Articles tagged "Machine preservation"

2022 American Transplant Congress
Prolonged Preservation by Hypothermic Machine Perfusion Facilitates Logistics in Liver Transplantation: A European Observational Cohort Study
I. M. Brüggenwirth¹, M. Mueller², V. A. Lantinga¹, S. Camagni³, R. De Carlis⁴, L. De Carlis⁵, M. Colledan⁶, D. Dondossola⁷, M. Drefs⁸, J. Eden², D. Ghinolfi⁹, D. Koliogiannis¹⁰, G. Lurje¹¹, T. Manzia¹², D. Monbaliu¹³, P. Muisean¹⁴, D. Patrono¹⁵, J. Pratschke¹⁶, R. Romagnoli¹⁷, M. Rayar¹⁸, F. Roma¹⁴, A. Schlegel², P. Dutkowski², R. J. Porte¹, V. E. de Meijer¹
¹University Medical Center Groningen, Groningen, Netherlands, ²University Hospital Zurich, Zurich, Switzerland, ³ASST Papa Giovanni XXIII, Bergamo, Italy, ⁴ASST Grande Ospedale Metropolitano Niguarda, Niguarda, Italy, ⁵Niguarda Ca’ Granda Hospital, Niguarda, Italy, ⁶Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy, ⁷Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy, ⁸University of Munich, Munich, Germany, ⁹Azienda Ospedaliero Universitaria Pisana, Pisa, Italy, ¹⁰Hospital of the University of Munich, Munich, Germany, ¹¹Charité Universitätsmedizin Berlin, Berlin, Germany, ¹²Tor Vergata University, Rome, Italy, ¹³KU Leuven University Hospitals Leuven, Leuven, Belgium, ¹⁴Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, ¹⁵A. O. U. Città della Salute e della Scienza di Torino, Turin, Italy, ¹⁶Charite Universitatsmedizin Berlin, Berlin, Germany, ¹⁷AOU Città della Salute e della Scienza di Torino, Turin, Italy, ¹⁸CHU Pontchaillou, Rennes, France
*Purpose: A short period (1-2 hours) of hypothermic oxygenated machine perfusion (HOPE) after static cold storage is safe and reduces ischemia-reperfusion injury-related complications after liver…
2022 American Transplant Congress
Pump Resistance Thresholds and Graft Outcomes in Machine Perfused Kidneys-A Single Center Retrospective Study
S. Sivan, J. Gaynor, M. Tabbara, G. Ciancio
Univ of Miami Miller School of Medicine, Miami, FL
*Purpose: Perfusion parameters are increasingly used to assess the quality of organs and to make decisions about discarding the organ. Resistive index(RI) has been an…
2022 American Transplant Congress
Development of Ex-Situ Hypothermic and Normothermic Reperfusion as an Innovative Method to Preserve an Assess Uterus: A Preliminary Result
L. Dion¹, E. Loiseau², B. Mesnard³, G. Blancho⁴, T. Thubert⁵, J. Hervouet⁴, D. Minault⁴, S. Le Bas-Bernardet⁶, R. Josien⁶, V. Lavoué¹, J. Branchereau⁷
¹Gynécologie, CHU Rennes, Rennes, France, ²Gynécologie, CHU Nantes, Nantes, France, ³Department of Urology, Chu Nantes, Nantes Université, ITUN, Nantes, France, Nantes, France, ⁴CHU Nantes, Nantes, France, ⁵Gynécologie, CHU Nantes, nantes, France, ⁶Université de Nantes, Nantes, France, ⁷Urologie, CHU Nantes, Nantes, France
*Purpose: Uterine transplantation is a new surgical approach in transplantation community. It can be performed after living donation (LD) or Dead-Brain Donation (DBD). Static cold…
2022 American Transplant Congress
Normothermic Machine Perfusion (NMP) Improves Access to Transplantation for Late Liver Re-Transplant Candidates
D. Sneiders¹, H. Lembach¹, A. Hann¹, A. Nutu¹, J. Hodson¹, J. Isaac¹, R. Taylor², M. Armstrong¹, T. Perera¹, H. Hermien¹
¹Queen Elizabeth Hospital, Birmingham, United Kingdom, ²NHS Blood and Transplant, bristol, United Kingdom
*Purpose: Late liver re-transplantation (LLrT) is a complex surgical procedure. Candidates for LLrT spend longer on the waitlist than primary transplant candidates due to selectivity…
2022 American Transplant Congress
Outcomes After Deceased Donor Kidney Transplantation Utilizing Kidney Allografts with Marginal Perfusion Parameters: A Single-Center Experience
