2022 American Transplant Congress
Designing Continuous Distribution for Liver Allocation
*Purpose: The continuous distribution framework is required for all future organ allocation policies. Continuous distribution changes the allocation paradigm, prioritizing candidates according to a composite…2022 American Transplant Congress
Portal Vein Thrombosis and DCD Liver Transplantation: Dangerous Combination or Clinical Opportunity?
*Purpose: Individually, recipient portal vein thrombosis (PVT) and donation after circulatory death (DCD) allografts are associated with a higher risk of poor deceased donor liver…2022 American Transplant Congress
Non-Invasive Assessment of Hepatic Ischemia-Reperfusion Injury Using Dynamic Contrast Enhanced-MRI and T2 Mapping
*Purpose: Hepatic ischemia-reperfusion injury (IRI) is a consequence of liver transplantation and hepatectomy that varies in severity and clinical significance. The diagnosis is made based…2022 American Transplant Congress
Optimization of Human Liver Organoid Model for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis
*Purpose: The aim of our project is to develop an in vitro 3D human liver organoid (3D-HLO) model for studying nonalcoholic fatty liver disease (NAFLD)…2022 American Transplant Congress
18 Month Review of Liver Acuity Circles Allocation
*Purpose: Acuity circles (AC) allocation was implemented on 2/4/2020 with a goal of removing DSA and region from liver allocation and broadening the distribution of…2022 American Transplant Congress
Controlling Instability at Reperfusion: Another Benefit of Normothermic Machine Perfusion Using OCS Liver
*Purpose: Organ Care System (OCS) Liver is a portable ex-vivo normothermic liver perfusion device recently shown to provide superior donor organ preservation. The impact of…2022 American Transplant Congress
Physicians Are Perfectionists and Patients Are Pragmatic? Comparing Physician and Patient Definitions of Success in Liver Transplantation
1Ohio State University, Columbus, OH, 2The Ohio State University, Columbus, OH
*Purpose: The purpose of this study was to compare and contrast patient and physician perceptions of success one year after liver transplantation.*Methods: This was a…2022 American Transplant Congress
Type 1 Innate Lymphoid Cells Are Critical Pro-Inflammatory Effector Cells in a Fatty Liver Mouse Model of Ischemia-Reperfusion Injury
MedStar Georgetown Transplant Institute, Washington, DC
*Purpose: Innate lymphoid cells (ILCs), the most recently described family of lymphoid cells, play fundamental roles in tissue homeostasis through the production of key cytokine…2022 American Transplant Congress
Disparities in Liver Transplant Access for HCC Patients Based on Patient Blood Type and the Intensity of Competition for Organs Under MMAT-3
University of Southern California, Los Angeles, CA
*Purpose: Recent policy changes (acuity circles and MMAT-3 for HCC MELD exception) aimed to reduce geographic disparities in access to liver transplant (LT) and mitigate…2022 American Transplant Congress
Organ Care System Use in Liver Transplantation Shifts Preservation-Reperfusion Injury in Time and Space
Department of Transplant Pathology, University of Pittsburgh, Pittsburgh, PA
*Purpose: Liver allograft ischemia-reperfusion injury (IRI) causes early allograft dysfunction (EAD). The TransMedics Organ Care System (OCS) PROTECT trial for liver transplantation (NCT02522871) revealed that…
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