2019 American Transplant Congress
Undernutrition and Leptin Deficiency Modulates T Cell Immunity in Transplantation
1Pediatrics, Duke University, Durham, NC, 2Surgery, Duke University, Durham, NC
*Purpose: We have previously shown an association between undernutrition and the development of viremia in transplanted children. While undernutrition is associated with impaired T cell…2019 American Transplant Congress
Absence of Protective Innate Lymphoid Cell Type 3 (ILC3) and Persistence of Proinflammatory Innate Lymphoid Cell Subsets Immediately Post-Transplant Plays a Appreciable Role in Early Intestinal Barrier Dysfunction
Georgetown University, Washington, DC
*Purpose: Innate lymphoid cells (ILCs) , the most recently described family of lymphoid cells, play fundamental roles in mucosal barrier immunity, tissue homeostasis, and immune…2019 American Transplant Congress
B Cell Immunophenotypes in Transplantation
*Purpose: B cells and B cell responses have been associated with favorable outcomes of transplantation in some setting and unfavorable outcomes in others. For example,…2019 American Transplant Congress
Post-Transplant Lymphopenia is Associated with Higher Risk of Graft Failure, Death and Viral Infections
*Purpose: The transplantation field needs biomarkers to assess the level of immunosuppression. In this study, we aimed to analyze the independent correlation between the number…2019 American Transplant Congress
High Prevalence of Allergic Disorders but No Specific Immune Phenotype Pattern in Children Awaiting Transplantation
*Purpose: Allergic disorders (AD) occur more frequently in children after transplantation (Tx) compared to healthy children, reflecting an imbalance of the immune system in the…2019 American Transplant Congress
Transplantation Alone Induces Myeloid-Derived Suppressor Cells Which Can Suppress T Cell Responses
University of Maryland, Baltimore, MD
*Purpose: Myeloid-derived suppressor cells (MDSC) are a naturally occurring, heterogeneous population of highly immunosuppressive CD11b+GR-1+ cells that expand in response to inflammatory conditions. MDSCs develop…2019 American Transplant Congress
Myeloid Derived Suppressor Cells (MDSC) Home to the Allograft and Can Control T Cell Responses
University of Maryland, Baltimore, MD
*Purpose: Myeloid-derived suppressor cells (MDSC) are a naturally occurring, heterogeneous population of highly immunosuppressive CD11b+GR-1+ myeloid cells that expand in response to inflammatory conditions. Although…2019 American Transplant Congress
The Inverted Renal CD4/CD8 Ratio Associated with the Development of Transplant Glomerulopathy and Arteriosclerosis
*Purpose: Inversion of the CD4/CD8 ratio (2019 American Transplant Congress
Thymoglobulin Induction with Tacrolimus and Everolimus Maintenance Therapy in Elderly Kidney Transplantation Results in Prolonged Lymphocyte Depletion and Do Not Favor Regulatory Profile
*Purpose: Despite the growing number of elderly kidney transplant (Ktx) recipientes few studies describe the effects of immunosuppression on this group. We evaluated the immunological…2019 American Transplant Congress
Single-center Retrospective Analysis of Prophylaxis and Treatment of Pneumocystis Carinii Pneumonia in Patients with Poor Renal Function
Kidney-Pancreas Transplant Department., Tianjin First Central Hospital, Tianjin, China
*Purpose: Pneumocystis carinii pneumonia (PcP) is a potentially life-threatening complication in renal transplant recipients. Although the use of trimethoprim-sulfamethoxazole (TMP-SMX) chemoprophylaxis after kidney transplantation is…
American Transplant Congress abstracts