Articles tagged "Liver transplantation"

2018 American Transplant Congress
Dual Function of IRF1/IRF4 on Dendritic Cells in Mouse Liver Transplantation Model
G. Gu, T. Lu, N. Xu, Q. Xia.
Department of Liver Surgery, Renji Hospital, Affiliated by Shanghai Jiaotong University School of Medicine, Shanghai, China.
Tolerogenic dendritic cells play an essential role in transplant tolerance induction. However, how to induce tolerogenic dendritic cells is not fully understood. Here, we sorted…
2018 American Transplant Congress
Clinical Impact of Antecedent Bariatric Surgery on Liver Transplant Outcomes: A Retrospective Matched Case-Control Study
O. Serrano,¹ K. Peterson,¹ D. Vock,² D. Berglund,¹ R. Kandaswamy,¹ J. Lake,³ T. Pruett,¹ S. Chinnakotla.¹
¹Surgery, University of Minnesota, Minneapolis, MN; ²Biostatistics, University of Minnesota, Minneapolis, MN; ³Medicine, University of Minnesota, Minneapolis, MN.
OBJECTIVE: Bariatric surgery (BS) is associated with significant malabsorption and nutritional deficiencies, which can have profound consequences on the liver transplant (LT) patient. The magnitude…
2018 American Transplant Congress
National Landscape of HIV+ Liver Transplant Candidates
A. Shaffer,¹ A. Thomas,¹ A. Massie,¹ S. Gustafson,² J. Snyder,² B. Shelton,³ R. Reed,³ J. Locke,³ D. Segev,¹ C. Durand.¹
¹JHU, Baltimore; ²SRTR, Minneapolis; ³UAB, Birmingham.
The annual number of HIV+ liver transplant (LT) recipients has increased >10-fold since 2002. However, candidate HIV-status is not collected by UNOS, and the national…
2018 American Transplant Congress
Graft CEACAM1 is Essential to Autophagy Induction and T-Cell Regulation in Liver Transplantation: From Mouse-to-Human
K. Nakamura,¹ S. Kageyama,¹ M. Kujawski,² T. Ito,¹ A. Aziz,¹ D. Oncel,¹ B. Ke,¹ R. Sossa,³ E. Reed,³ F. Kaldas,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Liver Transplant, UCLA, Los Angeles, CA; ²Molecular Immunology, City of Hope, Duarte, CA; ³Pathology, UCLA, Los Angeles, CA.
We have documented crucial role of TIM-3 dependent T cell dysfunction in mouse orthotopic liver transplantation (OLT). CEACAM1 (CM1; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1),…
2018 American Transplant Congress
Transplantation of DCD Livers vs. NDD and LDLT: Is There a Difference in Post-Transplant Kidney Dysfunction?
D. Kollmann,¹ S. Neong,¹ R. Rosales,¹ G. Sapisochin,¹ M. Bhat,¹ M. Cattral,¹ P. Greig,¹ L. Lilly,¹ D. McGilvray,¹ A. Ghanekar,¹ D. Grant,¹ M. Selzner,¹ F. Wong,² N. Selzner.¹
¹Multi Organ Transplant, Toronto General Hospital, Toronto, Canada; ²Division of Gastroenterology, Toronto General Hospital, Toronto, Canada.
Background. Recipients of donation after circulatory death (DCD) grafts are reportedly at higher risk of developing post liver transplant (LT) renal dysfunction. Our aim was…
2018 American Transplant Congress
Single-Center Experience of Biliary Reconstruction for Multiple Bile Duct in Right Lobe Living Donor Liver Transplantation
J-.D. Kim, D-.L. Choi, T. Kim.
Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea.
Biliary anastomosis stricture (BAS) is still major concerns especially for living donor liver transplantation (LDLT). Recent studies have described multiple duct and multiple anastomoses as…
2018 American Transplant Congress
Sequential Percutaneous Insertion of Two Plastic Biliary Stents through One Percutaneous Access for Biliary Anastomotic Strictures after Liver Transplantation
F. Boyvat,¹ A. Harman,¹ A. Akdur,² C. Aytekin,¹ M. Kirnap,² G. Moray,² M. Haberal.²
¹Radiology, Baskent University, Ankara, Turkey; ²Transplantation, Baskent University, Ankara, Turkey.
Introduction: Our purpose was to evaluate the management of biliary anastomotic strictures with simultaneous multiple percutaneous plastic stents for liver transplantsMaterials and Methods: Between 2007…
2018 American Transplant Congress
Potential Living Donors Identified through Social Media
S. Weeks, K. Kumar, J. Konel, E. King, M. Henderson, A. Cameron, J. Garonzik Wang.
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD.
Purpose: We previously described a smartphone application that harnesses social media to increase potential living donors among kidney and liver transplant candidates. We compared potential…
2018 American Transplant Congress
SIRT1-Ikaros Axis Promotes Macrophage M2 Polarization and Protects Liver Graft from Ischemia-Reperfusion Injury
K. Nakamura,¹ S. Kageyama,¹ X. Li,² A. Aziz,¹ R. Sosa,³ E. Reed,³ F. Kaldas,¹ R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Liver Transplant, UCLA, Los Angeles, CA; ²NIEHS, Durham, NC; ³Pathology, UCLA, Los Angeles, CA.
Although pre-clinical studies have reported the efficacy of Sirtuin 1 (SIRT1) to protect livers from ischemia-reperfusion injury, its clinical relevance in liver transplantation (LT) has…
2018 American Transplant Congress
Private Insurance is Associated with Reduce Access to HCV Therapy after Liver Transplantation
D. Axelrod,¹ M. Schnitzler,² B. Kasiske,³ G. Hess,⁴ R. Bloom,⁵ F. Gordon,¹ H. Randall,² K. Lentine.²
¹Lahey Clinic, Burlington; ²Saint Louis U, St. Louis; ³SRTR, Minneapolis; ⁴Symphony Health, Conshohocken; ⁵U Penn, Philadelphia.
Effective treatment for hepatitis C virus (HCV) infection has revolutionized post liver transplant (LTx) care. Administration of direct-acting antiviral agents (DAAs) after HCV+ LTx results…