Articles tagged "Liver"

2018 American Transplant Congress
Efficacy of Generic Sofosbuvir and Branded Daclatasvir Compared to Sofosbuvir and Ledipasvir Combination in the Treatment of Genotype 4 Hepatitis C Virus
H. Joharji, A. Al-Jedai, D. Alkortas, A. Ajlan, E. Devol, M. Ahmed, F. Aba Al-Khail, H. El-Siesy, M. Al-Sebayel, H. Al-Ashgar, M. Al-Quaiz, W. Alhomodi, A. Aloubal, A. Almohishir.
King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia.
Genotype 4 HCV is the most common genotype in Saudi Arabia and the Middle East. Management of genotype 4 HCV has shifted to interferon free…
2018 American Transplant Congress
Outcomes in Liver and Combined Liver-Kidney Retransplantation
D. Sonnier, D. Bruce, H. Bohorquez, E. Bugeaud, I. Carmody, A. Cohen, A. Mathur, J. Seal, G. Loss.
Department of Surgery/Transplantat, Ochsner Clinic, New Orleans, LA.
Many centers consider liver retransplantation controversial due to poor outcomes and high resource requirement. In the setting of renal failure and high MELD, many are…
2018 American Transplant Congress
Transplant Hepatectomy with Portacaval Shunt and Molecular Adsorbent Recirculating System (MARS) Therapy for Perioperative Catastrophe
A. Cimeno, S. Sultan, J. Alvarez-Casas, S. Hanish, D. Bruno, W. Hutson, D. Stein, T. Scalea, R. Barth, J. LaMattina.
University of Maryland School of Medicine, Baltimore, MD.
Background: Increased worldwide focus on maximal donor utilization and transplantation of patients once considered too ill to survive liver transplantation may increase the otherwise rare…
2018 American Transplant Congress
The Impact of Rapamycin Conversion in Pediatric Liver Transplantation on Anti-HLA Antibody Formation and Allograft Fibrosis
R. Fischer,² L. Fromm,¹ J. Daniel,² A. Kats,² R. Hendrickson,² W. Andrews.²
¹University of Kansas College of Medicine, Kansas City, KS; ²Children's Mercy Hospital, Kansas City, MO.
Background: Maintenance immunosuppression with tacrolimus (TAC) is associated with progressive liver allograft fibrosis. Conversion to rapamycin (RAPA) may abrogate this progression. The development of donor-specific…
2018 American Transplant Congress
Postoperative Renal Function Predicts Length of Stay for Incisional Hernia Repair after Liver Transplantation
J. Butler, D. O'Brien, J. Kays, C. Kubal, B. Ekser, J. Fridell, R. Mangus, J. Powelson.
Transplant Surgery, Indiana University, Indianapolis, IN.
Background: Incisional hernia repair (IHR) is the most frequently performed general surgery procedure after orthotopic liver transplantation (OLT). Although enhanced recovery protocols for general surgery…
2018 American Transplant Congress
Retransplantation after Living Donor Liver Transplantation: Analysis of Data from the A2ALL Study
H. Braun, J. Grab, J. Dodge, S. Syed, G. Roll, C. Freise, J. Roberts, N. Ascher.
Surgery, University of California, San Francisco, San Francisco, CA.
Living donor liver transplantation (LDLT) is associated with a higher incidence of post-transplant vascular and biliary complications. Outcomes for retransplantation (reLT) after LDLT are not…
2018 American Transplant Congress
Diffuse Optical Non-Invasive Organ Risk (DONOR) Indexing Using Diffuse Reflectance Spectroscopy for Pre-Transplant Evaluation
H. Borron,¹ D. Piao,² A. Hawxby,³ H. Wright,³ E. Rubin.⁴
¹College of Medicine, University of Oklahoma, Oklahoma City, OK; ²School of Electrical and Computer Engineering, Oklahoma State University, Stillwater, OK; ³Oklahoma Transplant Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK; ⁴Pathology, University of Oklahoma, Oklahoma City, OK.
Purpose: Due to large transplant waitlists, a rapid, non-invasive method to evaluate organ quality for transplantation is needed. Diffuse optical spectroscopy (DOSi) is an optical…
2018 American Transplant Congress
Role of Obesity in Pediatric Liver Transplantation
K. Covarrubias, M. Denhard, X. Luo, J. Garonzik-Wang, A. Cameron, D. Segev, D. Mogul.
JHU, Baltimore, MD.
PURPOSE: Pediatric obesity rates are climbing and the prevalence of obesity in children undergoing liver transplantation now exceeds that of the general population. Studies in…
2018 American Transplant Congress
Technical Aspects of Orthotopic Liver Transplantation – A Survey-Based Study within the Eurotransplant, Swisstransplant, Scandiatransplant and British Transplantation Society Networks
Z. Czigany,¹ J. Bednarsch,¹ J. Böcker,¹ F. Meister,¹ I. Amygdalos,¹ W. Schöning,¹ T. Ulmer,¹ X. Rogiers,² P. Dutkowski,³ P-.D. Line,⁴ M. Malagó,⁵ U. Neumann,¹ G. Lurje.¹
¹Department of Surgery and Transplantation, University Hospital RWTH, Aachen, Germany; ²Department of Solid Organ Transplantation, University Hospital Gent, Gent, Belgium; ³Department of Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland; ⁴Department of Solid Organ Transplantation, University Hospital Oslo, Oslo, Norway; ⁵Department of Hepatobiliary Surgery and Transplantation, University College London, London, United Kingdom.
Background: Surgical aspects of ortoptopic liver transplantation (OLT) are widely based on low-level evidence as well as on local institutional protocols. Aim of this study…
2018 American Transplant Congress
The Predictive Power of MELD is Decreasing in the Era of Older, Sicker Patients
E. Godfrey,¹ J. Lai,² T. Miloh,³ N. Galvan,¹ R. Cotton,¹ C. O'Mahony,¹ J. Vierling,¹ N. Sussman,¹ A. Rana.¹
¹Department of Surgery, Baylor College of Medicine, Houston, TX; ²Department of Medicine, University of California, San Francisco, San Francisco, CA; ³Department of Pediatrics, Baylor College of Medicine, Houston, TX.
PurposeThe field of liver transplantation has shifted considerably in the MELD era. Liver allocation, immunosuppression, and etiologies of liver failure have changed over time, and…