ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Monitoring"

  • 2017 American Transplant Congress

    Rejection of Human Kidney Allografts According to BANFF Classification Is Associated with a Chemokine-Enriched Protein Microenvironment in Biopsy Tssue.

    C. Falk,1 K. Daemen,1 J. Keil,1 F. Lehner,2 H. Haller,3 J. Schmitz,4 J.-H. Bräsen,4 C. Blume.5

    1Institute of Transplant Immunology, IFB-Tx, Hannover Medical School, Hannover, Germany; 2Department of Abdominal, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany; 3Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany; 4Institute of Pathology, Hannover Medical School, Hannover, Germany; 5Institute for Technical Chemistry, Leibniz University, Hannover, Germany

    Background: Expression profiling efforts of biopsy tissue after kidney transplantation indicate that rejection can be defined by distinct signatures. Based on pathological evaluation (BANFF) as…
  • 2016 American Transplant Congress

    Detecting Renal Allograft Inflammation Using Quantitative Urine Metabolomics and CXCL10.

    J. Ho,1 A. Sharma,2 R. Mandal,3 D. Wishart,3 C. Wiebe,1 L. Storsley,1 M. Karpinski,1 I. Gibson,4 P. Nickerson,1 D. Rush.1

    1Internal Medicine, University of Manitoba, Winnipeg, MB, Canada; 2Pediatrics & Child Health, University of Manitoba, Winnipeg, MB, Canada; 3Biological Sciences, University of Alberta, Edmonton, AB, Canada; 4Pathology, University of Manitoba, Winnipeg, MB, Canada.

    Background. We studied urine metabolomics (UM) alone or combined with urine CXCL10 to non-invasively detect cellular infiltrates in renal allograft biopsies.Methods. Urines (n=137) were obtained…
  • 2016 American Transplant Congress

    Continuous Glucose Monitoring in the First 6 Weeks After Transplantation in Pancreas Transplant Recipients.

    K. Bonner,1 V. Dadlani,2 P. Thapa,2 M. Stegall,1 Y. Kudva.2

    1Department of Surgery, Division of Transplant Surgery, Mayo Clinic, Rochester; 2Department of Medicine, Division of Endocrinology, Mayo Clinic, Rochester.

    Introduction The maturation of Continuous glucose monitoring (CGM) technology enables accurate characterization of daily glucose control. We investigated glucose control using CGM in the first…
  • 2016 American Transplant Congress

    Vascular Composite Allotransplantation Collaborative Initiative Biobank: Bringing the Power Back to Research.

    J. Cheeseman, M.-B. Joshi, F. Leopardi, R. Osborne, D. Conlon, L. Stempora, M. Song, L. Cendales.

    Surgery, Duke University, Durham, NC.

    Refining Vascular Composite Allotransplantation (VCA) into a useful therapeutic option for patients in need of tissue reconstruction depends on the availability of biological specimens and…
  • 2016 American Transplant Congress

    Urinary Exosomal Annexin A1 Is a Predictive Biomarker of Post Kidney Transplant Complications.

    H. Harada,1 T. Murakami,2 C. Yamamoto,2 K. Hotta,1 N. Fukuzawa,1 M. Mitsuhashi.2

    1Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan; 2Hitachi Chemical Co. America, Ltd., Irvine, CA; 3Nanosomix, Inc., Aliso Viejo, CA.

    IntroductionMonitoring of kidney allograft condition is important. We had exhibited non-invasive diagnostic modality of post-kidney transplant complications using urine exosomal and microvesicule (EMV) mRNA of…
  • 2016 American Transplant Congress

    NanoString Detection of Gene Signatures in Urine During Acute Cellular Rejection of Kidney Grafts.

    K. Keslar,1 A. Zmijewska,2 J. Andriga,2 K. Newell,3 R. Mannon,2 P. Heeger,4 R. Fairchild.1

    1Cleveland Clinic, Cleveland; 2UAB, Birmingham; 3Emory, Atlanta; 4MSSM, New York.

    Considerable effort has focused on identification of gene expression patterns that may assist in diagnosis of acute cellular rejection. The NanoString platform offers a novel…
  • 2016 American Transplant Congress

    Impact of Ethnicity on Tacrolimus Trough/Dose Ratios Following Solid Organ Transplantation.

    A. Santeusanio, A. Owusu-Obeng, J. Jeff.

    Mount Sinai Hospital, New York.

    Objective: to assess tacrolimus dosing requirements based upon ethnicity in order to help guide future decisions regarding dosage initiation and titration among Hispanic and African…
  • 2016 American Transplant Congress

    Comparison of Actual versus Goal Tacrolimus Levels Post Cardiothoracic Transplant.

    E. Milas, I. Feurer, C. Truscott, J. Gray, N. Wilson, S. Bala, T. Dreher, M. Wigger, M. Steele, A. Shah, E. Lambright, D. Hanto.

    Vanderbilt Transplant Center, Nashville, TN.

    BackgroundAlthough target tacrolimus (TAC) trough levels necessary to prevent rejection are established post heart/lung transplant (tx), there is little published literature on the proportion of…
  • 2016 American Transplant Congress

    Urine IP-10 as the Biomarker for ABMR in Kidney Transplant Recipient with DGF.

    N. Townamchai,1 A. Leelahavanichakul,2 J. Supapol,3 S. Wattanatorn,1 Y. Avihingsanon,1 K. Praditpornsilpa.1

    1Department of Medicine, Division of Nephrology, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand; 2Department of Microbiology, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand; 3Department of Surgery, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.

    Background: In the setting of DGF in kidney transplantation (KT), early acute ABMR, which needs early treatment, has to be differentiated from simple ischemic acute…
  • 2016 American Transplant Congress

    Pre-Transplant Anti-A Titers in Waitlisted A2 to B Kidney Transplant Candidates.

    D. Moore, I. Feurer, R. Forbes, A. DeMers, D. Shaffer.

    Vanderbilt University, Nashville, TN.

    Introduction:The KAS allocates A2 and A2B donor kidneys to blood type B candidates. Research is limited and variability exists among centers regarding the significance, relevance,…
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