Lausanne, Lausanne, Switzerland; 12University of Texas Health Science Center San Antonio, San Antonio, TX; 13KECK Medical Center of University of Southern California, Los Angeles, CA; 14University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, PA

    Introduction:Bronchiolitis obliterates syndrome (BOS) is a major impediment in the long term survival of LTRs. The main objective of this study was to identify infectious…
  • 2017 American Transplant Congress

    Results of the Initial Phase of the Portable Organ Care System (OCS™) Liver PROTECT Pivotal Trial.

    J. Markmann,1 M. Ghobrial,3 J. Magliocca,4 A. Demetris,5 M. Abouljoud.2

    1Department of Surgery-Division of Transplantation, Massachusetts General Hospital, Boston, MA; 2Transplant Institute and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI; 3Sherrie & Alan Conover Center for Liver Disease & Transplantation, Houston Methodist Hospital, Houston, TX; 4Division of Transplant Surgery Department of Surgery, The Emory Transplant Center, Atlanta, GA; 5Department of Transplant Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA

    PurposeThe OCS Liver PROTECT Trial is a prospective, international, randomized controlled trial to evaluate the impact of using portable ex-vivo warm, oxygenated blood perfusion using…
  • 2016 American Transplant Congress

    NanoString Detection of Gene Signatures in Urine During Acute Cellular Rejection of Kidney Grafts.

    K. Keslar,1 A. Zmijewska,2 J. Andriga,2 K. Newell,3 R. Mannon,2 P. Heeger,4 R. Fairchild.1

    1Cleveland Clinic, Cleveland; 2UAB, Birmingham; 3Emory, Atlanta; 4MSSM, New York.

    Considerable effort has focused on identification of gene expression patterns that may assist in diagnosis of acute cellular rejection. The NanoString platform offers a novel…
  • 2016 American Transplant Congress

    Factors Associated with Increased Risk of MELD Progression Among a Large Population of Patients with Cirrhosis and an Initial Low MELD Score (<15).

    K. Atiemo, L. Zhao, A. Skaro, L. VanWagner, S. Goel, A. Kho, B. Ho, R. Kang, S. Montag, J. Holl, M. Abecassis, D. Ladner.

    Northwestern University, Chicago.

    AimsLiving donor liver transplantation (LDLT) is an underutilized resource. Timely identification of patients with cirrhosis and a low MELD who's MELD score is likely to…
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