Articles tagged "Liver transplantation"

2019 American Transplant Congress
Combined Ischemic and Rapamycin Preconditioning Alleviated Liver Ischemia and Reperfusion Injury by Restoring Autophagy in Old Mice
Z. Rao, X. Pan, W. Zhong, Z. Ding, H. Zhou, C. Liu
The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Old livers are more damaged by hepatic ischemia and reperfusion (IR) injury than young livers. The aim of this study was to investigate the…
2019 American Transplant Congress
Measuring of Outcomes in Liver Transplant Patients with or without Splenectomy: A Meta Analysis
M. Chen, B. Huang, Y. Zhang, W. Ju, X. He
Transplant Center, Sun Yat-sen University, Guangzhou, China
*Purpose: Splenectomy is performed in liver transplantation (LT) to regulate the portal vein pressure. Researchers have reported beneficial effects of splenectomy on rejection prevention, protection…
2019 American Transplant Congress
Anticoagulation in Post-Liver Transplant Recipients with Portal Vein Thrombosis
L. Schumacher¹, L. Lindberg¹, D. Alonso², R. Gilroy³, J. Krong⁴, L. Dong⁴, S. LeCorchick¹
¹Department of Pharmacy, Intermountain Medical Center, Murray, UT, ²Transplant Surgery, Intermountain Medical Center, Murray, UT, ³Transplant Hepatology, Intermountain Medical Center, Murray, UT, ⁴Department of Transplant, Intermountain Medical Center, Murray, UT
*Purpose: The purpose of this study is to compare safety and efficacy outcomes in liver transplant recipients with portal vein thrombosis (PVT) at the time…
2019 American Transplant Congress
Recipient TIM4 Expression is Essential for Hepatocellular Function in Liver Transplantation
K. Kadono, S. Kageyama, H. Hirao, K. Nakamura, K. J. Dery, D. Oncel, T. Ito, B. Ke, F. M. Kaldas, R. W. Busuttil, J. W. Kupiec‐Weglinski
Dumont-UCLA Transplant Center, UCLA, Los Angeles, CA
*Purpose: Hepatic ischemia-reperfusion injury (IRI) represents a major risk factor of early graft dysfunction and predisposes to rejection in orthotopic liver transplantation (OLT). Previous studies…
2019 American Transplant Congress
Increasing Incidence and Transplantation of Individuals Listed with Alcoholic Liver Disease
E. L. Godfrey¹, A. Rana², J. A. Goss²
¹Department of Student Affairs, Baylor College of Medicine, Houston, TX, ²Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: Alcoholic liver disease (ALD) has recently become the most common indication for liver transplantation in the US; it is important to characterize changes in…
2019 American Transplant Congress
Tracheostomy Following Liver Transplantation
J. Almario, O. Okoye, M. Spaggiari, K. Jacob, P. Di Cocco, E. Benedetti, I. Tzvetanov
Surgery, University of Illinois at Chicago, Chicago, IL
*Purpose: With the current demand for liver transplantation, sicker patients are frequently transplanted. These patient are at a higher risk of significant morbidity following surgery,…
2019 American Transplant Congress
Tumor Necrosis as a Result to Pre-Transplant Bridging Treatment for Hepatocellular Carcinoma and Its Effect on Post-Transplant Outcome
S. Radunz¹, A. Kirschner¹, J. M. Theysohn², C. Schotten³, T. Benkö¹
¹General, Visceral and Transplant Surgery, University Hospital Essen, Essen, Germany, ²Diagnostic and Interventional Radiology and Neurradiology, University Hospital Essen, Essen, Germany, ³Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany
*Purpose: As a bridge to liver transplantation, locoregional treatments are commonly employed in hepatocellular carcinoma (HCC) patients to prevent tumor progression during waiting time. Objective…
2019 American Transplant Congress
CURATE.AI: Personalized Liver Transplant Tacrolimus Dosing
A. Zarrinpar¹, T. Kee², P. Wang³, J. Khong³, U. Kim¹, J. Chong², J. B. Jeong³, A. T. Truong², S. Tan², B. K. Betzler², W. Ng², C. Ho³, D. Ho²
¹Surgery, University of Florida, Gainesville, FL, ²National University of Singapore, Singapore, Singapore, ³UCLA, Los Angeles, CA
*Purpose: Transplant immunosuppressive regimens include multiple drugs with varying pharmacokinetics, metabolic pathways, and drug-drug interactions. This study aimed to use CURATE.AI, an artificial intelligence platform,…
2019 American Transplant Congress
Inflammation and Fibrosis Are Observed in 34% of Clinically Stable Adult Liver Transplant Recipients
L. Sun¹, J. Levitsky², S. Feng³, A. Humar⁴, A. J. Demetris⁴, J. Emond⁵, A. Shaked⁶, G. Klintmalm⁷, K. Mason⁸, M. DesMarais¹, A. Priore⁹, N. Bridges⁹, B. E. Burrell¹⁰, S. Chandran³, J. Markmann¹¹
¹ITN, San Francisco, CA, ²Northwestern, Chicago, IL, ³UCSF, San Francisco, CA, ⁴UPMC, Pittsburg, PA, ⁵Columbia, New York, NY, ⁶UPenn, Philadelphia, PA, ⁷Baylor, Dallas, TX, ⁸Rho, Chapel Hill, NC, ⁹NIAID, Bethesda, MD, ¹⁰ITN, Bethesda, MD, ¹¹MGH, Boston, MA
*Purpose: OPTIMAL is a 7-center immunosuppression withdrawal (ISW) study in non-autoimmune, non-HCV adult liver transplant recipients ≥3 yrs post-transplant (tx) (NCT02533180). Subjects underwent a screening…
2019 American Transplant Congress
Early Tacrolimus Trough Concentration Variability Could Predict Rejection in Pediatric Liver Transplantation: A Single-Center and Retrospective Research
G. Gu, Q. Xia
Renji Hospital, Shanghai, China
*Purpose: With great development in immunosuppressive therapy, the long-term outcomes and survival time in patients who received solid organ transplantation have been improved remarkably. The…