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Articles tagged "Lung"

  • 2017 American Transplant Congress

    Waitlist and Post-Lung Transplant Mortality Vary by Diagnosis for a Given Lung Allocation Score.

    H. Maredia, M. Bowring, A. Massie, S. Oyetunji, C. Merlo, R. Higgins, D. Segev, E. Bush.

    JHU, Baltimore

    The lung allocation score (LAS) is used to prioritize candidates based on predicted one-year waitlist mortality and post-transplant survival. Lung diagnosis is factored into LAS,…
  • 2017 American Transplant Congress

    Age and Gender Disparities in Post-Lung Transplant Mortality.

    H. Maredia, M. Bowring, A. Massie, S. Oyetunji, C. Merlo, R. Higgins, D. Segev, E. Bush.

    JHU, Baltimore

    Gender, race, and age have been associated with health disparities, including in post-transplant outcomes. Given disparities in post-lung transplant outcomes are not well-understood, we assess…
  • 2017 American Transplant Congress

    Is Lung Allocation Score Associated with Waitlist and Post-Transplant Survival?

    H. Maredia, M. Bowring, A. Massie, S. Oyetunji, C. Merlo, R. Higgins, D. Segev, E. Bush.

    JHU, Baltimore

    The lung allocation score (LAS) prioritizes patients based on predicted one-year waitlist and post-transplant mortality. However, for a given diagnosis, it is unclear whether LAS…
  • 2017 American Transplant Congress

    Age and Race Disparities Among Pediatric and Adult Cystic Fibrosis Lung Transplant Recipients.

    H. Maredia, M. Bowring, A. Massie, S. Oyetunji, C. Merlo, R. Higgins, D. Segev, E. Bush.

    JHU, Baltimore

    Pediatric cystic fibrosis (CF) patients have a post-lung transplant survival disadvantage compared to adults. However, whether race and age are risk factors associated with post-transplant…
  • 2017 American Transplant Congress

    Impact of Caregiver on 30 Day Readmission After Lung Transplant.

    T. Coco, C. Keller, F. Alvarez, D. Erasmus, J. Mallea.

    Department of Transplantation, Mayo Clinic Florida, Jacksonville, FL

    The type of primary caregiver has been associated with long-term outcomes after lung transplantation. There is no data on the impact of caregiver associated with…
  • 2016 American Transplant Congress

    Multiplex Profiling of Plasma Proteins After Xenogenic Lung Exposure.

    A. Azimzadeh,1 N. Cheng,1 X. Cheng,1 E. Schwartz,1 L. Burdorf,1 S. Dahi,1 N. Kubicki,1 D. Parsell,1 T. Zhang,1 D. Cooper,2 C. Phelps,3 D. Ayares,3 R. Pierson III.1

    1Univ. Of Maryland, Baltimore, MD; 2University of Pittsburgh, Pittsburgh, PN; 3Revivicor, Blacksburg, VA.

    Background: Porcine lungs exhibit injury by human blood and are only partially protected in GalTKO organs with additional human membrane cofactor protein (hCD46). Residual injury…
  • 2016 American Transplant Congress

    Positive Impact of a Pilot Pharmacist-Run Diabetes Pharmacotherapy Clinic in Solid Organ Transplant Recipients.

    D. Newland, A. Edwards, R. Hall, P. Maxwell.

    University Transplant Center, University Health System and The University of Texas Health Science Center at San Antonio, San Antonio, TX.

    Background: Post-transplant diabetes mellitus (PTDM) can lead to significant morbidity and cardiovascular death with a functioning graft. A paucity of literature exists regarding glycemic control…
  • 2016 American Transplant Congress

    Metallothionein Accelerates Anti-MHC Induced Small Airway Obliteration and Fibrosis by Negatively Regulating IL-10 and Regulatory Cells.

    D. Nayak,1,2 F. Zhou,1 N. Benshoff,1 T. Mohanakumar.1,2

    1Washington Univ Sch Med, St. Louis, MO; 2Norton Thoracic Institute, St. Joseph Hospital, Phoenix, AZ.

    Development of bronchiolitis obliterans syndrome (BOS), chronic lung allograft rejection, is a major obstacle to long-term success from lung transplantation. De novo antibodies (Abs) to…
  • 2016 American Transplant Congress

    Microarray Analysis of Transbronchial and Mucosal Biopsies in Lung Transplant Recipients Detects Molecular Changes of T-Cell Mediated Inflammation.

    K. Halloran,1 J. Chang,2 V. Ramassar,2 J. Weinkauf,1 A. Kapasi,1 D. Lien,1 J. Reeve,2 P. Halloran.1,2

    1Medicine, University of Alberta, Edmonton, Canada; 2Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, Canada.

    Purpose: The main diagnostic platform for rejection in lung transplant recipients is histology of transbronchial biopsies (TBB), a test with a poor performance and safety…
  • 2015 American Transplant Congress

    Mesenchymal Stem Cells Prevent Cold Ischemia-Reperfusion Injury in Lung Transplants

    H. Wang,1,2 W. Tian,1 Y. Liu,3 X. Dai,1 G. Li,3 T. Liu,1,2 Z. Zhang,1,2 C. Du.4

    1Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, China; 2Tianjin General Surgery Institute, Tianjin, China; 3Department of Biology, Tianjin Medical University, Tianjin, China; 4Department of Urologic Sciences, The University of British Columbia, Vancouver, BC, Canada.

    Background: Cold ischemia-reperfusion injury (IRI) is a major cause of graft failure in lung transplantation. Despite therapeutic benefits of mesenchymal stem cells (MSCs) in attenuating…
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