2019 American Transplant Congress
Assessing Discarded Human Liver Quality with Normothermic Ex-Vivo Liver Perfusion
Surgery, Washington University in St. Louis, St. Louis, MO
*Purpose: Normothermic Ex-vivo Liver Perfusion (NELP) of livers shows promising results in overcoming injuries that occur in deceased donor liver transplantation. The effect of NELP…2019 American Transplant Congress
Dynamic Characterization of Cells in the Perfusate from Cold Ischemic Liver Grafts
Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA
*Purpose: Injury during preservation is a complex process that affects graft function. A deeper understanding and better prediction of liver viability are demanded to improve…2019 American Transplant Congress
Correlation between Gene Expression and Cardiac Function in Ex Vivo Perfused Porcine Hearts
University of Alberta, Edmonton, AB, Canada
*Purpose: Cardiac transplantation is a life-saving intervention for advanced heart failure but it is limited by a shortage of suitable donor organs. Ex vivo heart…2019 American Transplant Congress
‘Back-to-Base’ Normothermic Clinical Liver Perfusion – Cold before NMP Does Not Compromise Protective Benefit
University of Alberta Hospital, Edmonton, AB, Canada
*Purpose: In previous clinical studies utilizing normothermic ex situ liver machine preservation, perfusion was initiated rapidly following organ procurement using a portable system transported to…2019 American Transplant Congress
Protective Effect of Ischemic-Free Liver Transplantation Technique on Distant Multiple Organ Function
*Purpose: Hypothermia, hypoxia and ischemia-reperfusion injury (IRI) in standard liver transplantation (SLT) are the main factors that affect graft function and cause damage to remote…2019 American Transplant Congress
Oxygenated Hypothermic Machine Perfusion of Kidneys Donated after Circulatory Death: An International Randomised Controlled Trial
*Purpose: An international, double-blinded, randomised, paired phase 3 trial designed to determine the effect on 1-year graft function of continuous oxygenated (HMPO) vs non-oxygenated hypothermic…2019 American Transplant Congress
Effectiveness Of The Vittal Viability Criteria During Ex Situ Normothermic Machine Perfusion To Discriminate Hepatobiliary Organ Injury And Investigation Of Biochemical Markers For Post-transplant Complications
Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom
*Purpose: The VITTAL (viability testing and transplantation of marginal livers) clinical trial demonstrated that ex situ end-ischaemic normothermic machine perfusion (NMP) allows functional assessment and…2019 American Transplant Congress
Combined Thoracic-Liver Transplants Using Normothermic Machine Perfusion for Liver Preservation: A Case Series
Henry Ford Transplant Institute, Detroit, MI
*Purpose: There is minimal data describing combined thoracic-liver transplants (tx) with normothermic machine perfusion (NMP) used for liver preservation as the thoracic tx is done.…2019 American Transplant Congress
Viability Testing and Transplantation of Marginal Donor Livers (VITTAL) Trial: Metabolomics of Ex Vivo Normothermically Machine Perfused Livers Discloses Molecular Signatures Predictive of Graft Viability and Post Transplant Outcomes
*Purpose: Donor organ shortage has led to increased reliance on high-risk livers for transplantation. Furthermore, emergence of machine perfusion has led to a paradigm shift…2019 American Transplant Congress
Long Term Cold Ischemia Time in Kidney Transplantation. The Role of Hypothermic Machine Perfusion
*Purpose: Hypothermic machine perfusion (HMP) of deceased donor kidneys is associated with a better outcome than static cold storage (SCS). Aim of this prospective study…
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