Articles tagged "Multicenter studies"

2022 American Transplant Congress
Delta Changes in Donor-Derived Cell-Free DNA (dd-cfDNA) Complement the Donor Fraction in Kidney Transplant Surveillance
A. Wiseman¹, M. Jagadeesan², G. Gupta³, V. Rao⁴, M. Narayanan⁵, N. Agrawal⁶, G. Shekhtman⁶, Y. Fu⁶, K. Pinney⁶, S. Anand⁷
¹Centura Health, Denver, CO, ²George Washington University, Washington, DC, ³Virginia Commonwealth University, Richmond, VA, ⁴Medical University of South Carolina, Charleston, SC, ⁵Baylor Scott and White, Austin, TX, ⁶CareDx, Brisbane, CA, ⁷Intermountain Healthcare, Murray, UT
*Purpose: Delta changes in dd-cfDNA levels over time may identify patients with evolving alloimmune injury, providing complementary information to the donor fraction. We explored the…
2022 American Transplant Congress
Third Dose of SARS-CoV-2 mRNA Vaccines Significantly Increases Delta (B.1.617.2) Variant Anti-Spike Antibody Levels in Kidney Transplant Recipients
A. Al Jurdi¹, R. B. Gassen¹, T. Borges¹, I. T. Lape¹, L. Morena¹, O. Efe¹, Z. Solhjou², R. El Fekih², C. Kotton¹, J. Azzi², L. Riella¹
¹Massachusetts General Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, MA
*Purpose: Emerging SARS-CoV-2 variants may be associated with a higher risk of breakthrough infections compared to wild-type (WT) virus in kidney transplant recipients (KTRs). The…
2022 American Transplant Congress
Ex Vivo End Ischemic Hypothermic Oxygenated Perfusion (hope) Versus Static Cold Storage Prior To Liver Transplantation – Preliminary Results Of The Bridge To Hope Pivotal Multicenter Randomized Controlled Clinical Trial On The Safety And Effectiveness Of The Vitasmart Liver Machine Perfusion System (clinicaltrials.gov: Nct05045794)
D. J. Reich¹, A. Schlegel², M. Rizzari³, D. Foley⁴, M. DeVera⁵, W. Chapman⁶, G. Roll⁷, A. Saharia⁸, C. Quintini⁹, S. Florman¹⁰, S. Merani¹¹, S. Mao¹², A. Pinna¹³, M. Akoad¹⁴, C. Kubal¹⁵, S. Alexopoulos¹⁶, H. Bohorquez¹⁷
¹Drexel University, Philadelphia, PA, ²Careggi U, Florence, Italy, ³Henry Ford, Detroit, MI, ⁴U Wisconsin, Madison, WI, ⁵Loma Linda, Loma Linda, CA, ⁶Washington U, Saint Louis, MO, ⁷UCSF, SF, CA, ⁸Methodist, Houston, TX, ⁹Cleveland Clinic, Cleveland, OH, ¹⁰Mount Sinai, NY, NY, ¹¹U Nebraska, Omaha, NE, ¹²Mayo, Jacksonville, FL, ¹³Cleveland Clinic, Weston, FL, ¹⁴Lahey, Burlington, MA, ¹⁵Indiana U, Indianapolis, IN, ¹⁶Vanderbilt, Nashville, TN, ¹⁷Ochsner, New Orleans, LA
*Purpose: Ex vivo end ischemic hypothermic oxygenated machine perfusion (HOPE) is a simple technique to improve liver transplant (LT) results and the donor shortage. HOPE…
2022 American Transplant Congress
Technology Enabled And Molecular Monitoring Of The Allograft And Transplant Recipient Study
N. Sulejmani¹, D. Axelrod², S. Dholakia¹, S. Shah³
¹CareDx, South San Francisco, CA, ²University of Iowa, Iowa City, IA, ³University of Cincinnati, Cincinnati, OH
*Purpose: With the widespread availability of smart mobile devices, mobile health (mHealth) provides the opportunity to reach wide array of patients. Readmission rates as high…
2022 American Transplant Congress
A Novel Prospective Validation Trial Of Multiple Blood-based RNA Signature Assays Pre And Post Kidney Transplant To Predict Rejection
L. Gallon¹, P. O'Connell², A. Chang³, M. Donovan⁴
¹Northwestern Univ, Chicago, IL, ²Westmead Inst, Sydney, Australia, ³Univ of Chicago, Chicago, IL, ⁴Verici Dx, Franklin, TN
*Purpose: The accuracy and utility of clinically defined and analytically validated predictive biomarkers in kidney transplantation is limited. We leveraged prior feasibility blood-RNA studies to…
2022 American Transplant Congress
Outcomes of COVID-19 in Solid Organ Transplant Recipients in Canada 2020-2021: A Prospective, Multicenter Cohort Study
V. G. Hall¹, G. Alahmadi², J. T. Solera², T. Marinelli², H. Cardinal³, G. Prasad⁴, S. A. De Serres⁵, D. Isaac⁶, R. Mainra⁷, C. Lamarche⁸, R. Sapir-Pichhadze⁹, S. Gilmour¹⁰, A. Humar², D. Kumar²
¹University Health Network/Toronto General Hospital, Toronto, ON, Canada, ²UHN, Toronto, ON, Canada, ³UMontreal, Montreal, QC, Canada, ⁴StMH, Toronto, ON, Canada, ⁵Laval U, Quebec, QC, Canada, ⁶UCalgary, Calgary, AB, Canada, ⁷USaskatchewan, Saskatoon, SK, Canada, ⁸HMR, Montreal, QC, Canada, ⁹McGill U, Montreal, QC, Canada, ¹⁰SCH, Edmonton, AB, Canada
