Articles tagged "Malignancy"

2022 American Transplant Congress
Transplant Combined with Neoadjuvant Therapy Improves Survival for Patients with Liver-Limited, Locally Advanced Intrahepatic Cholangiocarcinoma: A SEER Database Analysis
G. G. Panayotova¹, M. Javle², S. Pentakota¹, F. Paterno¹, A. Amin¹, L. Brown¹, S. Simonishvili¹, Y. Qin¹, T. Ayorinde¹, G. Prakash¹, C. Conrad³, J. V. Guarrera¹, K. E. Lunsford¹
¹Rutgers New Jersey Medical School, Newark, NJ, ²University of Texas, MD Anderson Cancer Center, Houston, TX, ³St. Elizabeth's Medical Center, Boston, MA
*Purpose: Preliminary single-center data suggest multimodal therapy may improve outcomes for patients with intrahepatic cholangiocarcinoma (iCCA) undergoing liver transplant (LT), particularly in the setting of…
2022 American Transplant Congress
Metastatic BK Virus-Associated Urothelial Carcinoma Originating in Renal Allograft
J. Torrealba¹, H. Jones¹, A. Bhakta², L. Jia¹, D. Wojciechowski²
¹Pathology, UT Southwestern, Dallas, TX, ²Internal Medicine, UT Southwestern, Dallas, TX
*Purpose: Cases of urinary tract carcinoma associated with BK virus have been reported in kidney transplant recipients; therefore, we postulate that BK virus may play…
2022 American Transplant Congress
Seroprevalence of HHV8 Among Donors and Recipients with HIV
P. H. Nambiar¹, T. Liang², J. D. Motter³, W. Werbel³, S. Mehta⁴, V. Kirchner⁵, M. Rana⁶, S. Florman⁷, J. Odim⁸, W. Miley⁹, N. Labo⁹, D. Whitby⁹, A. Massie¹⁰, D. Segev³, A. Tobian³, C. Durand²
¹Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, ²Medicine, Johns Hopkins University, Baltimore, MD, ³Johns Hopkins University, Baltimore, MD, ⁴New York University Langone Transplant Institute, New York, NY, ⁵University of Minnesota, Minneapolis, MN, ⁶Icahn School of Medicine at Mount Sinai, New York, NY, ⁷Mount Sinai Medical Center, New York, NY, ⁸National Institute of Health, Bethesda, MD, ⁹National Cancer Institute, Frederick, MD, ¹⁰Johns Hopkins School of Medicine, Baltimore, MD
*Purpose: Kaposi sarcoma (KS) can develop post-transplant via recipient HHV8 reactivation or donor-acquired HHV8. In the general US population, HHV8 seroprevalence is low (1-5%), yet…
2022 American Transplant Congress
Cutaneous Angiosarcoma in Solid Organ Transplant Recipients – Novel Case & Review of the Literature
S. M. Elzein, R. R. Caplan
Houston Methodist Hospital, Houston, TX
*Purpose: Cutaneous angiosarcoma, a rare and extremely aggressive malignant neoplasm, has been described in fewer than twenty-five solid organ transplant recipients to date. Secondary, or…
2022 American Transplant Congress
Risk of Post-Transplant Lymphoproliferative Disease After Anti-Thymocyte Globulin in Childhood Solid-Organ Transplant Recipients
A. M. McKay¹, C. Teoh¹, J. Vasilevska-Ristovka², J. Browne², T. Banh², A. Dipchand¹, V. Ng¹, M. Solomon¹, U. Allen¹, Y. Avitzur¹, R. Parekh³
¹Transplant & Regenerative Medicine Centre, The Hospital for Sick Children, Toronto, ON, Canada, ²Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada, ³Division of Nephrology, Department of Medicine, Women’s College Hospital and University Health Network, Toronto, ON, Canada
*Purpose: Determine if the use of anti-thymocyte globulin (ATG) in pediatric solid organ transplant recipients was associated with an increased risk of post-transplant lymphoproliferative disorder…
2022 American Transplant Congress
Risk of Tumor Recurrence, Functional Decline, and Metastatic Disease of Renal Transplant in Recipients with Hereditary Kidney Cancer: A Case Series
M. Antony, A. Chaurasia, N. Gopal, Z. Kozel, M. Linehan, M. Ball
Urologic Oncology Branch, National Cancer Institute, Bethesda, MD
*Purpose: Von Hippel-Lindau disease is a hereditary cancer syndrome characterized by bilateral, multifocal renal tumors and cysts. Advancements in nephron-sparing surgeries have improved functional and…
2022 American Transplant Congress
Kidney Transplantation in Patients Postradical Prostatectomy
S. Karhadkar, K. Wirshup, J. Kolansky, A. Gregor, J. Dawes, A. DiCarlo
Temple University Hospital, Philadelphia, PA
*Purpose: The population of the United States is aging. By the year 2050 those over 65 years of age are projected to make up 20.2%…
2022 American Transplant Congress
Donor-Derived Duodenal Adenocarcinoma of a Bladder-Drained Pancreas Allograft
D. Isaacson¹, J. Steggerda¹, Y. Xue¹, G. B. Auffenberg², N. N. Katariya³
¹Northwestern University, Chicago, IL, ²Urology of St. Louis, St. Louis, MO, ³Mayo Clinic, Phoenix, AZ
*Purpose: Donor-derived malignancies are rare but frequently present with aggressive pathology and high mortality rates [PMID 32627325]. The urologic literature demonstrates an increased risk of…
2022 American Transplant Congress
Characterizing the Landscape of Cancer Risk Following HLA-Incompatible Living Donor Kidney Transplantation
J. D. Motter¹, K. Jackson¹, K. Yu², R. M. Pfeiffer², A. Massie¹, J. Garonzik-Wang³, D. Segev¹, E. A. Engels²
¹Johns Hopkins University, Baltimore, MD, ²National Cancer Institute, Bethesda, MD, ³University of Wisconsin-Madison, Madison, WI
*Purpose: Incompatible living donor kidney transplant recipients (ILDKTr) require desensitization to facilitate transplantation across donor-specific antibody (DSA); however, this substantial upfront immunosuppression may result in…
2022 American Transplant Congress
Immunotherapy Before Solid Organ Transplantation: An International Transplant Community-Focused Survey
T. Ivanics¹, M. P. Claasen¹, D. Al-Adra², G. Sapisochin³
¹University of Toronto - University Health Network, Toronto, ON, Canada, ²Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, ³Multi-organ transplant program, University Health Network, Toronto, ON, Canada
*Purpose: The use of immunotherapy for cancer has increased and is expected to continue to grow. The outcomes after solid organ transplantation (SOT) in patients…