ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Metabolic complications"

  • 2016 American Transplant Congress

    Pre-Transplant Bariatric Surgery and One-Year Graft Loss Risk in Kidney Transplants.

    G. Mour, J. Zhang, Z. Su, D. Taber, P. Mauldin, T. Srinivas.

    MUSC, Charleston.

    Background: Several centers recommend bariatric surgery (BS) pre-transplantation (pre-Tx) with arbitrary BMI cutoffs. The effects of BS on Tx outcome are unclear. We studied the…
  • 2015 American Transplant Congress

    Bladder Drainage of Pancreas Transplants Alone: Friend or Foe?

    M. Bellini,1 G. Spoletini,2 S. Reddy,1 J. Gilbert,1 I. Quiroga,1 R. Ploeg,1 E. Sharples,3 S. Sinha,1 A. Vaidya,1 P. Friend.1

    1Nuffield Department of Surgery, Oxford University Hospital NHS Trust, Oxford, United Kingdom; 2Department of Hepatobiliary and Transplant Surgery, Royal Free London NHS Trust, London, United Kingdom; 3Nuffield Department of Medicine, Oxford University Hospital NHS Trust, Oxford, United Kingdom.

    Introduction: Immunological monitoring of Pancreas Transplants Alone (PTA) remains a challenge and bladder drainage is thought to facilitate early detection of rejection but may lead…
  • 2015 American Transplant Congress

    Excessive Weight Gain After Pancreas Transplant: Transitioning from Type 1 to Type 2 Diabetes?

    A. Islam,1 A. Lawless,1 L. Teeter,3 E. Graviss,3 D. Victor,4 A. Sadhu,4 S. Patel,6 A. Gaber,1 R. Knight.1

    1Department of Surgery, Houston Methodist Hospital, Houston, TX; 2Department of Pathology & Genomic Medicine, Houston Methodist Hospital, Houston, TX; 3Department of Medicine, Houston Methodist Hospital, Houston, TX; 4Department of Pharmacy, Houston Methodist Hospital, Houston, TX.

    AIM:Excessive weight gain (EWG) after pancreas transplantation may increase the risk of post-transplant diabetes mellitus and metabolic syndrome. This study aimed to define the incidence,…
  • 2015 American Transplant Congress

    Effect of Living Kidney Donation on Glucose Metabolism and Insulin Resistance

    B. Tanriover,1 P. Mohan,2 S. Cremers,3 I. Lingvay.4

    1Medicine/Nephrology, UT Southwestern, Dallas, TX; 2Medicine/Nephrology, Medical University of South Carolina, Charleston, SC; 3Biomarkers Core Laboratory, Columbia University, New York, NY; 4Medicine/Endocrinology, UT Southwestern, Dallas, TX.

    The kidney contributes to glucose hemostasis through processes of insulin metabolism, gluconeogenesis, and glucose filtration. Little is known on insulin sensitivity in living kidney donors…
  • 2015 American Transplant Congress

    Serum Osteoprotegerin Levels Positively Correlate With Peripheral Arterial Stiffness in Kidney Transplantation Patients

    M.-C. Lee,1,2 G.-J. Ho,1 Y.-C. Chen,1 B.-G. Hsu.2

    1Department of Surgery, Tzu Chi General Hospital, Hualien, Taiwan; 2Department of Medicine, School of Medicine Tzu Chi University, Hualien, Taiwan; 3Department of Medicine, Tzu Chi General Hospital, Hualien, Taiwan.

    Objective: Recent studies found osteoprotegerin (OPG) is associated with increased pulse wave velocity and may reflect endothelial dysfunction. The aim of this study was to…
  • 2015 American Transplant Congress

    Investigation of Myocardial Function in Pediatric Transplant Recipients

    K. Sgambat, S. Clauss, M. Lasota, A. Moudgil.

    Children's National, Washington, DC.

    Purpose: In light of the major impact of cardiovascular morbidity on long-term transplant outcomes, a prospective controlled study was conducted to investigate changes in myocardial…
  • 2015 American Transplant Congress

    Diabetes Exacerbates Liver Ischemia and Reperfusion Injury By Activating the AGE-RAGE Pathway in Kupffer Cells

    S. Yue, J. Zhu, J. Rao, J. Kupiec-Weglinski, R. Busuttil, Y. Zhai.

    Surgery, UCLA, Los Angeles, CA.

    Although pre-transplant diabetes has been documented as a risk factor for mortality post-liver transplant, the underlying mechanism remains obscure. In a murine liver partial warm…
  • 2015 American Transplant Congress

    A Prospective and Randomized Study of Conversion from Tacrolimus to Cyclosporine A to Improve Glucose Metabolism in Patients With New-Onset Diabetes Mellitus After Renal Transplantation

    K. Wissing,1 D. Abramowicz,2 L. Weekers,3 K. Budde,4 T. Rath,5 O. Witzke,6 D. Kuypers.7

    1Universitair Ziekenhuis Brussel, Brussels, Belgium; 2Universitair Ziekenhuis Antwerpen, Antwerpen, Belgium; 3Centre Hospitalier Universitaire Liège, Liège, Belgium; 4Charité Universitätsmedizin Berlin, Berlin, Germany; 5Westpfalz Klinikum Kaiserslautern, Kaiserslautern, Germany; 6Universitätsklinikum Essen, Essen, Germany; 7Universitair Ziekenhuis Leuven, Leuven, Belgium.

    Background: The present prospective and randomized study was designed to assess whether conversion from tacrolimus (Tac) to cyclosporine A (CsA) can reverse posttransplantation diabetes mellitus…
  • 2015 American Transplant Congress

    Bariatric Surgery Prolongs Allograft Survival by Promoting Th2 Conditions

    M. Quante, A. ElKhal, H. Rodriguez, R. Abdi, F. Krenzien, H. Uehara, S. Tullius.

    Division of Transplant Surgery and Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston.

    Background: Obesity is linked to chronic low-grade inflammation. We hypothesized that I) obesity will accelerate allograft rejection linked to pro-inflammatory immune responses and that II)…
  • 2015 American Transplant Congress

    Longitudinal Assessment of Endothelial Function Following Kidney Transplantation

    C. Kensinger,1 G. Chen,2 A. Bian,2 T. Ikizler,3 K. Birdwell.3

    1Department of General Surgery, Vanderbilt University Medical Center, Nashville, TN; 2Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN; 3Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN.

    Purpose:Evaluate the progression of endothelial function as a marker of cardiovascular disease following kidney transplant.Background:Endothelial dysfunction is associated with cardiovascular disease (CVD) in end stage…
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