Articles tagged "Liver"

2021 American Transplant Congress
Early Hypertransaminasemia in Kidney Transplant Recipient: Influence of Donor Type and Clinical Significance
E. Solà-Porta, M. Redondo-Pachón, S. Núñez-Delgado, C. Arias-Cabrales, M. Mir, A. Buxeda, C. Burballa, M. Crespo, J. Pascual, M. Pérez-Sáez
Nephrology, Hospital del Mar, Barcelona, Spain
*Purpose: The increase in transaminases after kidney transplant (KT) is frequent. Although the cause is unknown, it has been associated with factors such as immunosuppression,…
2021 American Transplant Congress
When One Size Does Not Fit All: Geographically Heterogeneous Liver Distribution
M. A. Mankowski¹, S. Gentry², D. Segev³, N. Trichakis⁴
¹KAUST, Thuwal, Saudi Arabia, ²US Naval Academy, Annapolis, MD, ³JHU, Baltimore, MD, ⁴MIT, Boston, MA
*Purpose: The new liver allocation system prioritizes distribution within acuity circles, instead of within DSAs. Acuity circles have the same radius around all donor hospitals…
2021 American Transplant Congress
Influence of Frailty on Psychometric Factors and Health-related Quality of Life in Patients on the Waitlist for Liver Transplantation
C. G. Klein, J. Latuske, E. Malamutmann, A. Paul, A. Oezcelik
University Medicine Essen, Essen, Germany
*Purpose: The aim of this prospective study was to evaluate the influence of frailty on depression, anxiety and health-related quality of life for patients on…
2021 American Transplant Congress
Human Liver-derived Mesenchymal Stromal Cells (MSC) are Superior Inhibitors of Natural Killer Cells Compared to Bone Marrow or Adipose Tissue-derived MSC
F. Yigitbilek, M. J. Hansen, W. D. Park, M. D. Stegall, T. Taner
Mayo Clinic, Rochester, MN
*Purpose: Guided by the liver allografts’ unique tolerogenic microenvironment and the immunoprotective impact on simultaneously transplanted organs, we recently isolated liver mesenchymal stromal cells (L-MSC)…
2021 American Transplant Congress
Identification of Molecular Markers for Liver Cirrhosis by Single-nucleus Rna Sequencing
C. Kuscu¹, C. Kuscu¹, M. Akram², A. Shetty³, D. G. Maluf⁴, J. Eason¹, V. Mas⁵
¹Surgery, James D Eason Transplat Institute, Memphis, TN, ²Surgery, Center for Biomedical Informatics, Memphis, TN, ³Surgery, Institute for Genome Sciences, School of Medicine, Baltimore, MD, ⁴Surgery, Program in Transplantation University of Maryland, Baltimore, MD, ⁵Surgery, Division of Surgical Science University of Maryland, Baltimore, MD
*Purpose: Non-alcoholic fatty liver disease (NAFLD) is characterized by metabolic syndrome and the accumulation of fat in the liver cells (hepatocytes) leading to inflammation and…
2021 American Transplant Congress
Clearance of Viral RNA and DNA and Antibody Response Following Administration of Live Attenuated Measles and Varicella Vaccines in Children with Chronic Liver Disease
S. Kemme¹, A. Weinberg², A. G. Feldman¹
¹Children's Hospital Colorado, Denver, CO, ²University of Colorado Denver, Denver, CO
*Purpose: Guidelines recommend waiting four weeks between live vaccine administration and transplantation; however, there is little data to support this waiting period and it often…
2021 American Transplant Congress
Growing LDLT Volumes at a US Center- What Does It Take to Do Over 100 LDLTs Per Year
A. Humar, C. Hughes, G. Mazariegos, K. Soltys, A. Gallatin, K. Emmett, A. Tevar, M. Molinari, A. Ganoza, V. Gunabushanam, S. Ganesh
University of Pittsburgh, Pittsburgh, PA
*Purpose: LDLT remains underutilized in the US, accounting for
2021 American Transplant Congress
Microbial Signatures Promote Antibiotic-Mediated Alleviation of Peritransplant Liver Damage in Mouse Recipients
K. J. Dery¹, S. Kageyama¹, H. Hirao¹, H. Kojima¹, K. Kadono¹, T. Dong², J. W. Kupiec-Weglinski¹
¹The Dumont-UCLA Transplantation Center, Los Angeles, CA, ²Department of Medicine, Vatche & Tamar Manoukian Division of Digestive Diseases, UCLA, Los Angeles, CA
*Purpose: Although recent evidence shows that modifications of gut microbiota by antibiotics (Abx) influences liver allograft function, its compositional role in orthotopic liver transplantation (OLT)…
2021 American Transplant Congress
Longitudinal Quality of Life Assessment in Liver Transplant – Feasibility Study and Early Results
O. M. Siddiqui, P. Polineni, A. J. Thuluvath, C. Loftus
Northwestern University, Chicago, IL
*Purpose: In addition to survival, quality of life (QoL) is critical to optimizing care in liver transplantation (LT). Although QoL is associated with clinical outcomes…
2021 American Transplant Congress
Perivenular Fibrosis After Pediatric Liver Transplant
J. Lew, S. Cho, S. Feng, E. R. Perito
UCSF, San Francisco, CA
*Purpose: Graft fibrosis is a concerning long-term complication after pediatric liver transplant (LT) and though perivenular (PV) fibrosis is common, its likelihood of progression and…