Articles tagged "Liver transplantation"

2019 American Transplant Congress
Management of Dyslipidemia after Liver Transplantation
S. S. Patel¹, V. A. Rodriguez², M. B. Siddiqui¹, M. Faridnia³, F. Lin⁴, J. Laurenzano⁴, J. Clinton⁴, A. Chandrakumaran³, T. Reichman⁵, C. Bhati⁵, M. S. Siddiqui¹
¹Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, ²Department of Bio-statistics, Virginia Commonwealth University, Richmond, VA, ³Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, ⁴Virginia Commonwealth University, Richmond, VA, ⁵Department of Transplant Surgery, Virginia Commonwealth University, Richmond, VA
*Purpose: Cardiovascular disease (CVD) remains a major cause of long-term mortality in liver transplant recipients (LTR). Adequate control of CVD risk factors like hypertension, diabetes,…
2019 American Transplant Congress
Novel Cell-Free and Concentrated Ascites Reinfusion Therapy for Management of Refractory Ascites in Liver Transplant Candidates
K. Sato, M. Ohira, Y. Imaoka, S. Hashinoto, H. Tahara, K. Ide, T. Kobayashi, Y. Tanaka, H. Ohdan
Department of Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan
*Purpose: Refractory ascites at perioperative period in liver transplantation (LT) is associated with the increased morbidity and mortality. The aim of this study is to…
2019 American Transplant Congress
Geographic Disparities in Liver Supply/Demand Ratio within Fixed-Distance and Fixed-Person Circles
C. Haugen¹, T. Ishaque¹, A. Sapirstein¹, D. Segev¹, S. Gentry²
¹JHU, Baltimore, MD, ²USNA, Baltimore, MD
*Purpose: Geographic disparity in deceased donor liver allocation has been extensively documented. Many stakeholders believe allocating within circular fixed-distance or fixed-person boundaries would reduce geographic…
2019 American Transplant Congress
Repeat Liver Transplantation after Failed First Transplant in Childhood: Development of a Retransplant Risk Index
M. Gupta¹, M. Barry², M. Levine³, K. Olthoff³, A. Shaked³, P. Abt³
¹University of Kentucky, Lexington, KY, ²University of California, San Francisco, San Francisco, CA, ³University of Pennsylvania, Philadelphia, PA
*Purpose: Most morbidity and mortality after pediatric liver retransplantation (LRTx) occurs in the first 100 days. We studied factors associated with mortality and graft failure…
2019 American Transplant Congress
QA of MMR/VZV Protocol-Driven Serologic Screening and Infectious Disease Consultation (IDC) Are Strongly Recommended in Heart, Lung, Liver (HLL) SOTs
Z. Seckin, L. Brumble, C. Libertin
Mayo Clinic, Jacksonville, FL
*Purpose: SOT recipients are at risk of acquiring life-threatening infections putting their graft and life at risk. Prevention, including immunization with live virus vaccines pre-transplantation…
2019 American Transplant Congress
Assessing the Effectiveness of Early Maintenance Immunosuppression Practices in Liver Transplantation
T. Bittermann, R. Hubbard, J. Lewis, D. Goldberg
University of Pennsylvania, Philadelphia, PA
*Purpose: Evidence regarding the efficacy of maintenance immunosuppression (IS) regimens for liver transplantation (LT) arise from clinical trials. However, the ‘real world’ effectiveness of such…
2019 American Transplant Congress
Assessing Discarded Human Liver Quality with Normothermic Ex-Vivo Liver Perfusion
F. Zhou, M. Xu, S. Garcia-Aroz, G. A. Upadhya, Y. Lin, W. C. Chapman
Surgery, Washington University in St. Louis, St. Louis, MO
*Purpose: Normothermic Ex-vivo Liver Perfusion (NELP) of livers shows promising results in overcoming injuries that occur in deceased donor liver transplantation. The effect of NELP…
2019 American Transplant Congress
Development and Validation of a Capillary Blood Mitra-Based Assay for the Quantitative Determination of Advagraf® Concentrations in Transplant Patients
N. Undre¹, I. Dawson², V. Aluvihare³, N. Kamar⁴, F. Saliba⁵, N. Torpey⁶, S. Anaokar⁷, G. Kazeem¹
¹Astellas Pharma Europe Ltd, Chertsey, United Kingdom, ²Covance Laboratories, Harrogate, United Kingdom, ³Kings College Hospital, London, United Kingdom, ⁴CHU Rangueil, Toulouse, France, ⁵Hôpital Paul-Brousse, Villejuif, France, ⁶Addenbrookes Hospital, Cambridge, United Kingdom, ⁷Astellas Pharma Europe Ltd, Surrey, United Kingdom
*Purpose: Therapeutic drug monitoring of tacrolimus (TAC) requires venepuncture blood samples taken by specialists, requiring patients to attend an outpatient clinic; this can be inconvenient…
2019 American Transplant Congress
Results of Litmus (nct 02541916): The Liver Immune Tolerance Bio Marker Utilization Study
A. Chruscinski¹, V. Rojas-Luengas¹, S. Moshkelgosha¹, J. Luo², H. Yowanto², Z. Galvin¹, L. Lilly¹, R. Smith¹, E. Renner¹, J. Zhang¹, D. Grant¹, O. Adeyi¹, H. Atkins³, P. Juni⁴, N. Selzner¹, S. Juvet¹, G. Levy¹
¹Multi-Organ Transplantation, University Health Network, Toronto, ON, Canada, ²Sciex, Brea, CA, ³Ottawa Hospital Research Institute, Ottawa, ON, Canada, ⁴University of Toronto, Toronto, ON, Canada
*Purpose: Previously we reported a novel biomarker gene set for the identification of tolerance in murine models of rapamycin-induced cardiac tolerance and spontaneous hepatic tolerance.…
2019 American Transplant Congress
Alcohol Recidivism In Liver Transplant Recipients With Alcoholic Liver Disease: Does Six-months Abstinence Rule Still Holds True?
S. K. Satapathy¹, C. Thornburgh¹, J. Yu², J. Eason¹, S. Kedia², D. Maluf¹
¹UTHSC, Memphis, TN, ²University of Memphis, Memphis, TN
*Purpose: Liver transplant for alcoholic liver disease (ALD) continues to be a challenge for transplant centers, particularly related to the ethical dilemma of transplanting or…