Articles tagged "Liver transplantation"

2018 American Transplant Congress
Small-for-Size Grafts Increase Recurrence of Hepatocellular Carcinoma in Liver Transplantation beyond Milan Criteria
E. Lee, S. Kim, J. Shim, J. Park, B. Na, S-.J. Park.
Center for Liver Cancer, National Cancer Center, Goyang, Korea.
BACKGROUND: Living donor liver transplantation (LDLT) has been reported to have high rates of hepatocellular carcinoma (HCC) recurrence compared to deceased donor liver transplant (DDLT).…
2018 American Transplant Congress
Technical Aspects of Orthotopic Liver Transplantation – A Survey-Based Study within the Eurotransplant, Swisstransplant, Scandiatransplant and British Transplantation Society Networks
Z. Czigany,¹ J. Bednarsch,¹ J. Böcker,¹ F. Meister,¹ I. Amygdalos,¹ W. Schöning,¹ T. Ulmer,¹ X. Rogiers,² P. Dutkowski,³ P-.D. Line,⁴ M. Malagó,⁵ U. Neumann,¹ G. Lurje.¹
¹Department of Surgery and Transplantation, University Hospital RWTH, Aachen, Germany; ²Department of Solid Organ Transplantation, University Hospital Gent, Gent, Belgium; ³Department of Surgery and Transplantation, University Hospital Zurich, Zurich, Switzerland; ⁴Department of Solid Organ Transplantation, University Hospital Oslo, Oslo, Norway; ⁵Department of Hepatobiliary Surgery and Transplantation, University College London, London, United Kingdom.
Background: Surgical aspects of ortoptopic liver transplantation (OLT) are widely based on low-level evidence as well as on local institutional protocols. Aim of this study…
2018 American Transplant Congress
Impact of Local Liver Supply on Liver Offer Acceptance
M. Bowring,¹ S. Zhou,¹ A. Massie,¹ S. Gentry,^1,2 D. Segev.¹
¹JHU, Baltimore; ²US Naval Academy, Annapolis.
Geographic disparity in access to deceased-donor liver transplantation is well described. The available liver supply in a DSA may affect patient and provider decisions on…
2018 American Transplant Congress
Impact of Direct Acting Antiviral Agents (DAAs) for Hepatitis C Virus (HCV)-Induced Liver Diseases on Registration and Outcome on Waiting List (WL) for Liver Transplant (LT)
C. Antoine,¹ C. Jasseron,¹ F. Conti,² S. Dharancy,³ C. Duvoux,⁴ A. Coilly.⁵
¹Medical and Scientific Department, Agence de la Biomedecine, Agence de la Biomedecine, La Plaine Saint Denis, Saint Denis, France; ²Department of Hepatology, University Hospital La Pitie, Paris, France; ³Department of Hepatology, University Hospital Huriez, Lille, Nord Pas de Calais, France; ⁴Department of Hepatology, University Hospital Henri Mondor, Créteil, Val de Marne, France; ⁵Department of Hepatology, University Hospital Paul Brousse, Villejuif, Val de Marne, France.
2d-generation DAAs have dramatically improved the management of patients with HCV, including patients with advanced diseases. In France, since 2013, DAA have been largely used,…
2018 American Transplant Congress
T Cell Exhaustion Contributes to Operational Tolerance of Liver Allografts in Pediatric Liver Transplant Recipients
B. Ramaswami,¹ M. Marrari,² O. Yoshida,⁵ X. Guo,³ W. Hoffman,³ C. Bentlejewski,² D. Metes,¹ A. Demetris,^1,2 A. Zeevi,² A. Thomson,¹ G. Mazariegos,⁴ G. Chalasani.^1,3
¹Surgery, Starzl Transplantation Institute, Pittsburgh, PA; ²Pathology, University of Pittsburgh, Pittsburgh, PA; ³Medicine, University of Pittsburgh, Pittsburgh, PA; ⁴Children's Hospital, University of Pittsburgh, Pittsburgh, PA; ⁵Gastroenterology, Ehime University Graduate School of Medicine, Toon-shi, Ehime-ken, Japan.
Operational tolerance in the absence of immunosuppression can be successfully attained in pediatric liver transplant recipients. Although DSA are observed in a proportion of operationally…
2018 American Transplant Congress
Influence of Initial Tumor Burden and Wait Times on Post-Transplant Outcomes after Down-Staging of Hepatocellular Carcinoma (HCC)
N. Mehta, J. Dodge, F. Yao.
UCSF, San Francisco.
Background: A new national policy has adopted the UNOS Region 5 down-staging protocol for liver transplant (LT) in HCC meeting the following inclusion criteria -…
2018 American Transplant Congress
The Use of LiMAx for Evaluating Donor Livers on Normothermic Machine Perfusion
J. Schurink,¹ J. de Haan,² M. Verstegen,¹ H. Metselaar,³ J. Ijzermans,¹ J. de Jonge.¹
¹Surgery, Erasmus MC, Rotterdam, Zuid Holland, Netherlands; ²Intensive Care Medicine, Erasmus MC, Rotterdam, Zuid Holland, Netherlands; ³Gastroenterology, Erasmus MC, Rotterdam, Zuid Holland, Netherlands.
Due to the organ shortage, inferior quality livers from donors after circulatory arrest (DCD) are offered to relieve mortality on the waiting list. The threshold…
2018 American Transplant Congress
The Utility and Futility of Extra-Corporeal Membrane Oxygenation in Liver Transplant Recipients
B. Nguyen, K. Dhanireddy, Y. Genyk, N. Kaur.
University of Southern California, Los Angeles, CA.
Extra-corporeal membrane oxygenation (ECMO) is a therapeutic modality used to treat refractory hypoxemia, and help support cardiogenic shock. These conditions are seen in liver transplant…
2018 American Transplant Congress
Predicting Liver Allograft Discard: The Discard Risk Index
A. Rana, M. Kueht, N. Galvan, R. Cotton, T. Miloh, C. O'Mahony, J. Goss.
Abdominal Transplantation, Baylor College of Medicine, Houston, TX.
Background: An index that predicts liver allograft discard can effectively grade allografts and can be used to preferentially allocate marginal allografts to aggressive centers. Aim:…
2018 American Transplant Congress
Racial Disparities in Post-Liver Transplant Survival before and after Share 35 Implementation
K. Ross,¹ R. Lynch,² R. Patzer.^1,2
¹Department of Epidemiology, Rollins School of Public Health, Atlanta, GA; ²Emory Transplant Center, Atlanta, GA.
Background: The Share 35 policy was intended to improve equity in access to liver transplantation by broadening regional sharing of livers for the sickest patients…