ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver"

  • 2016 American Transplant Congress

    Limited Hepatitis B Immune Globulin Following Liver Transplant for Hepatitis B.

    T. Sievers, J. Thompson, J. Lake.

    Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN.

    IntroductionThe hypothesis of this study was that the long-term outcomes in liver transplant (LTx) patients with hepatitis B virus (HBV) who were treated with nucleos(t)ide…
  • 2016 American Transplant Congress

    Outcomes of Small-for-Size Grafts in Adult Living Donor Liver Transplantation.

    T. Klair,1 E. Przybyszewski,1 B. Samstein.2

    1Columbia University Medical Center, New York; 2Weill Cornell Medical College, New York.

    Lower limit of graft size in adult Living donor liver transplantation (LDLT) is not well established. This study examines the outcomes with use of small-for-size…
  • 2016 American Transplant Congress

    Mesenchymal Stem Cells Reprogram Macrophage Polarization and Attenuate Liver Ischemia and Reperfusion Injury by Regulating Notch/Cox2/PGE2 Signaling Pathway.

    C. Li,1 S. Yue,1 R. Busuttil,1 J. Kupiec-Weglinski,1 B. Ke.1

    1The Dumont-UCLA Transplant Center, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA; 2Department of Physiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.

    Background and aims: Mesenchymal stem cells (MSCs) have been shown an immune modulatory properties and tissue repairing capability under inflammatory conditions. However, it is unknown…
  • 2016 American Transplant Congress

    The Medication Level Variability Index (MLVI), a Behavioral Biomarker, Predicts Late Allograft Rejection in Pediatric Liver Transplant Recipients – A Prospective Multisite Study.

    E. Shemesh,1 J. Bucuvalas,2 R. Anand,3 R. Venick,4 E. Alonso,5 J. Mitchell,3 R. Annunziato,1 G. Mazariegos,6 B. Shneider.7

    1Mount Sinai, New York; 2Children's Hospital, Cincinnati; 3Emmes Corporation, Rockville; 4UCLA, Los Angeles; 5Lurie Children's Hospital, Chicago; 6Children's Hospital, Pittsburgh; 7Children's Hospital, Texas.

    Objective: The MALT [Medication Adherence in children who had a Liver Transplant (LT), NCT-01154075, R01DK080740 (NIDDK)] multisite study prospectively evaluated a biomarker for erratic medication…
  • 2016 American Transplant Congress

    Barriers to the Wider Utilization of Living Donor Liver Transplantation (LDLT).

    A. Yegiants, E. Przybyszewski, A. Fox, J. Emond, B. Samstein.

    Center for Liver Disease and Transplantation, NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY.

    Purpose: LDLT reduces waitlist mortality, improves access to transplantation and has post-transplant outcomes that are equivalent to or better than deceased donor transplant. Despite these…
  • 2016 American Transplant Congress

    Anti-Inflammatory Effects of AAV-Mediated TIMP-1 Gene Transfer in Hepatic Ischemia-Reperfusion Injury.

    S. Duarte, T. Fujii, G. Lipshutz, R. Busuttil, A. Coito.

    The Dumont-UCLA Transplant Center, Los Angeles.

    Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase1 (TIMP-1) is the…
  • 2016 American Transplant Congress

    Utility of a Routine Bench Cholangiogram for Deceased Split Liver Procedure.

    N. Battula, R. Anbarasan, V. Thumma, K. Sharif, T. Perera, P. Muiesan, D. Mirza.

    Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; Liver Unit, Birmingham Children's Hospital, Birmingham, United Kingdom.

    Background: Biliary complications can result in a significant morbidity for split liver graft recipients. The segmental biliary anatomy, particularly the left biliary system is poorly…
  • 2016 American Transplant Congress

    Racial Disparities in Cognitive and Social Requirements Prior to Listing for Liver Transplant.

    M. Jesse, E. Goldstein, T. Macaulay, N. Rebhan, C.-X. Ho, M. Bebanic, L. Shkokani, M. Abouljoud, A. Eshelman, A. Yoshida.

    Transplant Institute, Henry Ford Health System, Detroit, MI.

    Guidelines for liver transplant candidates outline increased engagement of social supports in the context of patient cognitive impairments. However, there is little direction when limitations…
  • 2016 American Transplant Congress

    Activating Transcription Factor 5 (ATF5) Regulates Liver Ischemia/Reperfusion Injury.

    G.-Q. Shen,2 M. Morita,1 J. Fung,2 L. Lu,1,2 S. Qian.1,2

    1Immunology, LernerResearch Institute, Cleveland Clinic, Cleveland, OH; 2General Surgery, Transplant Center, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH.

    Activating transcription factor 5 (ATF5), a member of the ATF/cAMP response element-binding proteins, is extremely highly expressed in the liver, the significance of which is…
  • 2016 American Transplant Congress

    Impact of Proximity MELD/PELD Points on Liver Redistricting Scenarios.

    S. Gentry,1,2 J. Pyke,1 D. Schladt,1 J. Zeglin,1 W. Kim,3 J. Lake,4 R. Hirose,5 D. Mulligan,6 A. Israni.1

    1Scientific Registry of Transplant Recipients, Minneapolis; 2United States Naval Academy, Annapolis; 3Stanford, Palo Alto; 4University of Minnesota, Minneapolis; 5Surgery, University of California, San Francisco; 6Surgery, Yale University, New Haven.

    Background: To address geographic disparity in liver allocation, a new organ distribution system consisting of 4 or 8 districts has been proposed (Gentry, Am J…
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