P. N. Chotai¹, A. Logan², F. Siddiqui³, A. Schenk⁴, G. Bumgardner⁵, G. L. Brock², A. El-Hinnawi⁵, A. Rajab⁶, K. Washburn⁷, N. Singh²
¹Division of Transplantation, Department of General Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, ²The Ohio State University Wexner Medical Center, Columbus, OH, ³Ohio State University, Bloomfield, NJ, ⁴Ohio State University Wexner Medical Center, Bexley, OH, ⁵Ohio State University, Columbus, OH, ⁶Ohio State University Wexner Medical Center, Columbus, OH, ⁷The Ohio State University, Columbus, OH
*Purpose: To study outcomes of deceased donor kidney transplantation (DDKT) in recipients of kidney allografts with poor perfusion parameters.*Methods: This is a retrospective, single center…
2022 American Transplant Congress
Performance of Aged Liver Grafts in a Rat Model of Normothermic Ex Vivo Liver Machine Perfusion
S. Moosburner¹, M. Zimmer¹, J. M. Gassner¹, N. Roschke¹, N. Berndt², J. Michelotto¹, K. H. Hillebrandt¹, J. Pratschke¹, I. M. Sauer¹, N. Raschzok¹
¹Department of Surgery, Experimental Surgery, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, ²Institute of Biochemistry, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany
*Purpose: We aimed to characterize the performance of old vs. young liver grafts in a standardized rat model of normothermic ex vivo liver machine perfusion…
2022 American Transplant Congress
Organ Tracking Combined with Real-Time Communication to Reduce Organ Shipment Delays and Cit: The First Report of a Comprehensive, Scalable System for Organ Tracking and Communication in the United States
A. Melia¹, S. Pankow¹, C. Paydenkar¹, P. Summers¹, J. Scalea²
¹MediGO, Inc., Baltimore, MD, ²Surgery, University of Maryland, Baltimore, MD
*Purpose: Recent organ allocation strategies have elevated the complexity of organ shipment, increasing the organ travel time and distance. Despite these changes, logistics, time, and…
2022 American Transplant Congress
Normothermic Machine Perfusion in Liver Transplantation – Seven Year Experience at a Single North American Centre
J. Hefler¹, D. L. Izuierdo¹, G. Meeberg², M. Bral¹, B. Anderson¹, K. Dajani¹, N. Kneteman¹, D. L. Bigam¹, A. Shapiro¹
¹Department of Surgery, University of Alberta, Edmonton, AB, Canada, ²Alberta Health Services, Edmonton, AB, Canada
*Purpose: Machine perfusion for preservation of liver grafts before transplantation has risen in prominence over the past decade. Normothermic machine perfusion (NMP), in particular, has…
2022 American Transplant Congress
Early Experience Of 48-hour Normothermic Machine Perfusion In Human Kidneys Applying Urine Recirculation
F. Messner¹, S. Gasteiger¹, M. Pühringer-Sturmayr¹, A. Soleiman¹, D. Öfner¹, S. Schneeberger¹, A. Weissenbacher²
¹Medical University of Innsbruck, Innsbruck, Austria, ²Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria
*Purpose: Normothermic machine perfusion (NMP) of the kidney has been studied extensively during the past decade. Short-term kidney NMP has demonstrated promising results, however currently…
2021 American Transplant Congress
Thrombolytic Therapy During Ex-Vivo Normothermic Machine Perfusion of Human Livers Reduces Peribiliary Vascular Plexus Injury
O. Haque¹, S. Raigani², I. Rosales², C. Carroll², T. M. Coe², S. Baptista², H. Yeh², K. Uygun², J. F. Markmann²
¹Surgery, Beth Israel Deaconess Medical Center, Boston, MA, ²Massachusetts General Hospital, Boston, MA
*Purpose: A major limitation in expanding the use of DCD livers in transplantation are the higher rates of graft failure secondary to ischemic cholangiopathy. Warm…