Articles tagged "Liver transplantation"

2020 American Transplant Congress
Taking Liver Transplant to “The Friendly Skies”: A Novel Pilot Program Using Commercial Flights and Ride-Sharing Apps to Minimize Dry-Run Expenses and Expand Potential Donors
G. J. McKenna, N. Onaca, H. Fernandez, E. Martinez, A. Gupta, A. Wall, J. Bayer, R. Ruiz, G. Testa
Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
*Purpose: Growth in liver transplantation means using marginal/DCD donors, however these often fail to yield a suitable organ. Organ procurement can require travelling significant distances,…
2020 American Transplant Congress
Multimodal Strategy for Hepatocellular Carcinoma in the Elderly: To Transplant or Not to Transplant
M. Najjar¹, O. Perez¹, J. Zou¹, S. Sun¹, K. Bruestle¹, P. Jiang¹, E. Verna¹, E. Zheng¹, Y. Saenger¹, A. Mathur¹, A. Griesemer¹, B. Samstein², T. Kato¹, K. Halazun², J. Emond¹
¹Columbia University Irving Medical Center, New York, NY, ²Weill Cornell Medicine, New York, NY
*Purpose: Liver transplantation LT for HCC is curative but entails increased risk and is limited by organ scarcity. Alternative approaches such as locoregional therapy (LRT)…
2020 American Transplant Congress
Low Level CMV Detection and Effectiveness of Low Dose Valganciclovir Prophylaxis in Intermediate-Risk Liver Transplant Recipients
A. Nolan¹, B. Lovett², B. Lindner¹, J. G. Timpone³
¹Department of Pharmacy, Medstar Georgetown University Hospital, Washington, DC, ²Georgetown University School of Medicine, Washington, DC, ³Medstar Georgetown University Hospital, Washington, DC
*Purpose: The purpose of this study is to assess the efficacy of low dose (450 mg/day) valganciclovir in preventing CMV infection in intermediate-risk liver transplant…
2020 American Transplant Congress
T-cell Receptor Deep Sequencing to Distinguish Autoimmune Recurrence from Allograft Rejection in Liver Transplant Patients with Autoimmune Liver Disease
K. J. Yang¹, M. Martinez², B. Shonts¹, C. A. Parks¹, A. Z. Obradovic¹, T. M. Savage¹, E. Spyrou¹, S. Lau¹, M. I. Colquhoun¹, K. Rodgers¹, E. Verna³, S. M. Coley⁴, S. Yang¹, Y. Shen⁵, M. Sykes¹
¹Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY, ²Department of Pediatrics, Columbia University, New York, NY, ³Department of Medicine, Columbia University, New York, NY, ⁴Department of Pathology, Columbia University, New York, NY, ⁵Center for Computational Biology & Bioinformatics, Department of Systems Biology, Columbia University, New York, NY
*Purpose: Patients who undergo liver transplantation for autoimmune liver disease (ALD) experience high rates of graft failure. The relative roles of recurrent ALD and rejection…
2020 American Transplant Congress
Liver Transplantation for Primary Liver Sarcoma in Children-The US Experience from the Scientific Registry for Transplant Recipients (1988-2018)
A. Amin, K. Soltys, S. Ranganathan, G. Bond, A. Khanna, A. Ganoza, Q. Sun, G. Mazariegos, R. Sindhi
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Primary liver sarcomas (PLS) are rare tumors and encompass subtypes with diverse histology and varying outcomes. These subtypes include embryonal sarcoma (ES), rhabdomyosarcoma (RMS),…
2020 American Transplant Congress
National Experience with Living Donor Liver Transplant for Hepatocellular Carcinoma
J. Silverstein¹, F. Yao¹, J. D. Grab², H. Braun², J. Roberts², J. Dodge², N. Mehta¹
¹Dept of Medicine, UCSF, San Francisco, CA, ²Dept of Surgery, UCSF, San Francisco, CA
*Purpose: LDLT is an attractive option to decrease both wait time and risk of waitlist dropout in HCC. This study aimed to evaluate temporal and…
2020 American Transplant Congress
Transmission of Synovial Sarcoma by a Single Multiorgan Donor to Three Solid Organ Transplant Recipients
J. Zhang, J. Lin, Y. Tian
Beijing Friendship Hospital, Capital Medical University, Beijing, China
*Purpose: To report 3 cases of donor-derived synovial sarcoma (SS) by a single multiorgan donor in China.*Methods: SS was diagnosed by the presence of SS18…
2020 American Transplant Congress
Effects of Tenofovir and Entecavir on Glomerular Kidney Function in Liver Transplant Patients: A Nationwide Cohort Study
J. Lee¹, E. Kim¹, S. Yang¹, S. Kim¹, J. Lee¹, J. Park², H. Choi³, B. Kim², D. Joo¹, S. Kim¹, M. Kim¹
¹Department of Transplantation Surgery, Severance Hospital, Seoul, Korea, Republic of, ²Department of Internal Medicine, Severance Hospital, Seoul, Korea, Republic of, ³Department of Internal Medicine, Gangnam Severance Hospital, Seoul, Korea, Republic of
*Purpose: Entecavir and tenofovir are currently the first-line drugs in liver transplantation (LT) patients for the prevention of hepatitis B virus recurrence. Despite its proven…
2020 American Transplant Congress
Bariatric Surgery to Improve Candidacy for Liver Transplantation: A Systematic Review and Meta-Analysis
J. Purvis¹, R. Stahl¹, J. Grams¹, M. Gray¹, D. Eckhoff¹, R. Cannon¹, C. Lewis¹, N. Terrault², J. Locke¹, B. Orandi¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Southern California, Los Angeles, CA
*Purpose: As non-alcoholic steatohepatitis grows as an indication for liver transplant, the challenge managing obese pre-liver transplant patients will become more pronounced, especially because most…
2020 American Transplant Congress
Brincidofovir for Treatment of Disseminated Human Adenovirus Infection in Pediatric Solid Organ Transplant Recipients
J. Londeree¹, R. Garro¹, R. Romero², R. George¹, P. Winterberg¹, R. Liverman³, A. Serluco³, S. Shin¹, I. Yildirim⁴
¹Pediatric Nephrology, Emory, Atlanta, GA, ²Pediatric Hepatology and Gastroenterology, Emory, Atlanta, GA, ³Pharmacy, Children's Healthcare of Atlanta, Atlanta, GA, ⁴Pediatric Infectious Disease, Emory, Atlanta, GA
*Purpose: Brincidofovir (BCV) is an investigational antiviral drug with potency against Human Adenovirus (HAdV). We describe four cases of disseminated HAdV infection treated with (BCV)…