Articles tagged "marginal"

2016 American Transplant Congress
Replacing Cold Storage with Normothermic Ex Vivo Kidney Perfusion Improves Function of Grafts Retrieved After Circulatory Death (DCD).
J. Kaths,^1,2 Y.-M. Chun,¹ D. Cen,¹ J. Echeverri,¹ I. Linares,¹ P. Yip,³ R. John,³ D. Bagli,⁴ I. Mucsi,⁵ A. Ghanekar,¹ D. Grant,¹ L. Robinson,² M. Selzner.¹
¹Department of Surgery, Multi Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada; ²Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada; ³Laboratory Medicine & Pathobiology, Toronto General Hospital, Toronto, ON, Canada; ⁴Departments of Surgery (Urology) & Physiology, The Hospital for Sick Children, Toronto, ON, Canada; ⁵Department of Medicine, Multi Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
Normothermic ex vivo kidney perfusion (NEVKP) and avoidance of static cold storage (SCS) is an attractive strategy to minimize injury of DCD kidney grafts. We…
2016 American Transplant Congress
Pancreas Transplantation from Pediatric Donors: A UNOS Registry Analysis.
M. Spaggiari, I. Tzvetanov, H. Jeon, E. Benedetti, J. Oberholzer.
Division of Transplantation, University of Illinois at Chicago, Chicago.
Introduction: Major concerns about the utilization of pediatric pancreata are the cumulative islet mass and the increased technical complexity. The primary aim of this study…
2016 American Transplant Congress
Utilization and Discard of HCV+ Donor Livers in the Advent of Direct-Acting Antiviral Therapy.
M. Bowring, L. Kucirka, A. Massie, X. Luo, M. Sulkowski, D. Segev, C. Durand.
JHU, Baltimore.
While 45% of liver candidates are hepatitis C (HCV)-antibody positive (+) and might benefit from a HCV+ donor liver, only a small proportion receive one.…
2016 American Transplant Congress
Original KDRI Predicts Kidney Graft Failure in a Brazilian Cohort.
J. Reusing Jr.,¹ C. Nihei,¹ A. Lino de Souza,² E. David-Neto,¹ C. Ventura.³
¹Kidney Transplant Unit, Hospital das Clínicas, University of São Paulo School of Medicine, São Paulo, SP, Brazil; ²Psychobiology Department, Universidade Federal de São Paulo, São Paulo, SP, Brazil; ³Renal Transplant Unit, Hospital das Clinicas of the University of Sao Paulo Medical School, São Paulo, SP, Brazil.
Current US allocation system for kidney transplantation (KT) is based on KDRI (Kidney Donor Risk Index). In Brazil, it is still based on HLA-compatibility; donor…
2016 American Transplant Congress
Kidney Transplantation from Thin Basement Membrane Nephropathy Donor.
C. Choi,¹ A. Han,¹ S.-Y. Kim,¹ S. Cho,¹ M.-J. Cho,¹ C. Lee,¹ S. Ahn,¹ S.-K. Min,¹ J. Ha,¹ M. Park,² S. Kim,³ I. Jung,¹ S.-I. Min.¹
¹Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea; ²Laboratory Medicine, Korea Organ Donation Agency, Seoul, Republic of Korea; ³Surgery, Myongji Hospital, Goyang, Gyeonggi-do, Republic of Korea.
PurposeThin basement membrane nephropathy (TBMN) is the most common cause of persistent glomerular hematuria. Most individuals with TBMN shows benign course, but it is hard…
2016 American Transplant Congress
Abrogating Donor-Derived Myd88 Signaling Impairs the Recruitment of Recipient Neutrophils and CD8 T Cells into Lung Allografts in Mice.
Z. Zheng,¹ J.-J. Wang,¹ X. Yeap,¹ X. Kang,¹ Y. Xie,¹ X. Luo,² Z. Zhang.¹
¹Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL; ²Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.
Objectives: Transplant ischemia reperfusion injury (IRI) mediated primary graft dysfunction (PGD) remains the predominant cause of short- and long-term graft loss in lung transplantation. This…
2016 American Transplant Congress
The Impact of Early Acute Rejection and Delayed Graft Function on Graft Outcomes at Six Months in Adult Deceased Donor Kidney Recipients.
D. Keith, G. Vranic, A. Nishio Lucar.
University of Virginia, Charlottesville, VA.
Graft function as determined by GFR is an important predictor of long-term graft and patient survival after deceased donor kidney transplantation. KDPI is an important…
2016 American Transplant Congress
The UK Kidney Donor Risk Index Score Predicts the Development of TRAS Post Deceased Donor Transplantation.
M. Willicombe, A. Baheerathan, S. Moser, A. McLean, M. Hammady, W. Gedroyc, D. Taube.
Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
Introduction: Transplant renal artery stenosis (TRAS) is a heterogeneous disorder with different subtypes and aetiologies, which include traditional cardiovascular and transplant specific risk factors. Whether…
2016 American Transplant Congress
Ex-Vivo Normothermic Perfusion for Assessment of High Risk Deceased Donor Kidneys for Transplantation.
S. Kabagambe, I. Palma, Y. Smolin, T. Boyer, I. Palma, J. Sageshima, C. Santhanakrishnan, C. Troppmann, J. McVicar, R. Perez.
Surgery, University of California-Davis, Sacramento, CA.
Despite the organ shortage, many procured deceased donor kidneys are deemed too high risk for failure and discarded. Ex-vivo normothermic perfusion (EVNP) may be useful…
2016 American Transplant Congress
A Risk Quantification Score for Heart Transplants: A Heart Donor Risk Index.
A. Israni,^1,2 D. Zaun,¹ J. Snyder,¹ N. Salkowski,¹ H. Xiong,¹ B. Kasiske,^1,2 M. Colvin,^1,3 M. Colvin.^1,3
¹Scientific Registry of Transplant Recipients, Minneapolis; ²Hennepin County Medical Center, Univ of MN, Minneapolis; ³Univ of Michigan, Ann Arbor.
Background: To better risk stratify heart transplants, we developed a continuous heart donor risk index (HDRI) based on heart donors to quantify heart allograft failure.Methods:…