Articles tagged "Liver transplantation"

2020 American Transplant Congress
Hepatologist and Surgeon Experiences Counseling Liver Transplant Candidates for an Organ Offer Decision
C. Schaffhausen¹, M. Bruin², S. Chu³, S. Chinnakotla⁴, J. R. Lake⁵, A. K. Israni⁶
¹Hennepin Heathcare Research Institute (HHRI), Minneapolis, MN, ²College of Design, University of Minnesota (UMN), Minneapolis, MN, ³College of Design, UMN, Minneapolis, MN, ⁴Department of Surgery, UMN, Minneapolis, MN, ⁵Division of Gastroenterology, Hepatology, and Nutrition, UMN, Minneapolis, MN, ⁶Department of Medicine, Hennepin Healthcare, UMN, Minneapolis, MN
*Purpose: Liver transplant candidates receive counseling during evaluations to understand donor risk factors. After long periods on the waitlist, candidates who receive an offer for…
2020 American Transplant Congress
Social Support in the Peri-Liver Transplant Period Affects Post-Transplant Survival, Rejection Rate and Length of Stay
T. Ashraf¹, V. Mendiratta², S. Gill¹, A. Abdelwahab³, D. Moonka², S. Jafri²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI, ²Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, ³Wayne State University, Detroit, MI
*Purpose: Although social support is a key component of the pre-transplant evaluation, it’s effect on post-transplant outcomes remains understudied. The purpose of this study was…
2020 American Transplant Congress
Liver Transplant Outcomes in Menopausal Women During the Meld Era
C. Brady¹, A. Parish², D. Niedzwiecki²
¹Division of Gastroenterology, Duke University Med Ctr., Durham, NC, ²Department of Biostatistics and Bioinformatics, Duke University Med Ctr., Durham, NC
*Purpose: From an epidemiology perspective, menopausal women are an increasing proportion of the population, and menopause represents an important stage in which hormonal changes and…
2020 American Transplant Congress
Molecular Phenotypes of Liver Transplant Injury: The INTERLIVER Study
K. S. Madill-Thomsen¹, P. F. Halloran¹, &. the INTERLIVER Study Group²
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²., ., AB, Canada
*Purpose: Liver parenchymal injury phenotypes are difficult to evaluate by histology but could be amenable to molecular assessment. Having developed a Molecular Microscope® Diagnostic System…
2020 American Transplant Congress
Factors Associated with Hepatocellular Carcinoma Understaging for Liver Transplantation, and Variation in Understaging by Transplant Center
N. Mahmud¹, M. Hoteit¹, D. Goldberg²
¹Hospital of the University of Pennsylvania, Philadelphia, PA, ²University of Miami, Miami, FL
*Purpose: Hepatocellular carcinoma (HCC) may be cured by liver transplantation (LT) in selected patients, though recurrence rates remain high. Patients who are reported as within…
2020 American Transplant Congress
Predictors of Estimated GFR and Recurrent Chronic Kidney Disease (CKD) after Simultaneous Liver and Kidney Transplantation (SLKT): Results from the US Multicenter SKLT Consortium
P. Sharma¹, Z. Sui¹, M. Zhang¹, J. Magee¹, P. Barman², Y. Patel³, K. Walters⁴, S. Biggins⁵, A. Schluger⁶, G. Cullaro⁷, R. Wong⁸, J. Lai⁸, J. Jo⁹, J. Sinha⁹, L. VanWagner⁹, E. Verna⁷
¹Michigan Medicine, Ann Arbor, MI, ²UCSD, San Diego, CA, ³Duke, Durham, NC, ⁴UCLA, LA, CA, ⁵University of Washington, Seattle, WA, ⁶Westchester Medical Center, Weschester, NY, ⁷Columbia, New York, NY, ⁸UCSF, San Francisco, CA, ⁹Northwestern, Chicago, IL
*Purpose: SLKT is a life-saving intervention for patients with decompensated cirrhosis and concomitant end stage renal disease, irreversible acute kidney injury and select inherited metabolic…
2020 American Transplant Congress
A Data-Driven Approach to Defining the Volume-Outcome Relationship in Liver Transplantation
M. D. Bailey, E. L. Godfrey, W. C. Frankel, A. Rana
Baylor College of Medicine, Houston, TX
*Purpose: Patients with end-stage liver disease (ESLD) who undergo liver transplantation experience significant survival benefit, with a 1-year survival rate after liver transplantation of 91%.…
2020 American Transplant Congress
Black Patients with Cirrhosis Have Worse Liver-Related Outcomes: A Large Multicenter Study
N. R. Mazumder¹, K. Atiemo², K. Jackson³, A. Daud⁴, A. Kho³, L. G. Gabra⁵, J. Levitsky¹, D. P. Ladner⁴
¹Gastroenterology and Hepatology, Northwestern University, Chicago, IL, ²Department of Surgery, Tulane Abdominal Transplant Institute, New Orleans, LA, ³Center for Health Information Partnerships, Northwestern University, Chicago, IL, ⁴Transplant Surgery, Northwestern University, Chicago, IL, ⁵Feinberg School of Medicine, Northwestern University, Chicago, IL
*Purpose: Racial disparity is influential in liver cirrhosis. Estimates of its magnitude have been limited by lack of large, longitudinal data that track patients from…
2020 American Transplant Congress
Single-Cell RNA Sequencing Reveals Gene Expression Profiling of Ischemia Reperfusion Injury
L. Wang, S. He, J. Xu, Z. Guo, X. He
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
*Purpose: Ischemia-reperfusion injury (IRI) during liver transplantation is an important factor that leads to graft dysfunction and even recipient death. This study aims to explore…
2020 American Transplant Congress
Concurrent Final Acceptance Associated with Decreased Deceased Donor Liver Utilization
A. Robinson¹, K. Shutterly², M. Sellers³, J. Rosendale¹, D. Brockmeier⁴
¹United Network for Organ Sharing, Richmond, VA, ²Center for Organ Recovery and Education, Pittsburgh, PA, ³Emory University Hospital and LifeLink of Georgia, Atlanta, GA, ⁴Mid-America Transplant Services, St. Louis, MO
*Purpose: With broader sharing for candidates with high MELD scores, it is not unusual for liver candidates to receive offers from multiple donors. Accepting multiple…