2022 American Transplant Congress
On the Circuit: Intra-Operative CRRT in Pediatric Liver Transplant Recipients with Acute Kidney Injury
*Purpose: Acute renal failure is common in pediatric patients undergoing liver transplantation (LT), with an incidence of 17-55%. Fluid, metabolic and acid-base aberrancies are often…2022 American Transplant Congress
The Liver Regenerative Effect of Substance P After Major Hepatectomy in Rat Models
*Purpose: The hepatic damages are inevitable under liver surgery. Therefore, post-hepatectomy liver failure remains one of the most dangerous and lifethreatening complications of hepatectomy. The…2022 American Transplant Congress
Axl and MerTK Regulate the Activation of Liver Ischemia Reperfusion Injury by Upregulating Il-13 in Kupffer Cells
*Purpose: Ischemia reperfusion injury (IRI) remains an unresolved clinical problem. A sterile inflammatory response drives the disease pathogenesis. Although mechanisms of liver innate immune activation…2022 American Transplant Congress
Perfusate Il-6 Levels During Liver Nmp Are Predictive For Hemodynamic Response And Catecholamine Demand After Reperfusion In The Recipient
*Purpose: Normothermic liver preservation (NMP) has become a clinical routine at several transplant centres. Reperfusion-syndrome occurs less often in recipients of NMP-livers compared to cold…2022 American Transplant Congress
Locoregional Therapy and Long-Term Post-Transplant Outcomes for HCC Liver Transplant Recipients
Johns Hopkins Medical Institutions, Baltimore, MD
*Purpose: In last decade, locoregional therapy (LRT) have been widely used to downstage HCC patients in order to qualify for liver transplantation. Large-scale direct comparisons…2022 American Transplant Congress
Portal Hypertension Inhibits the Antitumor Effect of Liver-Resident NK Cells Through IL-33 Signal
Hiroshima University, Hiroshima, Japan
*Purpose: Portal vein hypertension (PHT) after living donor liver transplantation (LDLT) is known to have associated with poor prognosis. Among patients with hepatocellular carcinoma (N=…2022 American Transplant Congress
Pre-Transplantation Liver Immunoadsorption Reduces Liver-Specific Antibody and Complement Deposition without Prolonging Survival in Porcine to Baboon Liver Xenotransplantation
1Massachusetts General Hospital/Harvard Medical School, Boston, MA, 2eGenesis, Inc, Cambridge, MA
*Purpose: Triple knock-out pigs lacking GGTA1, β4GALNT2, CMAH genes are hypothesized to be the optimal donor for human xenotransplantation, however there is evidence that TKO…2022 American Transplant Congress
Gsk3beta Regulates the Resolution of Liver Ischemia Reperfusion Injury via MerTK
*Purpose: We have shown previously that glycogen synthase kinase β (Gsk3β) regulates liver inflammatory activation against ischemia/reperfusion injury (IRI). The question of whether it also…2022 American Transplant Congress
Disparities in Liver Transplantation in Patients with HCC Diagnosis
*Purpose: Disparities in outcomes of hepatocellular carcinoma (HCC) have not been adequately studied, especially in the context of liver transplantation (LT). We sought to identify…2022 American Transplant Congress
Allocation Based on Acuity Circles Decreases Waiting Time for Liver Transplant Patients
Stanford University, Stanford, CA
*Purpose: In February, 2020, UNOS implemented a new liver allocation system incorporating a combination of acuity based on MELD/PELD score and distance from the donor…
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