2015 American Transplant Congress
Post-Liver Transplant Delirium Is Associated With Increased Mortality and Prolonged Length of Stay
Delirium after liver transplantation (LT) has been reported to increase ICU and hospital length of stay, but limited information is available regarding the incidence, potential…2015 American Transplant Congress
Patients With Spontaneous Bacterial Peritonitis (SBP) Experience Survival Benefit After Live Donor Liver Transplantation (LDLT)
Transplantation and Hepatobiliary Diseases, Lahey Hospital and Medical Center, Burlington, MA.
Background: SBP is a life threatening complication of end stage liver disease. Reports indicate a 40-50% one year mortality rate in patients who experience SBP…2015 American Transplant Congress
B7-H1 Deficiency in Liver Allografts Leads to CD8-Mediated Acute Vascular Rejection
The liver is a unique organ in that it is accepted across complete MHC mismatch in allotransplantation in a number of species. The mechanisms behind…2015 American Transplant Congress
Inside Out Autologous Neo-Liver Fabrication
Surgery, Stanford University School of Medicine, Stanford, CA.
Background: Creation of patient-specific replacement organs promises to address major shortcomings in transplantation. We previously described an approach to fabricate autologous, vascularized neo-organs by using…2015 American Transplant Congress
Impaired Autophagy: A Mechanism of Fatty Liver Increases Susceptibility to Ischemia Reperfusion Injury
BACKGROUND: Hepatic steatosis is associated with significant morbidity and mortality after transplantation. Autophagy was known as a protective response to ischemia and reperfusion (I/R) injury.…2015 American Transplant Congress
Interactions Between Platelets and Liver Sinusoidal Endothelial Cells Initiate Liver Regeneration
ObjectivesPlatelets and liver sinusoidal endothelial cells (LSEC) were shown to be important contributors to liver regeneration. Several recent studies suggested that their interactions might be…2015 American Transplant Congress
Hepatic Stellate Cells Directly Inhibit B Cells Via PD-L1
Hepatic stellate cells (HSCs) account for one third of the nonparenchymal cells in the liver, which are considered to be critical in maintaining the immunoprivileged…2015 American Transplant Congress
The Donor Risk Index Does Not Accurately Classify Patients With or Without Graft Failure
In liver transplantation assessing risk of donor is paramount to graft survival. The donor risk index (DRI) was introduced as a predictor of graft failure…
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