Articles tagged "marginal"

2016 American Transplant Congress
Analysis of Local versus Imported Expanded Criteria Donor (ECD) Kidneys: A Single Center Experience with 497 ECD Kidney Transplants.
M. Khan,¹ H. El-Hennawy,¹ A. Farney,¹ J. Rogers,¹ G. Orlando,¹ A. Reeves-Daniel,² A. Palanisamy,² M. Gautreaux,³ S. Iskandar,³ W. Doares,⁴ S. Kaczmorski,⁴ R. Stratta.¹
¹Surgery, Wake Forest, Winston-Salem, NC; ²Internal Medicine, Wake Forest, Winston-Salem, NC; ³Pathology, Wake Forest, Winston-Salem, NC; ⁴Pharmacy, Wake Forest, Winston-Salem, NC.
With the new Kidney Allocation System, broader sharing of expanded criteria donor (ECD) kidneys may occur, which may influence discard rates and survival outcomes. To…
2016 American Transplant Congress
Pediatric En Bloc Kidney Transplants Reduce DGF and Are Misrepresented by the KDPI.
M. Khan,¹ H. El-Hennawy,¹ A. Farney,¹ J. Rogers,¹ G. Orlando,¹ A. Reeves-Daniel,² A. Palanisamy,² M. Gautreaux,³ S. Iskandar,³ W. Doares,⁴ S. Kaczmorski,⁴ R. Stratta.¹
¹Surgery, Wake Forest, Winston-Salem, NC; ²Internal Medicine, Wake Forest, Winston-Salem, NC; ³Pathology, Wake Forest, Winston-Salem, NC; ⁴Pharmacy, Wake Forest, Winston-Salem, NC.
Controversy exists regarding optimal use of kidneys from small pediatric donors (SPDs). The study purpose was to compare outcomes between single and dual en bloc…
2016 American Transplant Congress
Fractional Excretion of NGAL Instead of ^99mTcMAG₃Renography to Monitor Resolution of Delayed Graft Function.
J. Bank, M. Reinders, L. Noordermeer, M. Mallat, S. van der Kooij, C. van Kooten, J. de Fijter.
Nephrology, Leiden University Medical Center, Leiden, Netherlands.
Introduction: Kidneys transplanted from extended criteria donors have a higher prevalence of delayed graft function (DGF). Early identification of factors that prolong duration of DGF…
2016 American Transplant Congress
Serelaxin Decreases the Severity of Cold Ischemia-Reperfusion Injury After Liver Transplantation in Mice.
S. Kageyama, K. Nakamura, R. Busuttil, J. Kupiec-Weglinski.
The Dumont-UCLA Transplantation Center, UCLA, Los Angeles, CA.
Background. Extended cold preservation contributes to ischemia-reperfusion injury (IRI), which impairs graft function and leads to poor clinical outcomes. Serelaxin (SER), a recombinant form of…
2016 American Transplant Congress
High KDPI Kidneys (>85%) Do Not Adversely Affect HRQOL After Kidney Transplantation.
R. Forbes, I. Feurer, D. LaNeve, C. Gamble, D. Shaffer.
Vanderbilt University Medical Center, Nashville, TN.
Background. Since December 2014, deceased donor kidneys are allocated based on a kidney donor profile index (KDPI) by four sequences, A thru D. Estimated kidney…
2016 American Transplant Congress
Clinical Correlation Between Pairs of Kidneys Transplanted from the Same Donor.
A. Baheerathan, H. Beckwith, A. McLean, D. Taube, M. Willicombe.
Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
Introduction: Concordance of allograft outcomes between kidneys transplanted from the same donor has previously been reported. However recipient characteristics become increasingly important after the immediate…
2016 American Transplant Congress
Preimplantation and Post-Transplant Serial Biopsies of Standard and Extended Criteria Donor Kidneys: Intragraft Molecular Profiles and Effect of Different Immunosuppressive Protocols.
C. Mazeti,¹ H. Caldas,¹ I. Fernandes-Charpiot,² M. Baptista,² M. Abbud-Filho.^1,2,3
¹Laboratory of Immunology and Experimental Transplantation, Medical School, Sao Jose do Rio Preto, SP, Brazil; ²Department of Medicine/Nephrology, Medical School, Sao Jose do Rio Preto, SP, Brazil; ³Urology and Nephrology Institute, Urology and Nephrology Institute, Sao Jose do Rio Preto, SP, Brazil.
Background: Use of extended criteria donor kidneys (ECD) carries the fear of to transplant of inferior quality and therefore of high discard rate. Clinical tools…
2016 American Transplant Congress
Standardized Pre-Implantation Kidney Biopsies of Expanded Criteria Donors to Improve the Kidney Donor Profile Index (KDPI) for the Evaluation of Marginal Donors.
A. Sánchez-Escuredo,¹ A. Sagasta,² F. Diekmann,¹ I. Revuelta,¹ L. Rodas,¹ D. Paredes,³ M. Musquera,⁴ N. Esforzado,¹ M. Ricart,¹ F. Cofan,¹ V. Torregrosa,¹ J. Campistol,¹ M. Sole,² F. Oppenheimer.¹
¹Nephrology and Renal Transplant, Hospital Clínic, Barcelona, Spain; ²Pathology, Hospital Clínic, Barcelona, Spain; ³Transplant Foundation, Hospital Clínic, Barcelona, Spain; ⁴Urology, Hospital Clínic, Barcelona, Spain.
There is no consensus of selection criteria used to allocate renal transplants from expanded criteria donors (ECD). The Kidney Donor Profile Index (KDPI) has been…
2016 American Transplant Congress
Young Recipients Receiving Kidneys from Older Donors Have Poorer Allograft Outcomes.
A. Wardle, M. Willicombe, D. Goodall, A. McLean, D. Taube.
Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
Introduction: An increasing number of marginal donors are being used in order to expand the donor pool. Age is one of the major criteria in…
2016 American Transplant Congress
Outcomes of Liver Grafts from Donors with Very High Transaminases.
P. Martins, A. Rawson, P. Mahboub, B. Movahedi, N. Dolgin, I. Bruggenwirth, A. Bozorgzadeh.
Department of Surgery, Transplant Division, University of Massachusetts, Worcester, MA.
Introduction: Traditionally, elevation of transaminases has been broadly used as markers of hepatic ischemic injury and crucial parameters for liver graft assessment. We wanted to…