ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2019 American Transplant Congress

    Cytomegalovirus (CMV) Infection Induces an Angiogenic Response through Hepatic Stellate Cells (HSCs) and Leads to Early Post-Transplant Liver Fibrosis (LF) and Poor Graft Survival

    B. H. Ozdemir1, G. Ozgun1, E. H. Ayvazoglu Soy2, N. Haberal1, G. Moray2, M. Haberal2

    1Pathology, Baskent University, Ankara, Turkey, 2Transplantation, Baskent University, Ankara, Turkey

    *Purpose: The ability of the CMV to infect the endothelial cells (ECs) is critical. CMV can increase EC adhesion, permeability, and create a pro-inflammatory environment…
  • 2019 American Transplant Congress

    Predicting HCC Recurrence Following Liver Transplant – A Machine Learning Approach

    L. F. Lau1, W. Nelson2, A. Gorgen1, L. Erdman2, P. Abreu1, A. Goldenberg2, G. Sapisochin1

    1Department of Surgery, University of Toronto, Toronto, ON, Canada, 2The Center for Computational Medicine, The Hospital for Sick Children, Toronto, ON, Canada

    *Purpose: The liver transplant listing criteria for hepatocellular carcinoma (HCC) is controversial. Policies aim to prevent tumor recurrence but it has been difficult to encompass…
  • 2019 American Transplant Congress

    Occult Liver Graft Fibrosis Prior to Transplantation Influences Clinical Outcomes

    H. Hirao, T. Ito, K. Kadono, S. Kageyama, K. Nakamura, K. J. Dery, B. Ke, F. M. Kaldas, R. W. Busuttil, J. W. Kupiec‐Weglinski

    Surgery, Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA

    *Purpose: Liver transplantation (LT) has become a standard therapy for the management of end-stage liver disease, while early allograft dysfunction (EAD) remains a serious problem.…
  • 2019 American Transplant Congress

    Variation in Racial Disparities in Liver Transplant Outcomes by Hospital Quality

    K. Ross, R. Patzer, R. Lynch

    Emory University, Emory Transplant Center, Atlanta, GA

    *Purpose: Black patients experience inferior outcomes after liver transplant (LTx). Studies of other outcomes have shown that disparities are partially attributable to variation in quality…
  • 2019 American Transplant Congress

    Tubastatin-A, an HDAC6 Inhibitor, is Protective in Liver Ischemia Reperfusion Injury and Acetaminophen-Mediated Liver Injury

    S. Concors1, D. Murken1, P. Hernandez1, D. Aufhauser1, Z. Wang1, G. Ge1, L. Krumeich1, T. Bhatti2, A. Kozikowski3, W. Hancock2, M. H. Levine1

    1Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 2Children's Hospital of Philadelphia, Philadelphia, PA, 3Starwise Therapeutics, Madison, WI

    *Purpose: Ischemia reperfusion injury (IRI) causes morbidity and contributes to early graft loss in liver transplantation and no current therapy exists. Liver injury complicates other…
  • 2019 American Transplant Congress

    Pre-Liver Transplant Renal Dysfunction is an Independent Predictor of Post-Liver Transplant Return to the Operating Room

    H. M. Wadei, M. L. Mai, C. Taner, A. P. Keaveny, S. Mao, P. Abader, P. Kroner, K. Croome

    Department of Transplant, Mayo Clinic, Jacksonville, FL

    *Purpose: Pre-liver transplant (LT) renal dysfunction predicts worse outcomes post-LT but the reasons for this are unclear. We aimed at identifying the effect of pre-LT…
  • 2019 American Transplant Congress

    Dobutamine Stress Echocardiography is a Poor Predictor of Clinically Significant Coronary Artery Disease in Patients Undergoing Liver Transplant Evaluation

    D. L. Hughes1, J. Rice1, J. R. Burton1, E. A. Pomfret2, J. J. Pomposelli2, A. V. Ambardekar3, S. M. Mandell4, M. S. Kriss1

    1Division of Gastroenterology & Hepatology, University of Colorado School of Medicine (UCSOM), Aurora, CO, 2Division of Transplant Surgery, UCSOM, Aurora, CO, 3Division of Cardiology, UCSOM, Aurora, CO, 4Department of Anesthesiology, UCSOM, Aurora, CO

    *Purpose: Given the high incidence of major cardiac events in the first year post-liver transplantation (LT) (>30%), the aim of this study was to determine…
  • 2019 American Transplant Congress

    Predicting Risk of Cytomegalovirus with Viral-Antigen-Specific CD154+ T-cells after Liver or Intestine Transplantation

    C. Ashokkumar, K. Soltys, M. Green, G. Mazariegos, G. Bond, K. Jones, A. Rzempoluch, M. Zaccagnini, P. Sethi, B. W. Higgs, R. Sindhi

    Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    *Purpose: Cytomegalovirus (CMV)-specific T-cells express IFNγ, measure cell-mediated immunity to CMV and can guide the timing and duration of antiviral therapy. CMV-specific T-cells also co-express…
  • 2019 American Transplant Congress

    Allograft Quality Impacts Simultaneous Liver Kidney Transplant Survival Outcomes in Recipients That Undergo Liver Re-Transplantation

    J. Reyes, M. Eerhart, C. Blanton, P. Chlebeck, E. Polyak, Y. Yankol, L. Fernandez

    Department of Surgery, University of Wisconsin - Madison, Madison, WI

    *Purpose: The only effective therapeutic strategy for irreversible liver graft failure is re-transplantation. The impact of liver and kidney quality in secondary SLK (sSLK) survival…
  • 2019 American Transplant Congress

    Clinical Outcomes of Patients with Portal Vein Tumor Thrombi after Living Donor Liver Transplantation

    D. Kim

    Surgery, Seoul St. Mary's Hospital, Catholic University of Korea, Seoul, Korea, Republic of

    *Purpose: Patient selection criteria for living donor liver transplantation(LDLT) with hepatocellular carcinoma are generally wider than those for deceased donor liver transplantation. It is widely…
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