Articles tagged "Liver transplantation"

2019 American Transplant Congress
Correlations between Preoperative Hepatic Venous Pressure Gradient and Graft Hemodynamics after Reperfusion in Living Donor Liver Transplantation
H. Matsushima, M. Fujiki, K. Sasaki, F. Aucejo, T. Diago Uso, C. Kwon, B. Eghtesad, C. Miller, C. Quintini, K. Hashimoto
General Surgery, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland Clinic, Cleveland, OH
*Purpose: Hepatic venous pressure gradient (HVPG) is known to correlate with severity of portal hypertension in patients with liver cirrhosis. We retrospectively investigated the clinical…
2019 American Transplant Congress
Patients With Persistently Low MELD-Na Scores Continue To Be At Risk Of Liver Related Death
N. Mazumder, K. Atiemo, S. Montag, A. Daud, A. Kho, M. Abecassis, J. Levitsky, D. Ladner
Northwestern Memorial Hospital, Chicago, IL
*Purpose: The Model for End Stage Liver Disease-Sodium (MELD-Na) score is a reliable predictor of 90-day mortality however its long term predictive ability is unclear,…
2019 American Transplant Congress
Metabolic Liver Transplant: A Single Cooperative 2002-2017
N. Yazigi¹, K. Chapman²
¹Transplantation, MedStar Georgetown University Hospital, Washigton, DC, ²Transplantation, Children's National Rare Disease Institute, Washington, DC
*Purpose: Liver transplant (LT) can increase quality and quantity of life for patients with inherited metabolic diseases (IMDs) who suffer severe and unpredictable complications despite…
2019 American Transplant Congress
Long Term Outcomes of Patients Transplanted for Hepatocellular Carcinoma with Human Immunodeficiency Virus Infection
R. Gedaly-Eidelman, E. Chacon, P. Eman, M. Gupta, J. Berger, A. El-Husseini, X. Mei, F. Marti, L. Turcios, M. Shah
University of Kentucky, Lexington, KY
*Purpose: Several studies have reported that HIV+ patients are 4-6 times more likely to develop HCC than uninfected individuals. Our aim was to assess outcomes…
2019 American Transplant Congress
Early Everolimus Conversion For Renal Protection In Liver Transplantation: The Sooner The Better?
M. Tomeczkowicz, N. Sulejmani, A. Jantz, B. Summers, T. Larson, R. Salgia
Henry Ford Health System, Detroit, MI
*Purpose: Calcineurin inhibitors (CNI) are the mainstay of immunosuppressive therapy in transplantation; however, a major side effect limiting CNI use is nephrotoxicity. Mammalian target of…
2019 American Transplant Congress
Pregnancy Outcomes by Conception Age in Female Liver Transplant Recipients
M. Sarkar¹, L. A. Coscia², D. Kliniewski², S. Rao³, S. Constantinescu⁴, M. J. Moritz⁵
¹Medicine, University of California San Francisco, San Francisco, CA, ²Gift of Life Institute, Transplant Pregnancy Registry International, Philadelphia, PA, ³Medicine, University of Virginia Health System, Charlottesville, VA, ⁴Lewis Katz School of Medicine, Temple University, Philadelphia, PA, ⁵Surgery, Lehigh Valley Health Network, Allentown, PA
*Purpose: The purpose of this study is to compare pregnancy outcomes in liver transplant recipients by different conception ages. Background: Over 30% of female transplant…
2019 American Transplant Congress
Barriers to Pre-Transplant Immunization: A Qualitative Study of Pediatric Liver-Transplant Stakeholders
A. G. Feldman¹, R. Marsh², A. Kempe³, M. Morris²
¹Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado, Aurora, CO, ²University of Colorado, Aurora, CO, ³Pediatrics, University of Colorado, Aurora, CO
*Purpose: Less than 30% of pediatric liver transplant recipients are up-to-date on age-appropriate immunizations at the time of transplant despite being at high-risk for infections…
2019 American Transplant Congress
Discovery and Validation of an Early Post-Transplant Biomarker Model Predictive of Chronic Kidney Disease in Liver Transplant Recipients
J. Levitsky¹, S. Asrani², G. Klintmalm², T. Schiano², A. Moss³, K. Chavin⁴, C. Miller⁵, L. Zhao⁶, K. Guo⁶, N. Bridges⁷, J. Odim⁷, M. Brown⁷, D. Ikle⁸, B. Armstrong⁸, M. Abecassis⁹
¹Gastroenterology and Hepatology, Northwestern University, Chicago, IL, ²Baylor, Dallas, TX, ³Mayo Arizona, Phoenix, AZ, ⁴Case Western, Cleveland, OH, ⁵Cleveland Clinic, Cleveland, OH, ⁶Northwestern University, Chicago, IL, ⁷NIAID, Bethesda, MD, ⁸Rho, Chapel Hill, NC, ⁹Comprehensive Transplant Center, Northwestern University, Chicago, IL
*Purpose: A significant proportion of patients develop chronic kidney disease after liver transplantation (LT). We aimed to develop clinical/protein models to predict future GFR deterioration…
2019 American Transplant Congress
Hepatocyte SIRT1 Modulates ATF4/CHOP and Mitigates Liver Transplant Ischemia-Reperfusion Injury: From Bench-to-Bedside
H. Hirao¹, S. Kageyama¹, K. Kadono¹, K. Nakamura¹, T. Ito¹, K. J. Dery¹, D. Oncel¹, X. Li², B. Ke¹, F. M. Kaldas¹, R. W. Busuttil¹, J. W. Kupiec‐Weglinski¹
¹Surgery, Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA, ²National Institute of Environmental Health Sciences, Research Triangle Park, NC
*Purpose: We and others have reported on benefits of endoplasmic reticulum (ER) stress modulation against hepatic ischemia-reperfusion injury (IRI) in orthotopic liver transplantation (OLT). Although…
2019 American Transplant Congress
The Comparative Safety and Efficacy of Direct Acting Oral Anticoagulants Relative to Warfarin Following Liver Transplantation
A. Santeusanio, A. Weinberg, T. Schiano
Mount Sinai Hospital, New York, NY
*Purpose: This study describes the comparative safety and efficacy of direct acting oral anticoagulants (DOACs) relative to warfarin following liver transplantation, at a large academic…