*Purpose: To understand the outcomes and changes in disease severity of COVID-19 in Solid Organ Transplant (SOT) recipients over time in the context of therapeutic…
2022 American Transplant Congress
Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients: Practice Patterns, Report from the Paramour “Pediatric Renal AMR Outcomes” Study
N. Hayde¹, K. Twombley², I. Ashoor³, R. Engen⁴, L. Harshman⁵, R. Zahr⁶, C. Peterson⁷, S. McEwen⁸, A. Jain⁹, R. Garro¹⁰, M. Kallash¹¹, A. Mansuri¹², D. Puliyanda¹³
¹Montefiore Medical Center, Bronx, NY, ²Medical University of South Carolina, Charleston, SC, ³LCMCHealth, New Orleans, LA, ⁴Pediatrics, University of Wisconsin Madison, Madison, WI, ⁵University of Iowa Children's Hospital, Iowa City, IA, ⁶Le Bonheur Children's Hospital, Nashville, TN, ⁷University of Utah, Salt Lake City, UT, ⁸University of Minnesota, Minneapolis, MN, ⁹Wayne State, Troy, MI, ¹⁰Emory Universtiy, Atlanta, GA, ¹¹The Ohio State, Columbus, OH, ¹²Augusta University Medical Center, Augusta, GA, ¹³Cedars-Sinai Med Ctr, West Hollywood, CA
*Purpose: There is insufficient data on children with AMR in the literature, and the optimal therapy for AMR is not well defined. We aim to…
2022 American Transplant Congress
Associated Factors to Physical Inactivity of Kidney Transplant Patients: Subproject of ADHERE Brazil Multicenter Study
E. S. Sertorio¹, F. A. Colugnati¹, K. Denhaerynck², S. De Smet³, J. O. Medina⁴, M. M. Reboredo⁵, S. De Geest², H. Sanders-Pinheiro¹, T. ADHERE BRAZIL Study team¹
¹Nephrology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, ²Department of Public Health, Institute of Nursing Science, University of Basel, Basel, Switzerland, ³Transplant Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, ⁴Nephrology, Hsopital do Rim, Federal University of São Paulo, São Paulo, Brazil, ⁵Pneumology, Federal University of Juiz de Fora, Juiz de Fora, Brazil
*Purpose: Even though regular physical activity is a current recommendation for kidney transplant recipients (KTR), results from ADHERE Brazil study revealed a high prevalence of…
2022 American Transplant Congress
BMI Trajectory and Attributable Risk of New Onset Hypertension Among Obese Living Kidney Donors
R. D. Reed¹, M. C. McLeod¹, P. A. MacLennan¹, V. Kumar¹, S. E. Brooks¹, A. G. Maynor¹, L. A. Stanford¹, G. A. Baker¹, C. A. Schinstock², J. R. Silkensen³, G. R. Roll⁴, D. L. Segev⁵, B. J. Orandi¹, C. E. Lewis⁶, J. E. Locke¹
¹Surgery, University of Alabama at Birmingham, Birmingham, AL, ²Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ³Medicine, Hennepin County Medical Center, Minneapolis, MN, ⁴Surgery, University of California San Francisco, San Francisco, CA, ⁵Surgery, Johns Hopkins University, Baltimore, MD, ⁶Epidemiology, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Obesity increases hypertension risk in general and living kidney donor populations. Risk attributable to donation in the context of obesity and whether that risk…
2022 American Transplant Congress
Outcomes of SARS-CoV-2 Infection in Unvaccinated Compared with One or Two Dose Vaccinated Solid Organ Transplant Recipients: A Multicenter, Matched Cohort Study
V. G. Hall¹, G. Alahmadi², J. T. Solera², T. Marinelli², H. Cardinal³, G. Ramesh Prasad⁴, S. A. De Serres⁵, D. Isaac⁶, R. Mainra⁷, C. Lamarche⁸, R. Sapir-Pichhadze⁹, S. Gilmour¹⁰, J. Matelski², A. Humar², D. Kumar²
¹University Health Network/Toronto General Hospital, Toronto, ON, Canada, ²UHN, Toronto, ON, Canada, ³Department of Medicine, UMontreal, Montreal, QC, Canada, ⁴Kidney Transplant Program, St. Michael's Hospital, Toronto, ON, Canada, ⁵Transplantation Unit, Renal division, Laval University, Quebec, QC, Canada, ⁶Division of Transplant Medicine, University of Calgary, Calgary, AB, Canada, ⁷University Health Center of Saskatchewan, Saskatoon, SK, Canada, ⁸Hôpital Maisonneuve-Rosemont Research Institute, Montreal, QC, Canada, ⁹McGill University, Montreal, QC, Canada, ¹⁰Stollery Children's Hospital, Edmonton, AB, Canada
*Purpose: It is unknown if vaccine breakthrough COVID-19 infections are milder or as severe as infections in unvaccinated solid organ transplant (SOT) recipients.*Methods: We performed…

1
2
3
…
13
Next Page »