2019 American Transplant Congress
Matrix Metalloproteinase-9 and Neutrophil Extracellular Traps in Human and Mouse Liver Ischemia and Reperfusion Injury
Dumont-UCLA Transplant Center, Los Angeles, CA
*Purpose: Neutrophils are key mediators of ischemia/reperfusion injury (IRI) in orthotopic liver transplantation (OLT). Once activated, they release nuclear DNA web-like structures called neutrophil extracellular…2018 American Transplant Congress
Double Deficiency of Gelatinase-A and Gelatinase-B Does Not Protect against Hepatic Ischemia Reperfusion Injury
Dumont-UCLA Transplant Center, Los Angeles.
Gelatinases, consisting of gelatinase A (MMP-2; 72 KDa) and gelatinase B (MMP-9; 92KDa), are a subgroup of matrix metalloproteinases (MMPs) with key roles in a…2016 American Transplant Congress
Matrix Metalloproteinase-9 in Human Orthotopic Liver Transplant Biopsies.
The Dumont-UCLA Transplant Center, Los Angeles.
Liver ischemia reperfusion injury (IRI) is an inflammatory event that contributes to graft dysfunction in orthotopic liver transplantation (OLT). Matrix Metalloproteinases (MMPs) are responsible for…2016 American Transplant Congress
Anti-Inflammatory Effects of AAV-Mediated TIMP-1 Gene Transfer in Hepatic Ischemia-Reperfusion Injury.
The Dumont-UCLA Transplant Center, Los Angeles.
Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase1 (TIMP-1) is the…2016 American Transplant Congress
Matrix Metalloproteinase-2 (MMP-2) Activity Protects Against Hepatic Ischemia Reperfusion Injury Through MMP-9-Dependent and MMP-9-Independent Mechanisms.
The Dumont-UCLA Transplant Center, Los Angeles.
Matrix Metalloproteinases (MMPs) are a family of proteinases with key roles in tissue homeostasis, inflammation and repair. We have recently shown that MMP-9 and MMP-2,…2015 American Transplant Congress
AAV-Mediated TIMP-1 Gene Therapy Ameliorates Hepatic Ischemia/Reperfusion Injury
The Dumont-UCLA Transplant Center, Los Angeles.
Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase-1 (TIMP-1) is the…
American Transplant Congress abstracts