2015 American Transplant Congress
Down-Regulation of Autophagy Correlates With Increased Apoptosis in the Kidney, But Not in the Liver, of Brain Dead Rats
Organs from brain dead donors have inferior quality and show higher rejection rates after transplantation compared to living donors. Brain death (BD) in the donor…2015 American Transplant Congress
Increased Fibroblast Growth Factor 21 Levels in Biliary Atresia Patients
Renji Hospital, Shanghai, China.
Background: Fibroblast growth factor (FGF)-21, a hormone predominantly secreted by the liver, has recently been reported as a key circulating adipokine involving in metabolic disorders…2015 American Transplant Congress
Effect of Fully Laparoscopic Left Hepatectomy on Donor Interest in Living Donor Liver Transplantation (LDLT)
Purpose: Laparoscopy was extended to liver donation to reduce invasiveness and our center has offered selected patients fully laparoscopic procurement since 8/12. We sought to…2015 American Transplant Congress
Changing Demographics of HIV+ Liver Transplant Candidates
Liver transplant (LT) is considered a reasonable therapeutic option for certain HIV+ patients with end-stage liver disease (ESLD). As OPTN does not collect HIV status…2015 American Transplant Congress
Post-Liver Transplant Delirium Is Associated With Increased Mortality and Prolonged Length of Stay
Delirium after liver transplantation (LT) has been reported to increase ICU and hospital length of stay, but limited information is available regarding the incidence, potential…2015 American Transplant Congress
Patients With Spontaneous Bacterial Peritonitis (SBP) Experience Survival Benefit After Live Donor Liver Transplantation (LDLT)
Transplantation and Hepatobiliary Diseases, Lahey Hospital and Medical Center, Burlington, MA.
Background: SBP is a life threatening complication of end stage liver disease. Reports indicate a 40-50% one year mortality rate in patients who experience SBP…2015 American Transplant Congress
B7-H1 Deficiency in Liver Allografts Leads to CD8-Mediated Acute Vascular Rejection
The liver is a unique organ in that it is accepted across complete MHC mismatch in allotransplantation in a number of species. The mechanisms behind…2015 American Transplant Congress
Inside Out Autologous Neo-Liver Fabrication
Surgery, Stanford University School of Medicine, Stanford, CA.
Background: Creation of patient-specific replacement organs promises to address major shortcomings in transplantation. We previously described an approach to fabricate autologous, vascularized neo-organs by using…2015 American Transplant Congress
Impaired Autophagy: A Mechanism of Fatty Liver Increases Susceptibility to Ischemia Reperfusion Injury
BACKGROUND: Hepatic steatosis is associated with significant morbidity and mortality after transplantation. Autophagy was known as a protective response to ischemia and reperfusion (I/R) injury.…2015 American Transplant Congress
Interactions Between Platelets and Liver Sinusoidal Endothelial Cells Initiate Liver Regeneration
ObjectivesPlatelets and liver sinusoidal endothelial cells (LSEC) were shown to be important contributors to liver regeneration. Several recent studies suggested that their interactions might be…
American Transplant Congress abstracts