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Articles tagged "Lung infection"

  • 2018 American Transplant Congress

    In Vitro Evaluation of Antibiotic Persistence in Pseudomonas aeruginosa and Staphylococcus aureus Isolates from Cystic Fibrosis Patients

    J. Fose, D. Bruckbauer, M. Jorgenson, W. Rose.

    UW Hospital & Clinics, Madison; UW School of Pharmacy, Madison.

    Purpose: The mechanisms of antibiotic persistence in immunosuppressed populations are not fully understood. Patients with cystic fibrosis (CF), both the pre-transplant and post-transplant phase often…
  • 2017 American Transplant Congress

    Diagnostic Bronchoscopy in Kidney Transplant Recipients with Acute Respiratory Failure: Risk or Value?

    D. Khadzhynov, J. Deissler, F. Halleck, L. Lehner, K. Budde, O. Staeck.

    Nephrology, Charité Universitaetsmedizin, Berlin, Germany

    Introduction:Few data evaluates the differential diagnostic value of bronchoalveolar lavages (FO-BAL) in kidney transplant recipients (KTR) with acute respiratory failure (ARF). We describe the results…
  • 2016 American Transplant Congress

    An Analysis of Non-Tuberculous Mycobacteria (NTM) Infection and Colonization in Lung Transplant Recipients (LTRs) Post-Transplant: A Single Center Matched Cohort Study.

    H. Kozlowski,1,2 D. Kabbani,3 C. Chaparro,1,2 L. Singer,1,2 C. Rotstein,1,2 S. Keshavjee,1,2 S. Husain.1,2

    1University of Toronto, Toronto, ON, Canada; 2Toronto General Hospital, Toronto, ON, Canada; 3University of Alberta, Edmonton, AB, Canada.

    PurposeNTM is a common infection after Lung transplantation. The role of presence of granuloma in the explanted lungs of LTRs in subsequent development of infection…
  • 2016 American Transplant Congress

    Susceptibility Patterns of Pre-Transplant Pseudomonas and Post-Lung Transplant Outcomes in Patients with Cystic Fibrosis.

    S. Pouch,1 E. Lease,2 T. Bogdanovich,3 D. Ho,4 R. Miller,5 M. Estabrook,6 T. Babu,7 C. Kotton,7 C. Shaver,8 L. Thomas,8 S. Aslam,9 T. McCarty,10 J. Garcia-Diaz,11 K. Doucette,12 S. Kirkby,13 D. van Duin.14

    1Ohio State University, Columbus, OH; 2University of Washington, Seattle, WA; 3University of Pittsburgh, Pittsburgh, PA; 4Stanford University, Stanford, CA; 5University of Iowa, Iowa City, IA; 6Washington University St. Louis, St. Louis, MO; 7Massachusetts General Hospital, Boston, MA; 8Vanderbilt University, Nashville, TN; 9University of California San Diego, San Diego, CA; 10University of Alabama, Birmingham, AB; 11Ochsner Clinic Foundation, New Orleans, LA; 12University of Alberta, Edmonton, AB, Canada; 13Nationwide Children's Hospital, Columbus, OH; 14University of North Carolina, Chapel Hill, NC.

    Background: The impact of pre-lung transplant (LT) pan-drug-resistant Pseudomonas aeruginosa (PDR PsA) colonization on post-LT mortality and bronchiolitis obliterans syndrome (BOS) rates in cystic fibrosis…
  • 2016 American Transplant Congress

    Resolution of Undefined Etiology of Respiratory Infections in Lung Transplant Patients with Unbiased Metagenomic Sequencing.

    N. Mueller,1 D. Lewandowska,2 B. Ruehe,2 P. Schreiber,1 O. Zagordi,2 F. Geissberger,2 M. Schuurmans,3 M. Greiner,1 A. Zbinden,2 J. Boeni,2 C. Benden,3 A. Trkola,2 M. Huber.2

    1University Hospital Zurich, Division of Infectious Diseases, Zurich, Switzerland; 2University of Zurich, Institute of Medical Virology, Zurich, Switzerland; 3University Hospital Zurich, Division of Pulmonary Medicine, Zurich, Switzerland.

    Study Purpose A high number of post-transplant infections with respiratory symptoms remain unresolved, despite routine testing for the common respiratory viruses. Using an open metagenomic…
  • 2016 American Transplant Congress

    A 5-Year Multicenter Evaluation of Seasonal Influenza Infection in Transplant Recipients.

    D. Kumar,1 E. Cordero,4 E. Blumberg,2 A. Limaye,5 M. Levi,7 L. Danziger-Isakov,9 J. Englund,8 S. Husain,1 F. Silveira,10 G. Reid,6 T. Sharma,3 A. Humar.1

    1UHN, Toronto, Canada; 2UPenn, Philadelphia; 3BCH, Boston; 4REIPI, Seville, Spain; 5UoWMC, Seattle; 6LUMC, Chicago; 7UCD, Denver; 8SCH, Seattle; 9CCHMC, Cincinnati; 10UPMC, Pittsburgh.

    Background:Seasonal influenza infection may cause significant morbidity and mortality in transplant patients. However, there are limited prospective data on clinical presentations and determinants of outcomes.…
  • 2015 American Transplant Congress

    Epidemiology and Outcomes of Non Tuberculous Mycobacterial (NTM) Infections in Solid Organ Transplant (SOT) Recipients

    I. George, C. Santos, M. Olsen, T. Bailey.

    Infectious Diseases, Washington University School of Medicine, St. Louis, MO.

    Background: NTM are uncommon causes of infection in SOT recipients but may cause significant morbidity and mortality.Methods: A retrospective cohort of all patients who underwent…
  • 2015 American Transplant Congress

    Respiratory Infections Following Lung Transplantation Leads to De Novo Development of Antibodies to Both Donor HLA and Lung Associated Self-Antigens and Increases the Risk for Bronchiolitis Obliterans Syndrome

    K. George,1 M. Gunasekaran,1 M. Sharma,1 F. Zhou,1 A. Limaye,3 R. Hachem,2 T. Mohanakumar.1

    1Surgery, Washington Univ, St. Louis, MO; 2Medicine, Washington Univ, St. Louis, MO; 3Medicine, Univ Washington, Seattle, WA.

    Background: It is accepted that lower respiratory tract infections (LRI) post lung transplantation (LTx) are a risk factor for the development of Bronchiolitis Obliterans Syndrome…
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