Articles tagged "Liver"

2021 American Transplant Congress
Identification of Molecular Markers for Liver Cirrhosis by Single-nucleus Rna Sequencing
C. Kuscu¹, C. Kuscu¹, M. Akram², A. Shetty³, D. G. Maluf⁴, J. Eason¹, V. Mas⁵
¹Surgery, James D Eason Transplat Institute, Memphis, TN, ²Surgery, Center for Biomedical Informatics, Memphis, TN, ³Surgery, Institute for Genome Sciences, School of Medicine, Baltimore, MD, ⁴Surgery, Program in Transplantation University of Maryland, Baltimore, MD, ⁵Surgery, Division of Surgical Science University of Maryland, Baltimore, MD
*Purpose: Non-alcoholic fatty liver disease (NAFLD) is characterized by metabolic syndrome and the accumulation of fat in the liver cells (hepatocytes) leading to inflammation and…
2021 American Transplant Congress
Clearance of Viral RNA and DNA and Antibody Response Following Administration of Live Attenuated Measles and Varicella Vaccines in Children with Chronic Liver Disease
S. Kemme¹, A. Weinberg², A. G. Feldman¹
¹Children's Hospital Colorado, Denver, CO, ²University of Colorado Denver, Denver, CO
*Purpose: Guidelines recommend waiting four weeks between live vaccine administration and transplantation; however, there is little data to support this waiting period and it often…
2021 American Transplant Congress
Growing LDLT Volumes at a US Center- What Does It Take to Do Over 100 LDLTs Per Year
A. Humar, C. Hughes, G. Mazariegos, K. Soltys, A. Gallatin, K. Emmett, A. Tevar, M. Molinari, A. Ganoza, V. Gunabushanam, S. Ganesh
University of Pittsburgh, Pittsburgh, PA
*Purpose: LDLT remains underutilized in the US, accounting for
2021 American Transplant Congress
Microbial Signatures Promote Antibiotic-Mediated Alleviation of Peritransplant Liver Damage in Mouse Recipients
K. J. Dery¹, S. Kageyama¹, H. Hirao¹, H. Kojima¹, K. Kadono¹, T. Dong², J. W. Kupiec-Weglinski¹
¹The Dumont-UCLA Transplantation Center, Los Angeles, CA, ²Department of Medicine, Vatche & Tamar Manoukian Division of Digestive Diseases, UCLA, Los Angeles, CA
*Purpose: Although recent evidence shows that modifications of gut microbiota by antibiotics (Abx) influences liver allograft function, its compositional role in orthotopic liver transplantation (OLT)…
2021 American Transplant Congress
Longitudinal Quality of Life Assessment in Liver Transplant – Feasibility Study and Early Results
O. M. Siddiqui, P. Polineni, A. J. Thuluvath, C. Loftus
Northwestern University, Chicago, IL
*Purpose: In addition to survival, quality of life (QoL) is critical to optimizing care in liver transplantation (LT). Although QoL is associated with clinical outcomes…
2021 American Transplant Congress
Perivenular Fibrosis After Pediatric Liver Transplant
J. Lew, S. Cho, S. Feng, E. R. Perito
UCSF, San Francisco, CA
*Purpose: Graft fibrosis is a concerning long-term complication after pediatric liver transplant (LT) and though perivenular (PV) fibrosis is common, its likelihood of progression and…
2021 American Transplant Congress
Coronary Computed Tomography Angiography for Pre-Liver Transplant Cardiovascular Risk Assessment: A Single Center Experience
J. Rice¹, T. Genders², D. Groves², J. R. Burton¹, J. Moloo², R. Quaife², D. Vargas³, M. Kriss¹
¹Division of Gastroenterology and Hepatology, University of Colorado, Aurora, CO, ²Division of Cardiology, University of Colorado, Aurora, CO, ³Division of Radiology, University of Colorado, Aurora, CO
*Purpose: Coronary computed tomography angiography (CCTA) is an established non-invasive imaging modality for diagnosing coronary artery disease (CAD), though its use for cardiovascular disease (CVD)…
2021 American Transplant Congress
Galectin-3 Levels in Pediatric Cholestatic Liver Disease
D. Yoeli¹, Z. Wang¹, Y. Luo², A. Chaidez², M. A. Adams¹, C. A. Huang¹, C. L. Mack², N. Navarro Alvarez¹
¹Transplant Surgery, University of Colorado, Aurora, CO, ²Pediatric Gastroenterology, Hepatology and Nutrition, Children’s Hospital Colorado, Aurora, CO
*Purpose: Biliary atresia (BA) and other cholestatic liver diseases (CLD) are the most common indications for liver transplantation in children. Research on galectin-3, a protein…
2021 American Transplant Congress
Varicella Hepatitis Mimicking Immune Checkpoint Inhibitor-induced Liver Toxicity
M. J. Weiss¹, X. Zhang², E. K. Spengler¹
¹Gastroenterology and Hepatology, University of Wisconsin, Madison, WI, ²Pathology, University of Wisconsin, Madison, WI
*Purpose: Nivolumab is an anti-PD-1 monoclonal antibody belonging to a class of immune checkpoint inhibitors (ICI) used for many malignancies. A major limitation to their…
2021 American Transplant Congress
Intestinal Insufficiency May Affect Outcomes After Pediatric Liver Transplantation
A. K. Batra, M. Desai, J. Yang, K. Cummins, H. Oden-Brunson, H. Ling, S. Beer, J. Goss, N. Galvan
Surgery, Baylor College of Medicine, Houston, TX
*Purpose: The purpose of this study is to determine if pre-transplant feeding intolerance is associated with poorer post-OLT (orthotopic liver transplant) outcomes in pediatric liver…