Articles tagged "Machine preservation"

2022 American Transplant Congress
Maturation and Evaluation of 3D Printed Bionic Pancreas with a Dedicated Bioreactor
A. Berman¹, M. Klak², T. Dobrzanski³, T. Bryniarski³, M. Kolodziejska³, G. Tymicki³, M. Wszola³
¹Polbionica Ltd., Warsaw, Poland, ²Foundation for Research and Science Development, Warsaw, Poland, ³Foundation of Research and Science Development, Warsaw, Poland
*Purpose: The technology of 3D printing of bionic organs gives an opportunity to solve the problems of classical transplantology, such as the shortage of organs,…
2022 American Transplant Congress
Does Machine Perfusion of Heart for Donation After Cardiac Death (DCD) Transplantation Affect Other Organ Outcomes?
R. Misawa¹, K. Okumura², H. Sogawa¹, G. Veillette¹, A. Dhand³, R. Bodin⁴, D. C. Wolf⁴, B. Partiula⁴, D. John¹, T. Diflo⁵, S. Nishida¹
¹Department of Surgery, Transplant, Westchester Medical Center/New York Medical College, Valhalla, NY, ²Surgery, Westchester Medical Center/New York Medical College, Valhalla, NY, ³Department of Medicine, Westchester Medical Center/New York Medical College, Valhalla, NY, ⁴Medicine, Westchester Medical Center/New York Medical College, Valhalla, NY, ⁵Westchester Medical Center/New York Medical College, Valhalla, NY
*Purpose: Machine perfusion of heart for donation after cardiac death (DCD) transplants is being increasingly utilized. Initial protocol of the heart machine perfusion for the…
2022 American Transplant Congress
Role of Mitochondrial Transplantation in Enhancing Liver Regeneration Following Partial Hepatectomy
G. Lamanilao¹, C. Watkins¹, C. Kuscu¹, C. Kuscu¹, J. Eason², A. Bajwa¹
¹Transplant Research Institute, James D. Eason Transplant Institute, Department of Surgery, The University of Tennessee Health Science Center, Memphis, TN, ²University of Tennessee/Methodist Transplant Institute, Memphis, TN
*Purpose: Therapeutic strategies that accelerate the rate of liver regeneration following partial hepatectomy (PH) should be developed to reduce occurrences of small for size syndrome…
2022 American Transplant Congress
Pre-Transplant Ex-Vivo Analysis of Kidney Vasculature and Perfusion Using Contrast Computed Tomography
A. Feizi¹, J. R. DiRito¹, M. Harris¹, J. C. Stendahl¹, S. Spindler¹, C. M. Edwards¹, T. Lysyy¹, S. Lee¹, N. Boutagy¹, A. Fehér¹, P. Yoo¹, S. A. Hosgood², D. C. Mulligan¹, M. L. Nicholson², A. J. Sinusas¹, D. J. Haakinson¹, G. T. Tietjen¹
¹Yale School of Medicine, New Haven, CT, ²University of Cambridge, Cambridge, United Kingdom
*Purpose: Ex-vivo normothermic perfusion (NMP) has been developed with the goal of improving viability of the thousands of donated organs that are declined for transplant…
2022 American Transplant Congress
Predictors of Delayed Kidney Graft Function Following Combined Liver and Kidney Transplantation
P. Vincenzi¹, J. Gaynor², R. Vianna³, G. Ciancio³
¹General Surgery, Ospedali Riuniti Marche Nord, Pesaro, Italy, ²General Surgery, Miami Transplant Institute, Miami, FL, ³Transplant Surgery, Miami Transplant Institute, Miami, FL
*Purpose: Combined liver and kidney transplantation (CLKT) improves the survival in liver transplant recipients with renal dysfunction. However, kidney DGF (kDGF) still represents a common…
2022 American Transplant Congress
Lung Transplantation After Ex Vivo Lung Perfusion, Early and Mid-Term Outcomes
K. Noda, E. G. Chan, J. Ryan, M. Furukawa, J. D. Luketich, P. G. Sanchez
Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA
*Purpose: The safety of lung transplantation using ex vivo lung perfusion (EVLP) has been confirmed by multiple clinical studies, however, limited evidence is currently available…
2022 American Transplant Congress
Normothermic Ex Vivo Pancreas Perfusion for the Preservation of Porcine Pancreas Grafts
C. Parmentier, S. Ray, L. Mazilescu, M. Kawamura, T. Goto, Y. Noguchi, B. Arulratnam, S. Ganesh, M. Selzner, T. Reichman
Multi-Organ Transplant Department, University Health Network - Toronto General Hospital, Toronto, ON, Canada
*Purpose: The purpose of this study was to develop a stable porcine model for normothermic ex-vivo pancreas perfusion (NEVPP) for the preservation of grafts with…
2022 American Transplant Congress
Novel Portable Hypothermic Cardiac Preservation Device Enhances Cardiac Viability and Function of the Isolated Porcine Hearts
K. Andrijauskaite, R. J. Veraza, R. P. Lopez, E. C. Cisneros, I. J. Jessop, M. D. Watt, L. Bunegin
Vascular Perfusion Solutions, Inc, San Antonio, TX
*Purpose: Cardiac heart transplantation is the gold standard for treating end-stage heart failure; however, the list of patients waiting for heart transplants continues to increase.…
2022 American Transplant Congress
Tissue Edema Following Hypothermic Machine Perfusion of a Small Animal Hind Limb Graft
D. Yoeli, Y. Wang, B. Li, J. Huang, S. Jain, Z. Wang, N. Nakra, N. Limon De La Rosa, K. Rampalski, A. Su, D. Mathes, K. Washington, E. Farkash, A. Jani, C. Huang
University of Colorado Anschutz Medical, Aurora, CO
*Purpose: The aim of this study was to evaluate the capability of preserving a small animal hind limb graft for 24 hours with hypothermic machine…
2022 American Transplant Congress
Enhanced Delivery of Nanomedicine to Human Kidney During Ex Vivo Perfusion
C. Albert¹, L. Bracaglia¹, A. Koide², J. R. DiRito¹, T. Lysyy¹, E. Christopher¹, J. Grundler¹, J. T. Langford¹, D. Haakinson¹, J. S. Pober¹, W. M. Saltzman¹, S. Koide², G. Tietjen¹
¹Yale University, new haven, CT, ²Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY
*Purpose: An efficient delivery of therapeutic agents to graft endothelial cells (ECs) prior to transplantation could render organs more resistant to injury, improving clinical outcomes…

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