Articles tagged "Liver transplantation"

2018 American Transplant Congress
Factors Predicting Viability Achievement on Discarded Donor Livers Submitted to Extra-Corporeal Machine Perfusion
Y. Boteon,^1,2 R. Laing,^1,2 A. Schlegel,² J. Attard,^1,2 L. Wallace,¹ A. Smith,² T. Perera,² J. Isaac,² D. Mirza,² S. Afford,¹ H. Mergental.²
¹National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; ²Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.
Background: Ex-vivo machine perfusion of livers (MP) may offer superior preservation for marginal donor organs. During normothermic machine perfusion (NMP) is possible to assess liver…
2018 American Transplant Congress
Clinical Analysis of Impact of Intraoperative Hepatic Blood Inflow on Acute Kidney Injury Following Allogeneic Liver Transplantation
J. Zhang, Q. Liu, X. Li, Y. Meng, L. Yang, C. Zhang, N. Sun, A. Jiao, J. Lin.
Hepatobiliary Surgery Department and Unit of Organ Transplantation, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Background Acute kidney injury (AKI) is a major and severe complication following allogeneic liver transplantation and is associated with increased postoperative morbidity and mortality. With…
2018 American Transplant Congress
Impact of Donor Age on Outcomes after Living Donor Liver Transplantation
K. Hayashi,¹ K. Gotoh,¹ H. Eguchi,¹ Y. Iwagami,¹ D. Yamada,¹ T. Asaoka,¹ T. Noda,¹ K. Kawamoto,¹ S. Kobayashi,¹ K. Umeshita,² Y. Doki,¹ M. Mori.¹
¹Dept of Gastroenterological Sugery, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan; ²Division of Health Science, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
Background: Liver transplantation (LT) is a curative treatment for decompensated cirrhosis and fulminant hepatitis. Although not a few patients received LT with marginal donor livers…
2018 American Transplant Congress
Livers from Diabetic Donors Can Safely Be Used in Donation after Circulatory Death Liver Transplantation
I. Brüggenwirth,¹ I. Vasiliauskaire,² A. Westerkamp,¹ W. Polak,² A. Braat,³ R. Porte.¹
¹Surgery, UMCG, Groningen, Netherlands; ²Surgery, Erasmus MC, Rotterdam, Netherlands; ³Surgery, LUMC, Leiden, Netherlands.
Liver grafts from donors with a history of diabetes mellitus (DM) have been associated with reduced graft survival after liver transplantation. Transplantation centers are often…
2018 American Transplant Congress
Safety of Antithymocyte Globulin Use in Donation after Circulatory Death (DCD) Liver Transplantation
D. Felix,¹ B. Geiger,¹ J. Descourouez,¹ M. Jorgenson,¹ B. Hanlon,² G. Leverson,² D. Foley.²
¹Department of Pharmacy, UW Health, Madison, WI; ²Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Purpose: Rabbit antithymocyte globulin (rATG) is commonly used for induction immunosuppression and treatment of rejection in solid organ transplantation. Previous work has shown that rATG…
2018 American Transplant Congress
The First Series of Ischemia-Free Liver Transplantation in Human
X. He,¹ Z. Guo,¹ S. Huang,¹ Q. Zhao,¹ Y. Tang,¹ Z. Zhang,¹ Z. Zhu,¹ W. Ju,¹ L. Yang,² G. Chen.¹
¹Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; ²Department of Anesthesiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
BACKGROUND&AIMS: Ischemia and reperfusion injury (IRI) is known as an inevitable event leading to early and late graft failure. We have performed the first case…
2018 American Transplant Congress
Making Sense of Hepatitis B Reactivation Risk in Anti-HBc Antibody (Ab) Positive Liver Transplant Recipients
S. Leistman,¹ J. Melaragno,¹ M. Dokus,² B. Al-Judaibi,² T. Babu.³
¹Department of Pharmacy, University of Rochester Medical Center, Rochester, NY; ²Division of Transplantation, University of Rochester Medical Center, Rochester, NY; ³Division of Infectious Diseases, University of Rochester Medical Center, Rochester, NY.
Background: Limited data exists regarding the rates of reactivation of hepatitis B virus (HBV) in anti-HBc Ab positive orthotopic liver transplant (OLT) recipients. Protocols vary…
2018 American Transplant Congress
Donor Liver Apoptosis is Associated with Early Allograft Dysfunction and Short-Time Graft Survival after Liver Transplantation
Z. Guo, Z. Zhu, Y. Tang, S. Huang, Z. Zhang, X. He, G. Chen.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Aims The aim of the study was to determine whether donor liver apoptosis is predictive for early allograft dysfunction (EAD) and graft survival after liver…
2018 American Transplant Congress
Effect of HLA Antibodies on Graft Survival in Adult Live Donor Liver Transplantation
M. Simpson,¹ M. Akoad,¹ F. Gordon,¹ Y-.L. Cheah,¹ C. Simon,¹ J. Pomposelli,² E. Pomfret.²
¹Transplantation, Lahey Hospital & Medical Center, Burlington, MA; ²Transplantation, University of Colorado Medical Center, Aurora, CO.
The relevance of HLA antibodies in liver transplantation is currently being re-evaluated. While hyperacute rejections are not an issue, antibody effects on long-term outcomes are…
2018 American Transplant Congress
Liver Retransplantation and Renal Failure: The Benefit of Simultaneous Kidney Transplant
J. Berumen,¹ V. Irine,² S. Mita,² S. Gabriel,¹ M. Kristin.¹
¹Department of Surgery, University of California San Diego, San Diego, CA; ²Department of Medicine, University of California San Diego, San Diego, CA.
Liver retransplantation has poor survival compared to primary liver transplant. Renal failure is a proven negative risk factor for survival with retransplant. Our aim was…