Articles tagged "marginal"

2015 American Transplant Congress
Moderate KDPI (35-85) and High KDPI (>85) Grafts Yield Similar Graft Function and Survival
A. Gupta,² G. Francos,² C. Gorn,³ A. Shah.¹
¹Surgery, Thomas Jefferson University, Philadelphia, PA; ²Nephrology, Thomas Jefferson University, Philadelphia, PA; ³Transplantation, Thomas Jefferson University, Philadelphia, PA.
Purpose – To study the impact of donor KDPI on post-transplant kidney function and survival.Methods – We reviewed the records of 309 deceased donor kidney…
2015 American Transplant Congress
Fibrosis, Not Quantitative NGAL-Staining, in Day-10 Protocol Biopsies Predicts Prolonged Duration of Functional Delayed Graft Function in a Cohort of DCD Kidney Transplant Recipients
J. Bank,¹ M. Reinders,¹ M. Mallat,¹ N. Schlagwein,¹ S. van der Kooij,¹ D. van Gijlswijk,¹ I. Bajema,² C. van Kooten,¹ H. de Fijter.¹
¹Nephrology, LUMC, Leiden, Netherlands; ²Pathology, LUMC, Leiden, Netherlands.
Introduction: Extended criteria deceased kidneys are associated with prolonged delayed graft function and worse patient survival. Therefore it is important to identify factors in marginal…
2015 American Transplant Congress
Protecting Older Patients from Dialysis: The Survival Benefit of Preemptive Transplant With High KDPI Allografts
C. Jay,¹ K. Washburn,¹ P. Dean,² R. Helmick,² M. Stegall.²
¹Transplant Center, University of Texas Health Science Center, San Antonio, TX; ²Department of Surgery, Division of Transplantation, Mayo Clinic, Rochester, MN.
BACKGROUND: Mortality on dialysis remain markedly elevated in patients over 60 years old. Preemptive kidney transplantation (PreKT) represents a means of avoiding the risks of…
2015 American Transplant Congress
Hypothermic Machine Perfusion Improves the Quality of Marginal Donor Pancreata
M. Leemkuil,¹ M. Engelse,² R. Ploeg,³ E. de Koning,² C. Krikke,¹ H. Leuvenink.¹
¹Surgery, University Medical Center Groningen, Groningen, Netherlands; ²Nephrology, Leiden University Medical Center, Leiden, Netherlands; ³Transplant Biology, Oxford Transplant Center, Oxford, United Kingdom.
Introduction. Pancreas or islet transplantation is considered the most effective treatment for patients with type 1 diabetes mellitus. Due to the persistent organ shortage, pancreata…
2015 American Transplant Congress
Parameters of Machine Perfusion Evaluating Quality of Kidneys from DCD/ECD Donors
G. Chen, C. Wang, J. Qiu, M. Han, X. He, L. Chen.
Organ Transplant Center, The first affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Background Donors from donation after cardiac death(DCD) and expanded criteria donors(ECD) have poorer outcomes compared to standard deceased donors(SCD). It is important to evaluate quality…
2015 American Transplant Congress
No Tumor Recurrence After Renal Cell Carcinoma Resected Kidney Transplantation – 5 Year Follow Up
M. Zwierzchoniewska,¹ K. Fong,¹ D. Patel,¹ L. Mou, W. Lim,² B. He,¹ L. Delriviere.¹
¹Western Australian Kidney Transplant Surgery Service, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia; ²Western Australian Kidney Transplant Service, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
INTRODUCTION:Organ shortage remains the single most significant impediment to increasing low rate of kidney transplantation. One of the strategies to improve it, is a utilisation…
2015 American Transplant Congress
Preemptive Deceased Donor Transplant With Kidney Donor Profile Index Scores Greater Than 85 Not Associated With a Survival Benefit
D. Keith, A. Nishio Lucar, G. Vranic.
University of Virginia, Charlottesville, VA.
Preemptively listed candidates for kidney transplant are a unique patient population with regard to marginal quality kidney acceptance as they are not yet dialysis dependent.…
2015 American Transplant Congress
Delivery of Heme Oxygenase-1-Cell Penetrating Peptide (HO-1-CPP) Into Hepatocytes, Kupffer and Islet Cells in In Vitro and Ex Vivo Models of Cold Ischemia
A. Venkatachalam,¹ C. Wood,¹ Q. Hu,¹ I. Alwayn.²
¹Surgery, Dalhousie University, Halifax, NS, Canada; ²Surgery, Pathology, Microbiology & Immunology, Surgical Lead Multi Organ Transplant Program, QEII Health Sciences Center, Dalhousie University, Halifax, NS, Canada.
In an attempt to increase the number of donor organs available to transplantation extended criteria donor (ECD) organs are more frequently considered. Unfortunately, ECD organs…
2015 American Transplant Congress
Come Again? Part 2, Exploring Causes for Increased Rehospitalization in ECD Kidney Recipients
C. Dunn, M. Hung, S. Greenstein.
Surgery, Albert Einstein College of Medicine, Bronx, NY.
Previously, we demonstrated that ECD kidney recipients had an increased rate of re-hospitalization within 1 year but not 2 years post-transplant . This was a…
2015 American Transplant Congress
Effect of Distinct Immunosuppressive Protocols On the Profile of Cytokines Expression in Renal Transplant Recipients of Extended Criteria Donor Kidneys
C. Montoro Mazeti,¹ C. Zangrossi Dezotti,¹ I. Fernandes-Charpiot,^1,2 H. Caldas,¹ M. Baptista,^1,2 M. Abbud Filho.^1,2,3
¹Laboratory of Immunology and Experimental Transplantation, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto, SP, Brazil; ²Department of Medicine, Division of Nephrology, Sao Jose do Rio Preto Medical School, Sao Jose do Rio Preto, SP, Brazil; ³Urology and Nephrology Institute, Urology and Nephrology Institute, Sao Jose do Rio Preto, SP, Brazil.
Background: Transplant recipients (RTx) of kidneys classified as extended criteria (ECD) seems to have worst outcomes when compared with RTx of standard kidneys (SCD) and…