Articles tagged "marginal"

2018 American Transplant Congress
Donor Acute Kidney Injury Does Not Affect Fibrosis on 1 Year Post-Transplant Kidney Biopsy
D. van der Windt, X. Chen, K. Lemon, C. Wu, N. Shah, R. Mehta, C. Puttarajappa, P. Sood, S. Hariharan, A. Ganoza, M. Wijkstrom, A. Humar, A. Tevar.
Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA.
PurposeThe use of kidneys from deceased donors with acute kidney injury (AKI) at the time of donation is a potential method by which to expand…
2018 American Transplant Congress
Outcomes of DCD Renal Transplantation from Donors with Acute Kidney Injury
E. Grodstein, J. Yang, V. Nair, L. Teperman.
Northwell Health, Manhasset, NY.
BackgroundDeceased donor kidneys with acute kidney injury (AKI) are a viable source of organs, yet are frequently discarded. Outcomes of deceased donor renal transplantation (DDRT)…
2018 American Transplant Congress
Temporal Trends, Predictive Factors, and Regional Differences in Discard of Increased-Risk Kidneys
J. Lipinska, D. Clark, J. Whiting.
Surgery, Maine Medical Center, Portland, ME.
Purpose: Public Health Service (PHS) criteria designate certain deceased donors (DD) as entailing increased risk (IR) for disease transmission, and these constitute an expanding proportion…
2018 American Transplant Congress
Short-Term Outcome Prediction Model in Deceased Donor Kidney Transplant Recipients
K. Archer,¹ Y. Zhang,¹ S. Bontha,² E. Akalin,³ L. Gallon,⁴ D. Maluf,² V. Mas.²
¹OSU, Columbus; ²UVA, Charlottesville; ³Montefiore, New York; ⁴NWU, Chicago.
Background: Lack of accurate outcome prediction models may be a reason for the increase in organ discard rate that further burdens the growing kidney transplant…
2018 American Transplant Congress
Factors Predicting Viability Achievement on Discarded Donor Livers Submitted to Extra-Corporeal Machine Perfusion
Y. Boteon,^1,2 R. Laing,^1,2 A. Schlegel,² J. Attard,^1,2 L. Wallace,¹ A. Smith,² T. Perera,² J. Isaac,² D. Mirza,² S. Afford,¹ H. Mergental.²
¹National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; ²Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.
Background: Ex-vivo machine perfusion of livers (MP) may offer superior preservation for marginal donor organs. During normothermic machine perfusion (NMP) is possible to assess liver…
2018 American Transplant Congress
Elevated Donor Terminal Creatinine Does Not Appear to Be Associated with Worse Outcomes in Kidney Transplantation
S. Rayhill, J. Haldorson.
U Washington, Seattly.
There is justified reluctance to use kidneys from donors with significantly elevated creatinine as they may have severe, irreversible injury. Recently, thanks, in part to…
2018 American Transplant Congress
Influence of Liver Allograft Steatosis on Postoperative Acute Kidney Injury
C. Jadlowiec,¹ S. Mao,² D. Abdelwahab,¹ A. Nehra,² T. Taner.²
¹Mayo Clinic, Phoenix, AZ; ²Mayo Clinic, Rochester, MN.
With the ongoing organ shortage, there has been an increased interest in using moderately steatotic liver allografts. The impact of such allografts on recipients' post-liver…
2018 American Transplant Congress
Extended Criteria Donors Have Higher Expression of Inflammatory Genes Than Standard Donors
M. Abbud-Filho,^1,2,3 M. Fernandes-Charpiot,^1,2 M. Baptista,^1,2 H. Caldas,^1,2 G. Florim.¹
¹Medicine, Laboratory of Immunology and Experimental Transplantation - LITEX, Medical School of Sao Jose do Rio Preto, Sao Jose do Rio Preto, Sao Paulo, Brazil; ²Transplant, Kidney Transplant Unit, Hospital de Base, FAMERP/FUNFARME, Sao Jose do Rio Preto, Sao Paulo, Brazil; ³Urology and Nephrology Institute, Sao Jose do Rio Preto, Sao Paulo, Brazil.
Background.Changes to an organ occur at the time of brain death where a series of inflammatory modify occur within the organ. Because it is not…
2018 American Transplant Congress
Kidney Transplantation in Older Recipients: Preemptive High KDPI Kidney vs. Lower KDPI Kidney after Varying Dialysis Vintage
B. Chopra, S. Hussain, K. Sureshkumar.
Nephrology and Hypertension, Allegheny General Hospital, Pittsburgh, PA.
Dialysis vintage is an independent predictor of adverse long-term kidney transplant outcomes. Transplantation of "marginal" kidneys also results in inferior outcomes. We sought to analyze…
2018 American Transplant Congress
Viability Outcomes for Donor Livers Discarded Due to Steatosis Following Extra-Corporeal Machine Perfusion of the Liver
Y. Boteon,^1,2 R. Laing,^1,2 D. Neil,² A. Schlegel,² J. Attard,^1,2 G. Reynold,¹ P. Muiesan,² D. Mirza,² S. Afford,¹ H. Mergental.²
¹National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; ²Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.
Background: Steatosis is the main reason for discarding donor livers worldwide. Ex-vivo machine perfusion offers superior preservation for marginal organs and permits viability testing during…