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Articles tagged "Machine preservation"

  • 2015 American Transplant Congress

    Ex Vivo Lung Perfusion: Revisit to the Optimal Oxygenation Circulating Lungs for Graft Preservation

    K. Noda, S. Haam, J. D'Cunha, J. Luketich, C. Bermudez, N. Shigemura.

    Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA.

    AimAccumulating evidence supports increasing the role of ex vivo lung perfusion (EVLP). However, there are evidenced limitations as well as the adverse effects of current…
  • 2015 American Transplant Congress

    Correlation Between Level of Biomarkers Measured in Perfusate of Machine-Preserved ECD/DCD Kidneys and Post-Transplant Graft Function

    E. Ablorsu,1 S. Zouwail,2 P. Laftsidis,1 B. Cook,1 L. Szabo.1

    1Cardiff Transplant Unit, University Hospital for Wales, Cardiff, United Kingdom; 2The Medical Biochemistry and Immunology Department, University Hospital for Wales, Cardiff, United Kingdom.

    Background:DCD and ECD kidneys are associated with higher risk of failure compare to SCD kidneys. Therefore we see increasing need to identify sensitive tool to…
  • 2015 American Transplant Congress

    Pre-Trasplant Perfusion With Mesenchymal Stromal Cells of Renal Graft Prevents Ischemia Injury Upregulating Gene Involved in Energy Saving

    V. Corradetti,1 S. Milanesi,1 E. Pattonieri,1 C. Rocca,1 T. Valsania,1 M. Gregorini,1 L. De Cecco,2 I. Benzoni,3 C. Bianco,3 M. Avanzini,4 M. Maestri,3 P. Esposito,1 T. Rampino,1 A. Dal Canton.

    1Unit of Nephrology, Dialysis and Transplantation, IRCCS Fondazione Policlinico San Matteo And University of Pavia, Pavia, Italy; 2Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milano, Italy; 3Unit of General Surgery, IRCCS Fondazione Policlinico San Matteo And University of Pavia, Pavia, Italy; 4Cell Factory Pediatric Oncohaematology, IRCCS Fondazione Policlinico San Matteo, Pavia, Italy.

    Background. Kidney ischemia from Donation after Circulatory Death shifts cells to anaerobic metabolism. Mesenchymal Stromal Cells (MSC) have immunomodulatory properties that are mediated by soluble…
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