Articles tagged "Liver"

2021 American Transplant Congress
Regional Trends in Liver Transplantation for Nonalcoholic Steatohepatitis
C. L. Hanlon¹, B. Saberi², L. Yuan¹
¹Internal Medicine, University of Southern California, Los Angeles, CA, ²Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Boston, MA
*Purpose: This study aims to evaluate regional trends in liver transplantation (LT) among adults in the United States (US) with nonalcoholic steatohepatitis (NASH), with particular…
2021 American Transplant Congress
Artificial Neural Network Application for MELDNa Prediction
L. Pruinelli¹, M. Nguyen¹, S. Olson¹, J. Zhou¹, J. Schold², T. Pruett¹, S. Ma¹, G. Simon¹
¹University of Minnesota, Minneapolis, MN, ²Cleveland Clinic Foundation, Cleveland, OH
*Purpose: The adoption of MELDNa decreased 90-days mortality on patients waiting for liver transplant (LT); however, there are no tools available to predict MELDNa trajectories…
2021 American Transplant Congress
The Pediatric National Liver Review Board: What Happens to Waitlist Registrations with Denied Exception Forms?
J. Foutz¹, C. Martinez¹, A. Henderson¹, E. K. Hsu², E. R. Perito³, J. Heimbach⁴
¹United Network for Organ Sharing, Richmond, VA, ²Seattle Children's Hospital, Seattle, WA, ³UCSF, San Francisco, CA, ⁴Mayo Clinic, Rochester, MN
*Purpose: On 5/14/19, the exceptions review process for pediatric liver transplant (LT) candidates was changed from 11 Regional Review Boards to one National Pediatric Liver…
2021 American Transplant Congress
MiRNA as Regulator of Cell Death and Inflammatory Response in Hepatic Iri
E. Bardhi¹, T. Rousselle¹, J. McDaniels¹, S. Bontha¹, J. Eason², D. Maluf¹, V. Mas³
¹Surgery, University of Maryland, Baltimore, MD, ²Surgery, James D Eason Transplant Institute, Memphis, TN, ³Surgery, University of Maryland - Division of Surgical Science, Baltimore, MD
*Purpose: Hepatic IRI represents a barrier to the use of available organs. Early graft dysfunction of donor livers is directly related to the severity of…
2021 American Transplant Congress
Given the Potential Impact on Liver Transplant Selection, Revisiting the Current Standard of Diagnosis of Hepatocellular Carcinoma
K. Amarell, B. Fisher, B. Park, K. Ko, B. Kallakury
Department of Pathology & Laboratory Medicine, Georgetown University School of Medicine, Washington, DC
*Purpose: The current standard of diagnosis of hepatocellular carcinoma (HCC) relies on non-invasive radiographic methods, namely computerized tomography (CT) and/or magnetic resonance imaging (MRI). However,…
2021 American Transplant Congress
Deep Learning Based Automatic Liver Volume Estimation and Segmentation via U-net Convolutional Neural Network
B. Marlatt¹, R. Pettit², J. Havelka¹, S. J. Corr³, A. Rana²
¹InformAI, Houston, TX, ²Baylor College of Medicine, Houston, TX, ³Houston Methodist, Houston, TX
*Purpose: To create a deep learning model to accurately perform abdominal organ segmentation and volumetric measurements on existing donor and recipient imaging for size matching.*Methods:…
2021 American Transplant Congress
Degree of T Cell Infiltration Predicts Treatment Response in Pediatric Liver Late Acute Cellular Rejection
M. Rogers, G. Begum, Q. Sun, A. Peters
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: Late acute cellular rejection (ACR) occurs >6mo post-liver transplant and is associated with chronic rejection and allograft loss. Currently, no diagnostic features predict ACR…
2021 American Transplant Congress
Spleen Tyrosine Kinase (syk): A Novel Regulator of Neutrophil Infiltration in Hepatic Iri
V. Boominathan, A. Kobayashi, S. Duarte, A. Zarrinpar
Surgery, University of Florida, Gainesville, FL
*Purpose: Hepatic ischemia-reperfusion injury (IRI) plays a governing role in orthotopic liver transplantation, significantly impairing early graft function and increasing organ susceptibility to rejection. Neutrophil…
2021 American Transplant Congress
Effects of TIPS on Transplant Outcomes for HCC
C. L. Hanlon¹, D. Toy¹, Y. Liu¹, S. Zhou¹, K. Zhou², J. Kahn², L. Yuan²
¹Internal Medicine, University of Southern California, Los Angeles, CA, ²Internal Medicine - Department of Gastroenterology and Hepatology, University of Southern California, Los Angeles, CA
*Purpose: The purpose of this study is to examine effects of TIPS placement on response to locoregional therapy (LRT) and clinical outcomes after liver transplantation…
2021 American Transplant Congress
Combined Liver and Lung Transplantation with Extended Normothermic Liver Preservation Using Transmedics Organ Care System (OCS)^TM Liver: A Single Center Experience
J. Konel¹, M. Shamaa², O. Shamaa², A. Elsabbagh², T. Kitajima², T. Ivanics², K. Delvecchio², A. Mohamed², S. Yeddula², K. Collins², A. Yoshida², M. Abouljoud², S. Nagai², M. Rizzari²
¹Wayne State University School of Medicine, Detroit, MI, ²Henry Ford Transplant Institute, Detroit, MI
*Purpose: Combined liver-lung transplantation (CLLT) is indicated in patients who cannot survive single-organ transplantation alone. Ex-situ normothermic machine perfusion (NMP) has been used to increase…