2018 American Transplant Congress
Four Eyes Are Better Than Two: Improving Laboratory Report Quality Control
1Quality Assurance, LABS, Inc., Centennial, CO; 2Infectious Disease, LABS, Inc., Philadelphia, PA.
Background: Our STAT donor-screening lab implemented a new LIMS that is used to manage patient orders, testing and reporting. We intentionally customized the LIMS to…2018 American Transplant Congress
T Cell Immunomonitoring Including Donor Specific Treg Expansion Prospectively Predicts Renal Allograft Tolerance Induced by Transient Mixed Chimerism
Center for Transplant Science, Massachusetts General Hospital, Boston, MA.
Background: Successful induction of allograft tolerance in MHC-mismatched kidney transplantation has been achieved after induction of transient chimerism in both nonhuman primates (NHP) and humans.…2018 American Transplant Congress
Follow-Up Care of Living Kidney Donors
The 2017 KDIGO guidelines recommend that living kidney donors receive lifelong annual follow-up care to assess renal health, including serum creatinine measurements with glomerular filtration…2018 American Transplant Congress
CMV-Specific Cell-Mediated Immunity after Valgancyclovir Prophylaxis Predicts Late Onset CMV Infection in Kidney Transplant Patients
Background: There is currently no means to predict late-onset CMV infection after a long course of post-transplant Valgancyclovir prophylaxis therapy and its development still negatively…2018 American Transplant Congress
Validation of the PROMIS-57 and PROMIS-29 Questionnaires in Kidney Transplant Recipients
University Health Network, Toronto, Canada.
Background: The Patient Reported Outcomes Measurement Information System (PROMIS) provides generalizable and universal measures of various domains of patient reported outcomes. The PROMIS-57 and PROMIS-29…2018 American Transplant Congress
Incidence of Epstein Barr Virus (EBV) DNAemia in EBV-Seronegative Solid Organ Transplant (SOT) Recipients with EBV-Seropositive Donors
Purpose: Since 2002, a pre-emptive approach to post-transplant lymhoproliferative disease prevention has been used at our center that includes EBV viral load (VL) monitoring in…2018 American Transplant Congress
Benefit of Patient Portal Usage in Non-High Risk Kidney Transplant Recipients
Surgery, Alpert Medical School of Brown University, Providence, RI.
Background: With widespread adoption of EHR (electronic health record), patients have access to a patient portal where they can view and thereby help monitor their…2018 American Transplant Congress
Non-Invasive Diagnostic of Renal Allograft Rejection via Urine Metabolites Using NMR-Spectroscopy
Introduction and BackgroundPost-transplant surveillance for acute rejection is typically based on regular monitoring of serum creatinine levels and consecutive biopsies upon functional renal impairment. Attempts…2018 American Transplant Congress
High Grade Cytomegalovirus Viremia Events in Solid Organ Transplant Recipients: Description and Quality Improvement
Background: High grade cytomegalovirus viremia (HGCMVV) often results in symptomatic disease requiring IV antiviral therapy and is associated with CMV recurrence and resistance. We postulated…2018 American Transplant Congress
Unique Gene Expression Signatures in Urine Distinguish BK Virus Nephropathy from Acute Rejection in Kidney Transplant Patients with Graft Dysfunction
Acute cellular rejection and BK virus nephropathy both cause deteriorating graft function that can lead to graft loss. Distinguishing the two conditions rapidly and accurately…
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