Articles tagged "Monitoring"

2018 American Transplant Congress
Follow-Up Care of Living Kidney Donors
N. Lam,¹ K. Lentine,² B. Hemmelgarn,³ S. Klarenbach,¹ R. Quinn,³ A. Lloyd,¹ S. Gourishankar,¹ A. Garg.⁴
¹University of Alberta, Edmonton, AB, Canada; ²Saint Louis University, St. Louis, MO; ³University of Calgary, Calgary, AB, Canada; ⁴Western University, London, ON, Canada.
The 2017 KDIGO guidelines recommend that living kidney donors receive lifelong annual follow-up care to assess renal health, including serum creatinine measurements with glomerular filtration…
2018 American Transplant Congress
CMV-Specific Cell-Mediated Immunity after Valgancyclovir Prophylaxis Predicts Late Onset CMV Infection in Kidney Transplant Patients
M. Jarque,¹ E. Crespo,¹ E. Melilli,² A. Manonelles,² N. Montero,² S. Luque,¹ J. Cruzado,^1,2 J. Grinyo,^1,2 O. Bestard.^1,2
¹Experimental Nephrology Laboratory, IDIBELL, Barcelona, Spain; ²Nephrology Department, Bellvitge University Hospital, Barcelona, Spain.
Background: There is currently no means to predict late-onset CMV infection after a long course of post-transplant Valgancyclovir prophylaxis therapy and its development still negatively…
2018 American Transplant Congress
Validation of the PROMIS-57 and PROMIS-29 Questionnaires in Kidney Transplant Recipients
E. Tang, A. Bansal, S. Cao, M. Li, M. Novak, I. Mucsi.
University Health Network, Toronto, Canada.
Background: The Patient Reported Outcomes Measurement Information System (PROMIS) provides generalizable and universal measures of various domains of patient reported outcomes. The PROMIS-57 and PROMIS-29…
2018 American Transplant Congress
Incidence of Epstein Barr Virus (EBV) DNAemia in EBV-Seronegative Solid Organ Transplant (SOT) Recipients with EBV-Seropositive Donors
C. Burton,¹ C. Mabilangan,² J. Preiksaitis.²
¹Pediatrics, University of Alberta, Edmonton, Canada; ²Medicine, University of Alberta, Edmonton, Canada.
Purpose: Since 2002, a pre-emptive approach to post-transplant lymhoproliferative disease prevention has been used at our center that includes EBV viral load (VL) monitoring in…
2018 American Transplant Congress
Benefit of Patient Portal Usage in Non-High Risk Kidney Transplant Recipients
A. Osband, J. Machan, P. Morrissey.
Surgery, Alpert Medical School of Brown University, Providence, RI.
Background: With widespread adoption of EHR (electronic health record), patients have access to a patient portal where they can view and thereby help monitor their…
2018 American Transplant Congress
Non-Invasive Diagnostic of Renal Allograft Rejection via Urine Metabolites Using NMR-Spectroscopy
M. Banas,¹ S. Neumann,² P. Pagel,² D. Chittka,¹ V. Pfahlert,² B. Banas.¹
¹Department of Nephrology, University Hospital Regensburg, Regensburg, Germany; ²numares HEALTH, Regensburg, Germany.
Introduction and BackgroundPost-transplant surveillance for acute rejection is typically based on regular monitoring of serum creatinine levels and consecutive biopsies upon functional renal impairment. Attempts…
2018 American Transplant Congress
High Grade Cytomegalovirus Viremia Events in Solid Organ Transplant Recipients: Description and Quality Improvement
M. Spinner,¹ V. Athans,¹ C. Koval.²
¹Dept. of Pharmacy, Cleveland Clinic, Cleveland, OH; ²Dept. of Infectious Diseases, Cleveland Clinic, Cleveland, OH.
Background: High grade cytomegalovirus viremia (HGCMVV) often results in symptomatic disease requiring IV antiviral therapy and is associated with CMV recurrence and resistance. We postulated…
2018 American Transplant Congress
Unique Gene Expression Signatures in Urine Distinguish BK Virus Nephropathy from Acute Rejection in Kidney Transplant Patients with Graft Dysfunction
K. Keslar,¹ P. Gotwald,¹ W. Xu,² A. Zmijewska,³ J. Chen,³ K. Newell,⁴ P. Heeger,⁵ J. Bromberg,⁶ R. Mannon,³ R. Fairchild,¹ The CTOT Consortium.
¹Cleveland Clinic, Cleveland, OH; ²Nanostring Technologies, Seattle, WA; ³University of Alabama at Birmingham, Birmingham, AL; ⁴Emory University, Atlanta, GA; ⁵Icahn School of Medicine at Mt. Sinai, New York, NY; ⁶University of Maryland, Baltimore, MD.
Acute cellular rejection and BK virus nephropathy both cause deteriorating graft function that can lead to graft loss. Distinguishing the two conditions rapidly and accurately…
2018 American Transplant Congress
Evaluation and Cost Burden of Inappropriately Drawn Immunosuppression Trough Levels in the Acute Care Setting at an Academic Medical Center
A. Brown, J. Geyston, A. Agarwal, B. Jones, W. Ally.
University of Virginia Health System, Charlottesville, VA.
Trough drug levels in narrow therapeutic index medications, such as CNI and mTOR inhibitors are used to estimate total drug exposure. Inappropriately measured trough levels…
2018 American Transplant Congress
Origin and Pattern of Human Polyomaviruses Replication after Kidney Transplantation: A Prospective Study
E. Favi,¹ S. Delbue,² C. Colico,¹ P. Ferrante,² S. Villani,² I. Perna,² N. Mondoni,² A. Giussani,¹ L. Clementoni,¹ P. Messa,³ M. Ferraresso.¹
¹Kidney Transplantation, Fondazione IRCCS Ca' Granda, Milan, Italy; ²Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy; ³Nephrology, Fondazione IRCCS Ca' Granda, Milan, Italy.
Background. Human Polyomaviruses (HPyVs) are able to establish latent infection in the kidney of the host. Immunosuppression is recognized risk factor for HPyVs reactivation. Besides…