ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2020 American Transplant Congress

    MTOR Inhibitor Management and Wound Complications in Liver Transplant Recipients Undergoing Subsequent Surgeries

    K. Neuhaus, B. Eghtesad, K. Hashimoto, M. Spinner, J. Bollinger, J. Eckardt

    Cleveland Clinic, Cleveland, OH

    *Purpose: Class-related, concentration-dependent adverse effects associated with mTOR inhibitors (mTORi) include wound complications such as impaired wound healing, incisional hernias, hepatic artery thrombosis, and lymphocele…
  • 2020 American Transplant Congress

    Long Term Ursodeoxycholic Acid Use Does Not Alter Long Term Rejection, Biliary Complication, Mortality or Hospitalization Rates after Liver Transplantation

    T. Ashraf1, V. Mendiratta2, S. Gill1, A. Abdelwahab3, D. Moonka2, S. Jafri2

    1Internal Medicine, Henry Ford Hospital, Detroit, MI, 2Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, 3Wayne State University, Detroit, MI

    *Purpose: Endogenous bile acids are suspected to contribute to hepatobiliary injury after liver transplantation through direct cytotoxic effects. Ursodeoxycholic acid (UDCA) has been shown to…
  • 2020 American Transplant Congress

    A Three-Decade Analysis of Pancreatic Adenocarcinoma Following Liver Transplantation

    O. Y. Mousa1, J. E. Corral2, K. Wijarnpreecha2, R. Shah3, V. S. Louwagie4, M. J. Bartel5, B. Brahmbhatt2

    1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Jacksonville, FL, 3Emory University, Atlanta, GA, 4Mayo Clinic Health System, Mankato, MN, 5Fox Chase Cancer Center, Philadelphia, PA

    *Purpose: Liver transplant (LT) recipients are at risk of serious long term complications, including a higher risk of de novo malignancies compared to the general…
  • 2020 American Transplant Congress

    Normothermic Machine Perfusion of Genetically Modified Pig Livers with Human Blood

    D. Detelich1, T. M. Coe2, C. G. Rickert2, C. Carroll2, N. Serifis2, R. Matheson2, I. Rosales2, W. Qin3, Y. Kan3, J. Layer3, M. Youd3, W. Westlin3, S. Kimura2, A. Azimzadeh2, L. Yang3, J. F. Markmann2

    1Tufts Medical Center, Boston, MA, 2Massachusetts General Hospital, Boston, MA, 3eGenesis, Cambridge, MA

    *Purpose: Barriers to pig-to-human liver xenotransplantation remain, including profound thrombocytopenia, coagulopathy, and rejection. We utilized ex-vivo liver xenoperfusion with human blood to study the human…
  • 2020 American Transplant Congress

    Hepaticojejunostomy versus Duct to Duct Anastomosis in Liver Transplantation: An Old Question Revisited

    A. M. Elsabbagh, M. T. Shamaa, A. Al-Kurd, F. Tinney, T. Ivanics, A. Mohamed, K. Delvecchio, S. Yeddula, M. Rizzari, K. Collins, A. Yoshida, M. Abouljoud, S. Nagai

    Henry Ford Hospital, Detroit, MI

    *Purpose: Two surgical techniques are currently used for biliary reconstruction and each has its advantages/disadvantages. However, it is unclear if the used technique can impact…
  • 2020 American Transplant Congress

    Risk Factors Associated with Hepatic Artery Thrombosis in the Modern Era

    M. Krach, A. Kernodle, P. Chiang, D. Segev, A. Massie, J. Garonzik-Wang

    Johns Hopkins, Baltimore, MD

    *Purpose: Historically, hepatic artery thrombosis (HAT) has been associated with certain risk factors, such as donor age, cold ischemia time, and split grafts; it is unclear…
  • 2020 American Transplant Congress

    Because That is Not How The Hierarchy Works: Primary Care Provider Perspectives on Liver Transplant Referral and Access to Transplant

    V. Madabhushi1, A. Murphy2, C. Reams3, R. Gedaly3, M. Shah3, N. Pope4, M. Gupta5

    1General Surgery, University of Kentucky, Lexington, KY, 2University of Kentucky, College of Medicine, Lexington, KY, 3Surgery, DIvision of Transplant Surgery, University of Kentucky, Lexington, KY, 4University of Kentucky, College of Social Work, Lexington, KY, 5Surgery, Division of Transplant Surgery, University of Kentucky, Lexington, KY

    *Purpose: In rural America, the road to obtaining a liver transplant (LTX) often starts at the primary care provider’s (PCP) office. Patients in rural communities…
  • 2020 American Transplant Congress

    Single Cell RNA Sequencing Analysis of 3 Human Living-Donor Liver Transplant Allograft Biopsies after Infusion of Donor-Derived Regulatory Dendritic Cells

    L. M. Tran1, T. Tabib2, A. F. Zahorchak1, R. Lafyatis2, M. A. Styn1, A. Humar1, F. G. Lakkis1, D. M. Metes1, A. W. Thomson1

    1Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, 2Department of Medicine and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA

    *Purpose: Single-cell RNA sequencing is an emerging, powerful genomic technology that can describe heterogenous cellular populations of whole solid organs with high resolution. We report…
  • 2020 American Transplant Congress

    Temporal Trends in the Incidence and Impact of Biliary Complications Following Liver Transplantation

    K. R. Jackson1, K. Lentine2, M. Schnitzler2, Z. Zhang2, H. Xiao2, J. Motter1, D. Axelrod3, D. Segev1

    1Johns Hopkins University, Baltimore, MD, 2Saint Louis University, Saint Louis, MO, 3University of Iowa, Iowa City, IA

    *Purpose: Biliary complications (BC) are a major threat to successful liver transplantation (LT), as they are associated with a subsequent higher risk of mortality and…
  • 2020 American Transplant Congress

    Pediatric Liver Post-Transplant Length of Stay Index

    T. Zhang1, S. Barrett1, R. Cotton2, T. Galvan2, J. Vierling2, C. O'Mahony2, J. Goss2, A. Rana2

    1Medical Student, Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine, Houston, TX

    *Purpose: PELD scores are used to reduce waitlist mortality, but they do not accurately predict likelihood of prolonged length of stay or higher costs associated…
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