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Articles tagged "Monitoring"

  • 2017 American Transplant Congress

    Impact of mTOR-Inhibition on Tolerance-Induction Following Heart Transplantation.

    M.-T. Dieterlen, K. Klaeske, J. Fischer, J. Hahn, K. Jawad, J. Garbade, F. Mohr, S. Lehmann.

    Clinic for Cardiac Surgery, Heart Center Leipzig, Leipzig, Germany

    Introduction: The mammalian target of rapamycin (mTOR) is a central regulator of the immune system and therefore one target of immunosuppressive drug therapy. Tolerance-inducing properties…
  • 2016 American Transplant Congress

    NanoString Detection of Gene Signatures in Urine During Acute Cellular Rejection of Kidney Grafts.

    K. Keslar,1 A. Zmijewska,2 J. Andriga,2 K. Newell,3 R. Mannon,2 P. Heeger,4 R. Fairchild.1

    1Cleveland Clinic, Cleveland; 2UAB, Birmingham; 3Emory, Atlanta; 4MSSM, New York.

    Considerable effort has focused on identification of gene expression patterns that may assist in diagnosis of acute cellular rejection. The NanoString platform offers a novel…
  • 2016 American Transplant Congress

    Impact of Ethnicity on Tacrolimus Trough/Dose Ratios Following Solid Organ Transplantation.

    A. Santeusanio, A. Owusu-Obeng, J. Jeff.

    Mount Sinai Hospital, New York.

    Objective: to assess tacrolimus dosing requirements based upon ethnicity in order to help guide future decisions regarding dosage initiation and titration among Hispanic and African…
  • 2016 American Transplant Congress

    Comparison of Actual versus Goal Tacrolimus Levels Post Cardiothoracic Transplant.

    E. Milas, I. Feurer, C. Truscott, J. Gray, N. Wilson, S. Bala, T. Dreher, M. Wigger, M. Steele, A. Shah, E. Lambright, D. Hanto.

    Vanderbilt Transplant Center, Nashville, TN.

    BackgroundAlthough target tacrolimus (TAC) trough levels necessary to prevent rejection are established post heart/lung transplant (tx), there is little published literature on the proportion of…
  • 2016 American Transplant Congress

    Urine IP-10 as the Biomarker for ABMR in Kidney Transplant Recipient with DGF.

    N. Townamchai,1 A. Leelahavanichakul,2 J. Supapol,3 S. Wattanatorn,1 Y. Avihingsanon,1 K. Praditpornsilpa.1

    1Department of Medicine, Division of Nephrology, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand; 2Department of Microbiology, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand; 3Department of Surgery, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.

    Background: In the setting of DGF in kidney transplantation (KT), early acute ABMR, which needs early treatment, has to be differentiated from simple ischemic acute…
  • 2016 American Transplant Congress

    Pre-Transplant Anti-A Titers in Waitlisted A2 to B Kidney Transplant Candidates.

    D. Moore, I. Feurer, R. Forbes, A. DeMers, D. Shaffer.

    Vanderbilt University, Nashville, TN.

    Introduction:The KAS allocates A2 and A2B donor kidneys to blood type B candidates. Research is limited and variability exists among centers regarding the significance, relevance,…
  • 2016 American Transplant Congress

    Down-Regulated of Circulating miR-29b, miR-185 and NR_073415.2 in Post-Transplanted Patients with Cytomegalovirus Infection May Serve as Novel Biomarkers for Early Diagnosis.

    A. Yang, W. Ju, Z. Guo, C. Wu, J. Lin, M. Chen, R. Deng, E. Chen, Y. Gao, X. Zhu, X. He.

    Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Aims: Mortality of CMV infection in post-transplanted patients was quite high, which severely influencing the long-term survival of recipients. For giving them early treatment and…
  • 2016 American Transplant Congress

    CMV Monitoring Reduces Risk of Clinical Complications in Kidney Transplant Recipients.

    A. Gilbert, M. Cooper, J. Verbesey, R. Ghasemian, P. Abrams, J. Moore, M. Grafals, J. Chahine, S. Punnett, E. Hall, I. Anzak, B. Javaid.

    MedStar Georgetown Transplant Institute, Georgetown University School of Medicine, Washington, DC.

    Objective: Review the advantages of CMV viral load monitoring in preventing CMV associated complications in kidney transplant recipientsMethods: All individuals who underwent a kidney transplant…
  • 2016 American Transplant Congress

    Immune Tolerance Monitoring in Renal Allograft Tolerance Induced by Transient Mixed Chimerism in Nonhuman Primates and Humans.

    K. Hotta, T. Oura, K. Crisalli, D. Sachs, B. Cosim, T. Kawai.

    Center for Transplantation Science, Massachusetts General Hospital, Boston, MA.

    Background: Successful induction of allograft tolerance in MHC-mismatched kidney transplantation has been achieved after induction of transient chimerism in both nonhuman primates (NHP) and humans.…
  • 2016 American Transplant Congress

    Circulating miR-215, miR-let-7c miR-154, miR-193a, NR_036506.1 and NR_027669.1 as Biomarkers Predict Fungal Infection in Post-Transplanted Recipients.

    A. Yang, Z. Guo, W. Ju, C. Zhang, Z. Li, X. Yuan, Q. Zhao, H. Ye, Y. Liao, X. Zhu, X. He.

    Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Aims: The incidence of fungal infection in post-transplanted patients is 13%-17%, which seriously effecting perioperative survival and increasing their economic burden. We wanted to find…
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