ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2019 American Transplant Congress

    QA of MMR/VZV Protocol-Driven Serologic Screening and Infectious Disease Consultation (IDC) Are Strongly Recommended in Heart, Lung, Liver (HLL) SOTs

    Z. Seckin, L. Brumble, C. Libertin

    Mayo Clinic, Jacksonville, FL

    *Purpose: SOT recipients are at risk of acquiring life-threatening infections putting their graft and life at risk. Prevention, including immunization with live virus vaccines pre-transplantation…
  • 2019 American Transplant Congress

    Assessing the Effectiveness of Early Maintenance Immunosuppression Practices in Liver Transplantation

    T. Bittermann, R. Hubbard, J. Lewis, D. Goldberg

    University of Pennsylvania, Philadelphia, PA

    *Purpose: Evidence regarding the efficacy of maintenance immunosuppression (IS) regimens for liver transplantation (LT) arise from clinical trials. However, the ‘real world’ effectiveness of such…
  • 2019 American Transplant Congress

    Assessing Discarded Human Liver Quality with Normothermic Ex-Vivo Liver Perfusion

    F. Zhou, M. Xu, S. Garcia-Aroz, G. A. Upadhya, Y. Lin, W. C. Chapman

    Surgery, Washington University in St. Louis, St. Louis, MO

    *Purpose: Normothermic Ex-vivo Liver Perfusion (NELP) of livers shows promising results in overcoming injuries that occur in deceased donor liver transplantation. The effect of NELP…
  • 2019 American Transplant Congress

    Development and Validation of a Capillary Blood Mitra-Based Assay for the Quantitative Determination of Advagraf® Concentrations in Transplant Patients

    N. Undre1, I. Dawson2, V. Aluvihare3, N. Kamar4, F. Saliba5, N. Torpey6, S. Anaokar7, G. Kazeem1

    1Astellas Pharma Europe Ltd, Chertsey, United Kingdom, 2Covance Laboratories, Harrogate, United Kingdom, 3Kings College Hospital, London, United Kingdom, 4CHU Rangueil, Toulouse, France, 5Hôpital Paul-Brousse, Villejuif, France, 6Addenbrookes Hospital, Cambridge, United Kingdom, 7Astellas Pharma Europe Ltd, Surrey, United Kingdom

    *Purpose: Therapeutic drug monitoring of tacrolimus (TAC) requires venepuncture blood samples taken by specialists, requiring patients to attend an outpatient clinic; this can be inconvenient…
  • 2018 American Transplant Congress

    Assessment of a Discharge Transplant Knowledge Quiz and Its Impact on Outcomes in Liver Transplant Recipients

    H. Corbo, N. Patel, N. Pilch, C. Perez, J. Fleming, T. Harrison, J. Hardcopf, H. Meadows, B. O'Brien, J. McGillicuddy, P. Baliga, D. Taber.

    Medical University of South Carolina, Charleston, SC.

    The aim of this study is to determine if transplant quiz scores given prior to discharge were predictive of known patient risk factors and if…
  • 2018 American Transplant Congress

    Recombinant Relaxin Protects Liver Transplants from Ischemia-Reperfusion Damage via Hepatocyte Glucocorticoid Receptor: From Bench-to-Bedside

    S. Kageyama,1 K. Nakamura,1 T. Ito,1 A. Aziz,1 B. Ke,1 R. Sossa,2 E. Reed,2 F. Kaldas,1 R. Busuttil,1 J. Kupiec-Weglinski.1

    1Surgery, Division of Liver Transplantation, UCLA, Los Angeles, CA; 2Pathology, UCLA, Los Angeles, CA.

    Hepatic ischemia-reperfusion injury (IRI) represents a major risk factor of early graft dysfunction and acute/chronic rejection as well as a key obstacle to expanding the…
  • 2018 American Transplant Congress

    Incidence of Acute Cellular Rejection in Liver Transplant Patients Receiving Direct Acting Antivirals for Hepatitis C Treatment

    D. Bley,1 L. Sagardia,1 R. Ford,2 S. Todd.1

    1Pharmacy, Emory University Hospital, Atlanta, GA; 2School of Medicine, Emory University, Atlanta, GA.

    Direct acting antivirals (DAAs) have been used for the treatment of hepatitis C (HCV) in liver transplant patients since early on after their approval, however…
  • 2018 American Transplant Congress

    Living Liver Donor Follow-Up: Fewer Than Half of Centers Meet Follow-Up Requirements in the US

    A. Thomas, C. Holscher, A. Shaffer, J. Garonzik-Wang, A. Massie, D. Segev, M. Henderson.

    JHU, Baltimore.

    OPTN/UNOS began requiring 1-year living donor follow-up (LDF) for living liver donors (LLDs) in 2014. Compliance with a similar policy for living kidney donors was…
  • 2018 American Transplant Congress

    The Feasibility of Laparoscopic Living Donor Right Hepatectomy Compared to Open Surgery Including 100 Laparoscopic Cases

    J. Rhu, G. Choi, J. Kim, J. Joh, C. Kwon, S. Kim.

    Department of Surgery, Samsung Medical Center, Seoul, Republic of Korea.

    Background: We designed this study to analyze the feasibility of laparoscopic living donor hepatectomy by comparing to open living donor hepatectomy.Methods : Living donors who…
  • 2018 American Transplant Congress

    Histone Deacetylase-6 Inhibition Mitigates Liver Ischemia-Reperfusion Injury and Acetaminophen Toxicity in Mice

    S. Concors,1 D. Murken,1 D. Aufhauser,1 Z. Wang,1 G. Ge,1 T. Bhatti,4 W. Hancock,3,4 M. Levine.1,2

    1Surgery, University of Pennsylvania, Philadelphia, PA; 2Surgery, Children's Hospital of Philadelphia, Philadelphia, PA; 3Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; 4Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

    Introduction: Ischemia/reperfusion injury (IRI) leads to poor outcomes and early graft loss in liver transplantation. Understanding the mechanisms of liver IRI may aid in prevention…
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